Q8GWJ4
Gene name |
OSB3 (At5g44785, K23L20.13, T19K24.10) |
Protein name |
Protein OSB3, chloroplastic/mitochondrial |
Names |
Organellar single-stranded DNA-binding protein 3 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT5G44785 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8GWJ4
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8GWJ4-F1 | Predicted | AlphaFoldDB |
51 variants for Q8GWJ4
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_5_18073006_T_C | 2 | N>S | No | 1000Genomes | |
| tmp_5_18072991_G_T | 7 | T>K | No | 1000Genomes | |
| ENSVATH07336003 | 9 | T>I | No | 1000Genomes | |
| ENSVATH07336003 | 9 | T>K | No | 1000Genomes | |
| ENSVATH07336001 | 12 | V>A | No | 1000Genomes | |
| ENSVATH07336002 | 12 | V>L | No | 1000Genomes | |
| ENSVATH00707354 | 17 | Y>N | No | 1000Genomes | |
| ENSVATH12524009 | 27 | Q>K | No | 1000Genomes | |
| ENSVATH03353885 | 45 | G>S | No | 1000Genomes | |
| ENSVATH12524008 | 46 | G>R | No | 1000Genomes | |
| ENSVATH07335998 | 54 | V>E | No | 1000Genomes | |
| ENSVATH07335996 | 61 | N>Y | No | 1000Genomes | |
| ENSVATH00707352 | 63 | A>V | No | 1000Genomes | |
| ENSVATH07335995 | 73 | K>T | No | 1000Genomes | |
| ENSVATH12524006 | 75 | E>D | No | 1000Genomes | |
| tmp_5_18072782_T_C | 77 | K>E | No | 1000Genomes | |
| tmp_5_18072702_T_A | 103 | K>N | No | 1000Genomes | |
| ENSVATH12523984 | 115 | G>D | No | 1000Genomes | |
| ENSVATH07335991 | 118 | S>T | No | 1000Genomes | |
| ENSVATH07335988 | 130 | D>E | No | 1000Genomes | |
| ENSVATH12523981 | 131 | L>S | No | 1000Genomes | |
| tmp_5_18072499_C_T | 144 | R>Q | No | 1000Genomes | |
| tmp_5_18072460_G_A | 157 | P>L | No | 1000Genomes | |
| ENSVATH03353883 | 160 | V>L | No | 1000Genomes | |
| ENSVATH07335980 | 182 | S>Y | No | 1000Genomes | |
| ENSVATH12523873 | 183 | T>R | No | 1000Genomes | |
| ENSVATH12523872 | 200 | K>N | No | 1000Genomes | |
| tmp_5_18071970_G_T | 225 | P>H | No | 1000Genomes | |
| ENSVATH12523867 | 231 | H>Y | No | 1000Genomes | |
| ENSVATH12523831 | 261 | A>V | No | 1000Genomes | |
| tmp_5_18071778_C_T | 263 | D>N | No | 1000Genomes | |
| ENSVATH00707343 | 270 | E>K | No | 1000Genomes | |
| ENSVATH00707343 | 270 | E>Q | No | 1000Genomes | |
| ENSVATH00707342 | 271 | E>A | No | 1000Genomes | |
| ENSVATH07335967 | 274 | F>L | No | 1000Genomes | |
| tmp_5_18071565_A_G | 305 | L>S | No | 1000Genomes | |
| ENSVATH12523828 | 314 | V>M | No | 1000Genomes | |
| tmp_5_18071386_C_G | 330 | M>I | No | 1000Genomes | |
| ENSVATH07335959 | 349 | E>D | No | 1000Genomes | |
| ENSVATH12523827 | 350 | R>K | No | 1000Genomes | |
| ENSVATH00707338 | 352 | F>L | No | 1000Genomes | |
| ENSVATH00707337 | 361 | E>K | No | 1000Genomes | |
| ENSVATH12523803 | 364 | V>I | No | 1000Genomes | |
| tmp_5_18071276_G_C | 367 | P>R | No | 1000Genomes | |
| ENSVATH03353870 | 375 | K>E | No | 1000Genomes | |
| ENSVATH00707334 | 378 | E>K | No | 1000Genomes | |
| tmp_5_18071145_T_G | 382 | N>T | No | 1000Genomes | |
| tmp_5_18071137_C_T | 385 | E>K | No | 1000Genomes | |
| ENSVATH03353867 | 396 | D>H | No | 1000Genomes | |
| ENSVATH12523769 | 398 | R>K | No | 1000Genomes | |
| tmp_5_18070896_T_A | 435 | E>V | No | 1000Genomes |
No associated diseases with Q8GWJ4
No regional properties for Q8GWJ4
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q8GWJ4 | |||
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| chloroplast | A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. |
| mitochondrial nucleoid | The region of a mitochondrion to which the DNA is confined. |
| nucleoid | The region of a virus, bacterial cell, mitochondrion or chloroplast to which the nucleic acid is confined. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| single-stranded DNA binding | Binding to single-stranded DNA. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| mitochondrial DNA replication | The process in which new strands of DNA are synthesized in the mitochondrion. |
| positive regulation of helicase activity | Any process that activates or increases the activity of a helicase. |
3 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9SX99 | OSB1 | Protein OSB1, mitochondrial | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9FYJ2 | OSB4 | Protein OSB4, chloroplastic | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8GXH3 | OSB2 | Protein OSB2, chloroplastic | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MNLISRTLTR | AVSSSLYHSK | AAKLPTQKWI | ISQQIRVFSA | TVISGGGKKP | LAKVSVKPPL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| NVATEKESTP | PKKIEYKPEI | SNWINLIGFV | EQPVQFGPCS | DGKFWAGTVI | SQRSGSKSSN |
| 130 | 140 | 150 | 160 | 170 | 180 |
| FWIPIIFEGD | LAKIAVQHVK | KEDRIHVSGK | LFIDSPPPNV | TYSQSNVQVM | VQNLNFVQAA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| TSTTKTISPP | EKEVTSIKKK | PARSKKVKVI | DEETSNSWKH | LIENPKEWLD | HRGNKANGLV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| KPGHPDFKMK | VGGLSLWLST | APDWALLKLE | ELKFDVLVPK | GNIKLNQLKG | EESWKDLVQN |
| 310 | 320 | 330 | 340 | 350 | 360 |
| PDKWLDNRSD | KTNVKYPDFK | HKETGEALWM | TNSPIWVLSK | LPPLKKNQER | PFMSNKVSQL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| ELDVEVPKGN | LKQLKREEIW | KNLVENPSKW | WDNRLDKRNP | KGPDFKHKET | GEALWIGDSP |
| 430 | |||||
| TWALSKLPPL | KKNQERPVMA |