AiPD: Autoinhibited Protein Database

Gene name	Strip2 (Fam40b, Kiaa1170, Stripb)
Protein name	Striatin-interacting proteins 2
Names	Protein FAM40B
Species	Mus musculus (Mouse)
KEGG Pathway	mmu:320609
EC number
Protein Class

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

298-399 (Predicted disordered autoinhibitory region) PR

298-399 (Predicted disordered autoinhibitory region)

cis-regPred

No accessory elements

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q8C9H6-F1	Predicted				AlphaFoldDB

Variant ID(s)	Position	Change	Diseaes Association	Provenance
rs3388804030	59	T>S	No	EVA
rs3388814961	72	A>T	No	EVA
rs3388819749	84	L>Q	No	EVA
rs3388806260	120	M>T	No	EVA
rs3388814914	136	K>R	No	EVA
rs3388818876	158	V>M	No	EVA
rs3388803987	184	M>L	No	EVA
rs3388814969	224	R>S	No	EVA
rs3396590175	225	L>Q	No	EVA
rs3388819079	257	L>F	No	EVA
rs3396654023	269	G>C	No	EVA
rs3396432055	269	G>D	No	EVA
rs3388822563	272	P>H	No	EVA
rs3388822563	272	P>L	No	EVA
rs3396580240	274	F>L	No	EVA
rs3396580673	278	K>N	No	EVA
rs3388819084	307	E>D	No	EVA
rs3388820232	312	P>L	No	EVA
rs3388813219	398	E>D	No	EVA
rs3388799230	410	P>T	No	EVA
rs3396645777	428	L>M	No	EVA
rs3396764507	428	L>R	No	EVA
rs3388820965	431	A>T	No	EVA
rs3388818915	463	V>I	No	EVA
rs3388814958	491	N>I	No	EVA
rs3388814919	511	P>Q	No	EVA
rs3388822567	525	Q>E	No	EVA
rs3388820925	525	Q>H	No	EVA
rs3388826634	552	A>T	No	EVA
rs3388813634	564	L>I	No	EVA
rs3388809862	648	Q>*	No	EVA
rs3388813671	665	Q>K	No	EVA
rs3388820269	691	R>M	No	EVA
rs3388820975	719	V>A	No	EVA
rs3396591555	724	K>VLGLYL*	No	EVA
rs3388826603	732	R>H	No	EVA
rs3388799175	757	W>L	No	EVA
rs3395844397	763	I>M	No	EVA
rs3396653978	764	D>E	No	EVA
rs3396515558	767	P>T	No	EVA
rs3388820218	842	Q>H	No	EVA

Type	Name	Position	InterPro Accession
domain	FCH domain	1 - 93	IPR001060
domain	SH3 domain	538 - 599	IPR001452
domain	HR1 rho-binding domain	397 - 474	IPR011072
domain	F-BAR domain	1 - 263	IPR031160
domain	FNBP1L, SH3 domain	541 - 597	IPR035493
domain	FNBP1L, F-BAR domain	5 - 256	IPR035494

		Description
EC Number
Subcellular Localization	Cytoplasm	Enriched in lamellipodia
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

Name	Definition
cytoplasm	The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
cytosol	The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

Name	Definition
No GO annotations for molecular function

Name	Definition
cell migration	The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms.
cytoskeleton organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures.
regulation of cell shape	Any process that modulates the surface configuration of a cell.

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
P53917	FAR11	Factor arrest protein 11	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	PR
Q0P5J8	STRIP1	Striatin-interacting protein 1	Bos taurus (Bovine)	PR
Q5VSL9	STRIP1	Striatin-interacting protein 1	Homo sapiens (Human)	PR
Q9ULQ0	STRIP2	Striatin-interacting protein 2	Homo sapiens (Human)	PR
Q8C079	Strip1	Striatin-interacting protein 1	Mus musculus (Mouse)	PR
Q803T2	strip1	Striatin-interacting protein 1 homolog	Danio rerio (Zebrafish) (Brachydanio rerio)	PR