AiPD: Autoinhibited Protein Database

Gene name	Strip1 (Fam40a, Kiaa1761)
Protein name	Striatin-interacting protein 1
Names	Protein FAM40A
Species	Mus musculus (Mouse)
KEGG Pathway	mmu:229707
EC number
Protein Class

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

1-97 (Predicted disordered autoinhibitory region) PR

1-97 (Predicted disordered autoinhibitory region)

cis-regPred

No accessory elements

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q8C079-F1	Predicted				AlphaFoldDB

Variant ID(s)	Position	Change	Diseaes Association	Provenance
rs3388655390	22	P>S	No	EVA
rs3388657058	90	E>G	No	EVA
rs3388637667	112	K>T	No	EVA
rs3388651959	191	M>V	No	EVA
rs3388645772	201	S>N	No	EVA
rs3388645743	227	V>E	No	EVA
rs3388654876	306	S>I	No	EVA
rs3393041296	394	E>G	No	EVA
rs3393425219	397	P>H	No	EVA
rs3388649992	398	L>P	No	EVA
rs3393505806	403	V>G	No	EVA
rs3393251297	404	M>K	No	EVA
rs3393505903	418	C>*	No	EVA
rs3388655402	448	T>S	No	EVA
rs3388657938	479	A>VSDG*	No	EVA
rs3388652023	483	A>G	No	EVA
rs3388645759	488	E>D	No	EVA
rs3388651965	496	G>A	No	EVA
rs3388645729	507	E>D	No	EVA
rs3388655344	521	M>V	No	EVA
rs3388657917	528	L>I	No	EVA
rs3388657865	565	V>L	No	EVA
rs3388637665	592	N>S	No	EVA
rs3388656984	599	Y>C	No	EVA
rs3388659293	624	Y>F	No	EVA
rs3388660151	636	Y>C	No	EVA
rs3388660200	661	C>R	No	EVA
rs3388653874	699	K>N	No	EVA
rs3388652996	699	K>T	No	EVA
rs3388652331	713	V>M	No	EVA
rs3388661020	766	A>T	No	EVA

Type	Name	Position	InterPro Accession
domain	Oxoglutarate/iron-dependent dioxygenase	191 - 295	IPR005123
domain	Non-haem dioxygenase N-terminal domain	41 - 149	IPR026992
domain	Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain	196 - 294	IPR044861

		Description
EC Number
Subcellular Localization	Cytoplasm	Enriched on the plasma membrane
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

Name	Definition
cytosol	The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
nucleus	A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

Name	Definition
protein kinase binding	Binding to a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
small GTPase binding	Binding to a small monomeric GTPase.

Name	Definition
cortical actin cytoskeleton organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of actin-based cytoskeletal structures in the cell cortex, i.e. just beneath the plasma membrane.
cytoskeleton organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures.
regulation of cell morphogenesis	Any process that modulates the frequency, rate or extent of cell morphogenesis. Cell morphogenesis is the developmental process in which the shape of a cell is generated and organized.

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
P53917	FAR11	Factor arrest protein 11	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	PR
Q0P5J8	STRIP1	Striatin-interacting protein 1	Bos taurus (Bovine)	PR
Q9ULQ0	STRIP2	Striatin-interacting protein 2	Homo sapiens (Human)	PR
Q5VSL9	STRIP1	Striatin-interacting protein 1	Homo sapiens (Human)	PR
Q8C9H6	Strip2	Striatin-interacting proteins 2	Mus musculus (Mouse)	PR
Q803T2	strip1	Striatin-interacting protein 1 homolog	Danio rerio (Zebrafish) (Brachydanio rerio)	PR