Q84JI6

PR
Gene name
B''EPSILON (At1g03960, F21M11.11)
Protein name
Probable serine/threonine protein phosphatase 2A regulatory subunit B''epsilon
Names
AtB''epsilon
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT1G03960
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

31-145 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q84JI6

Entry ID Method Resolution Chain Position Source
AF-Q84JI6-F1 Predicted AlphaFoldDB

50 variants for Q84JI6

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_1_1014110_A_G 9 D>G No 1000Genomes
tmp_1_1014140_A_T 19 Q>L No 1000Genomes
tmp_1_1014193_G_C 37 D>H No 1000Genomes
tmp_1_1014199_T_C 39 F>L No 1000Genomes
tmp_1_1014202_T_C 40 S>P No 1000Genomes
tmp_1_1014217_C_T 45 L>F No 1000Genomes
ENSVATH01010508 47 E>Q No 1000Genomes
ENSVATH01010512 67 K>I No 1000Genomes
ENSVATH01010511 67 K>Q No 1000Genomes
tmp_1_1014394_C_T 72 P>S No 1000Genomes
ENSVATH01010513 74 V>L No 1000Genomes
ENSVATH01010515 90 G>D No 1000Genomes
ENSVATH00004742 94 F>V No 1000Genomes
tmp_1_1014520_C_T 114 P>S No 1000Genomes
tmp_1_1014527_G_A 116 R>H No 1000Genomes
tmp_1_1014833_C_G 144 Q>E No 1000Genomes
ENSVATH04515768 147 S>N No 1000Genomes
tmp_1_1014855_A_G 151 D>G No 1000Genomes
tmp_1_1015001_C_G 174 P>A No 1000Genomes
ENSVATH01010527 200 G>S No 1000Genomes
tmp_1_1015242_A_C 205 M>L No 1000Genomes
ENSVATH01010528 221 S>N No 1000Genomes
tmp_1_1015428_G_C 226 A>P No 1000Genomes
ENSVATH01010535 227 D>N No 1000Genomes
ENSVATH13851645 230 P>S No 1000Genomes
ENSVATH10546128 250 E>K No 1000Genomes
tmp_1_1015684_C_T 256 A>V No 1000Genomes
ENSVATH04515780 271 G>R No 1000Genomes
ENSVATH04515781 286 I>N No 1000Genomes
tmp_1_1015773_A_G 286 I>V No 1000Genomes
tmp_1_1015815_A_G 300 K>E No 1000Genomes
ENSVATH04515785 345 I>V No 1000Genomes
ENSVATH01010545 364 K>N No 1000Genomes
tmp_1_1016376_A_C 365 M>L No 1000Genomes
tmp_1_1016379_A_T 366 S>C No 1000Genomes
tmp_1_1016380_G_C 366 S>T No 1000Genomes
tmp_1_1016395_T_C 371 V>A No 1000Genomes
ENSVATH04515795 424 A>T No 1000Genomes
tmp_1_1016904_C_A 426 L>I No 1000Genomes
tmp_1_1016938_T_G 437 M>R No 1000Genomes
tmp_1_1017111_C_A 459 N>K No 1000Genomes
tmp_1_1017170_T_C 479 F>S No 1000Genomes
ENSVATH01010557 482 R>H No 1000Genomes
tmp_1_1017352_G_T 490 L>F No 1000Genomes
tmp_1_1017362_G_A 494 D>N No 1000Genomes
ENSVATH04515799 499 R>I No 1000Genomes
tmp_1_1017410_G_A 510 V>I No 1000Genomes
ENSVATH10546435 522 D>G No 1000Genomes
ENSVATH01010560 526 E>G No 1000Genomes
tmp_1_1017458_G_C 526 E>Q No 1000Genomes

No associated diseases with Q84JI6

3 regional properties for Q84JI6

Type Name Position InterPro Accession
domain EF-hand domain 310 - 416 IPR002048
binding_site EF-Hand 1, calcium-binding site 394 - 406 IPR018247
domain PP2A regulatory subunit B'', EF-hand domain 206 - 295 IPR041534

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
protein phosphatase type 2A complex A protein complex that has protein serine/threonine phosphatase activity that is polycation-stimulated (PCS), being directly stimulated by protamine, polylysine, or histone H1; it constitutes a subclass of several enzymes activated by different histones and polylysine, and consists of catalytic, scaffolding, and regulatory subunits. The catalytic and scaffolding subunits form the core enzyme, and the holoenzyme also includes the regulatory subunit.

2 GO annotations of molecular function

Name Definition
calcium ion binding Binding to a calcium ion (Ca2+).
protein phosphatase regulator activity Binds to and modulates the activity of a protein phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a protein substrate molecule.

1 GO annotations of biological process

Name Definition
protein dephosphorylation The process of removing one or more phosphoric residues from a protein.

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9SLI8 B''DELTA Probable serine/threonine protein phosphatase 2A regulatory subunit B''delta Arabidopsis thaliana (Mouse-ear cress) PR
Q9XGR4 B''ALPHA Serine/threonine protein phosphatase 2A regulatory subunit B''alpha Arabidopsis thaliana (Mouse-ear cress) PR
Q803V3 ppp2r3c Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma Danio rerio (Zebrafish) (Brachydanio rerio) PR
10 20 30 40 50 60
MDIDGVDDDL HILDPELLQL PGLSPSPLKP TSLIADDLFS QWLSLPETAT LVKSLIDDAK
70 80 90 100 110 120
SGTPTNKSKN LPSVFLSSST PPLSPRSSSG SPRFSRQRTS PPSLHSPLRS LKEPKRQLIP
130 140 150 160 170 180
QFYYQHGRPP AKELKEQCLS MVDQVFSNYI DGLHVDEFKS ITKQVCKLPS FLSPALFRKI
190 200 210 220 230 240
DPNCTDIVTR DAFIKYWIDG NMLTMDTASQ IYNILRQQGC SYLRQADFKP VLDELLATHP
250 260 270 280 290 300
GLEFLRTISE FQERYAETVI YRIFYYINRS GTGCLTLREL RRGNLIAAMQ QLDEEDDINK
310 320 330 340 350 360
IIRYFSYEHF YVIYCKFWEL DGDHDCFIDK DNLIKYGNNA LTYRIVDRIF SQIPRKFTSK
370 380 390 400 410 420
VEGKMSYEDF VYFILAEEDK SSEPSLEYWF KCVDLDGNGV ITSNEMQFFF EEQLHRMECI
430 440 450 460 470 480
TQEAVLFSDI LCQIIDMIGP EKENCITLQD LKGSKLSANV FNILFNLNKF MAFETRDPFL
490 500 510 520
IRQEREDPNL TEWDRFAQRE YARLSMEEDV DEVSNGSADV WDEPLEPPF