Q803V3

PR
Gene name
ppp2r3c (zgc:55473)
Protein name
Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma
Names
Species
Danio rerio (Zebrafish) (Brachydanio rerio)
KEGG Pathway
dre:393100
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-74 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q803V3

Entry ID Method Resolution Chain Position Source
AF-Q803V3-F1 Predicted AlphaFoldDB

No variants for Q803V3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q803V3

No associated diseases with Q803V3

2 regional properties for Q803V3

Type Name Position InterPro Accession
binding_site EF-Hand 1, calcium-binding site 289 - 301 IPR018247
domain PP2A regulatory subunit B'', EF-hand domain 186 - 261 IPR041534

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
centrosome A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

1 GO annotations of molecular function

Name Definition
metal ion binding Binding to a metal ion.

6 GO annotations of biological process

Name Definition
B cell homeostasis The process of regulating the proliferation and elimination of B cells such that the total number of B cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.
cortical cytoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures in the cell cortex, i.e. just beneath the plasma membrane.
microtubule cytoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.
positive regulation of B cell differentiation Any process that activates or increases the frequency, rate or extent of B cell differentiation.
regulation of dephosphorylation Any process that modulates the frequency, rate or extent of removal of phosphate groups from a molecule.
T cell homeostasis The process of regulating the proliferation and elimination of T cells such that the total number of T cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q84JI6 B''EPSILON Probable serine/threonine protein phosphatase 2A regulatory subunit B''epsilon Arabidopsis thaliana (Mouse-ear cress) PR
Q9SLI8 B''DELTA Probable serine/threonine protein phosphatase 2A regulatory subunit B''delta Arabidopsis thaliana (Mouse-ear cress) PR
Q9XGR4 B''ALPHA Serine/threonine protein phosphatase 2A regulatory subunit B''alpha Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MANDITAHWK DLLRKRLASL KPDGRTEEEK KAEESELFSK YYTEWKGGEK GEDDSFKHIP
70 80 90 100 110 120
RFYYRLPAED EVLMQKLREE SRAVFLQRKS RELLDNEELQ NLWFLLDKHQ VPPTTGDEAM
130 140 150 160 170 180
ISYESFLKVG EKAGTKCKLF FTARVYAKLL HNDPYGRISI MQFFNYVMRK VWLHQTRIGL
190 200 210 220 230 240
SLYDVAGQGY LRESDLENYI LELIPTLPQL DGLEKSFYSF YVCTAVRKFF FFLDPLHTGK
250 260 270 280 290 300
IKIQDILACS FLDDLLELRD EELSKESQES NWFSAPSALR VYGQYLNLDK DHNGMLSKEE
310 320 330 340 350 360
LSRYGTGTLT SVFLDRVYQA CLTYDGEMDY KTYLDFVLAL ENRKEPAALQ YIFKLLDMEN
370 380 390 400 410 420
KGYLNVFALN YFFRAIQEQM KIHGQEPVSF QDVKDEIFDM VKPKDPYKIT LQDLVNSGQG
430 440 450
DTVSSILIDL NGFWTYENRE VLVANDTDSN AADLDDT