AiPD: Autoinhibited Protein Database

Gene name	Gimap8 (Ian9)
Protein name	GTPase IMAP family member 8
Names	mGIMAP8, Immune-associated nucleotide-binding protein 9, IAN-9, Immunity-associated protein 8
Species	Mus musculus (Mouse)
KEGG Pathway	mmu:243374
EC number
Protein Class

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

1-76 (Predicted disordered autoinhibitory region) PR

1-76 (Predicted disordered autoinhibitory region)

cis-regPred

No accessory elements

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q75N62-F1	Predicted				AlphaFoldDB

Variant ID(s)	Position	Change	Diseaes Association	Provenance
rs3388829950	21	E>G	No	EVA
rs3388832566	30	P>L	No	EVA
rs222063591	35	G>D	No	EVA
rs236877031	45	G>E	No	EVA
rs3388832609	61	K>N	No	EVA
rs3388815425	80	D>G	No	EVA
rs223237404	85	D>N	No	EVA
rs3388832572	111	L>R	No	EVA
rs243267962	113	C>Y	No	EVA
rs37161607	114	S>P	No	EVA
rs231672289	129	A>D	No	EVA
rs3388823845	153	E>D	No	EVA
rs3388832608	173	R>L	No	EVA
rs37385477	236	E>G	No	EVA
rs260541985	248	G>E	No	EVA
rs242294100	266	S>P	No	EVA
rs3388794659	268	K>N	No	EVA
rs256938500	281	D>E	No	EVA
rs29977715	319	R>Q	No	EVA
rs232321658	395	K>E	No	EVA
rs245256670	409	D>A	No	EVA
rs217323903	411	A>V	No	EVA
rs39970421	413	D>N	No	EVA
rs37594587	414	K>T	No	EVA
rs3388826275	426	T>S	No	EVA
rs211802088	434	A>T	No	EVA
rs3388818435	460	V>E	No	EVA
rs3388813010	464	S>G	No	EVA
rs3388828756	503	S>C	No	EVA
rs3388835984	524	Q>R	No	EVA
rs3388826530	544	P>H	No	EVA
rs239428306	549	E>K	No	EVA
rs3388807927	566	V>I	No	EVA
rs3412902676	568	V>L	No	EVA
rs3396567191	572	G>*	No	EVA
rs3396567191	573	R>*	No	EVA
rs222000094	616	T>I	No	EVA
rs3388832536	618	N>S	No	EVA
rs3388823794	623	A>T	No	EVA
rs3388826591	640	N>Y	No	EVA
rs3388829887	643	T>N	No	EVA
rs236799235	653	G>D	No	EVA
rs236799235	653	G>V	No	EVA
rs3388794667	658	A>T	No	EVA
rs3388828349	660	S>G	No	EVA
rs37474540	668	H>R	No	EVA
rs3388794728	673	V>M	No	EVA
rs230915836	683	I>F	No	EVA
rs3388829955	685	M>L	No	EVA
rs255030569	686	A>T	No	EVA

Type	Name	Position	InterPro Accession
No domain, repeats, and functional sites for Q75N62

		Description
EC Number
Subcellular Localization	Endoplasmic reticulum Golgi apparatus Mitochondrion Cytoplasm, cytosol
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

Name	Definition
cytosol	The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
endoplasmic reticulum	The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
Golgi apparatus	A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways.
mitochondrion	A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

Name	Definition
GTP binding	Binding to GTP, guanosine triphosphate.

Name	Definition
regulation of T cell apoptotic process	Any process that modulates the occurrence or rate of T cell death by apoptotic process.

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
Q4KLG2	Gimap8	GTPase IMAP family member 8	Rattus norvegicus (Rat)	PR
P54120	IAN8	Immune-associated nucleotide-binding protein 8	Arabidopsis thaliana (Mouse-ear cress)	PR