Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6R8G4
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6R8G4-F1 | Predicted | AlphaFoldDB |
No variants for Q6R8G4
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q6R8G4 | |||||
No associated diseases with Q6R8G4
5 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| Golgi apparatus | A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
| trans-Golgi network | The network of interconnected tubular and cisternal structures located within the Golgi apparatus on the side distal to the endoplasmic reticulum, from which secretory vesicles emerge. The trans-Golgi network is important in the later stages of protein secretion where it is thought to play a key role in the sorting and targeting of secreted proteins to the correct destination. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| inositol hexakisphosphate binding | Binding to inositol hexakisphosphate. |
| phosphate ion transmembrane transporter activity | Enables the transfer of phosphate (PO4 3-) ions from one side of a membrane to the other. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| cellular response to phosphate starvation | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of phosphate. |
| phosphate ion transport | The directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MKFGKDFSSE | WQQAYVDYKY | LKTLVKDINR | FKRKTNLHGG | QISLSSTVLE | IEDGITTATI |
| 70 | 80 | 90 | 100 | 110 | 120 |
| QVSSTASQRY | ETTFLMTAEK | GGEYELVFFR | RLDDEFNKVE | KFYREKVDEV | VKEAAVLNKQ |
| 130 | 140 | 150 | 160 | 170 | 180 |
| MDALIAFRLK | MKEESTVEMA | RFALHGVVSP | AELAKNPSMK | VHMEAIEEGG | SSRAGRRSDE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DDYYTDEEDH | NDVFFTPANN | LSKMKSSSSA | FIEVLDSIKI | NNTKEALQSN | TKSVLKVSNH |
| 250 | 260 | 270 | 280 | 290 | 300 |
| TELKFSRDNL | RKIEEKLICA | FVEFHRKLWY | LKSYSFLNVL | ALSKILTKYD | KITSRDAAKS |
| 310 | 320 | 330 | 340 | 350 | 360 |
| YMKMVDKSCL | GSSDEVMKLM | ENVEATFIKQ | FTNGNRTKGM | NILRPKPKRE | RHRLTFSTGF |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LGGCMFSLIV | ALVAIVRTRN | ILQDDGQKQY | MNTMFPLYSL | FGFIMLHMTM | YAANIYFWRQ |
| 430 | 440 | 450 | 460 | 470 | 480 |
| YRVNYSFIFG | FKQGTELGYK | QVLFVGFSIG | ALALLCVLAN | LDMETDPKTK | DYQALTELLP |
| 490 | 500 | 510 | 520 | 530 | 540 |
| LFLLIAMFVV | LVVPFNIFYR | SSRFFFLTTL | FHMLAAPLYK | VTLPDFFLAD | QLCSQAQTLR |
| 550 | 560 | 570 | 580 | 590 | 600 |
| SIEFYICYYG | WGDFKQRKNT | CKDSQVFNTF | LFIVSAFPFF | SRFLQCMRRM | LEEKNIEQGY |
| 610 | 620 | 630 | 640 | 650 | 660 |
| NGFKYIVIVV | AVCLGMAYEV | DDEKDRQIIW | RLLGGITSAM | AVVFCTYWDL | VYDWGLLNRT |
| 670 | 680 | 690 | 700 | 710 | 720 |
| SKNPWLRDNL | LIPHKEVYVL | AMILNVVLRF | AWMQTVLDFK | FESIHTQTVV | AVVASLEIIR |
| 730 | 740 | 750 | |||
| RGIWNFFRLE | NEHLNNVGKY | RAFKAVSLPF | NYEVDH |