Q6R8G2
PR
Gene name |
PHO1-H8 (At1g35350, T9I1.12) |
Protein name |
Phosphate transporter PHO1 homolog 8 |
Names |
Protein PHO1 homolog 8, AtPHO1H8 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT1G35350 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6R8G2
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6R8G2-F1 | Predicted | AlphaFoldDB |
89 variants for Q6R8G2
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH01192565 | 9 | A>S | No | 1000Genomes | |
| tmp_1_12984526_T_C | 20 | M>V | No | 1000Genomes | |
| tmp_1_12984499_G_T | 29 | L>I | No | 1000Genomes | |
| ENSVATH04742581 | 38 | R>I | No | 1000Genomes | |
| ENSVATH01192564 | 40 | E>A | No | 1000Genomes | |
| tmp_1_12984454_C_G | 44 | V>L | No | 1000Genomes | |
| ENSVATH01192561 | 57 | G>V | No | 1000Genomes | |
| tmp_1_12984400_A_G | 62 | Y>H | No | 1000Genomes | |
| ENSVATH01192560 | 74 | H>Q | No | 1000Genomes | |
| ENSVATH01192559 | 77 | M>L | No | 1000Genomes | |
| tmp_1_12984294_A_G | 97 | V>A | No | 1000Genomes | |
| ENSVATH00066925 | 100 | V>A | No | 1000Genomes | |
| ENSVATH04742578 | 101 | G>R | No | 1000Genomes | |
| tmp_1_12984268_G_A | 106 | L>F | No | 1000Genomes | |
| tmp_1_12984233_A_C | 117 | D>E | No | 1000Genomes | |
| ENSVATH14092783 | 124 | R>Q | No | 1000Genomes | |
| tmp_1_12984206_G_T | 126 | N>K | No | 1000Genomes | |
| ENSVATH04742574 | 131 | V>E | No | 1000Genomes | |
| ENSVATH14092782 | 132 | K>M | No | 1000Genomes | |
| ENSVATH12966303 | 132 | K>N | No | 1000Genomes | |
| ENSVATH12966299 | 178 | G>A | No | 1000Genomes | |
| tmp_1_12983949_C_A | 184 | E>D | No | 1000Genomes | |
| tmp_1_12983951_C_T | 184 | E>K | No | 1000Genomes | |
| ENSVATH04742571 | 195 | N>Y | No | 1000Genomes | |
| ENSVATH12966297 | 204 | A>V | No | 1000Genomes | |
| ENSVATH04742570 | 205 | P>R | No | 1000Genomes | |
| ENSVATH14092780 | 207 | A>S | No | 1000Genomes | |
| tmp_1_12983857_C_T | 215 | R>K | No | 1000Genomes | |
| tmp_1_12983846_T_G | 219 | N>H | No | 1000Genomes | |
| ENSVATH12966296 | 220 | Q>H | No | 1000Genomes | |
| tmp_1_12983834_G_A | 223 | P>S | No | 1000Genomes | |
| ENSVATH04742569 | 228 | R>K | No | 1000Genomes | |
| tmp_1_12983794_T_G | 236 | K>T | No | 1000Genomes | |
| tmp_1_12983786_T_G | 239 | I>L | No | 1000Genomes | |
| tmp_1_12983761_T_C | 247 | K>R | No | 1000Genomes | |
| ENSVATH04742567 | 259 | E>D | No | 1000Genomes | |
| tmp_1_12983720_A_T | 261 | Y>N | No | 1000Genomes | |
| ENSVATH14092778 | 268 | K>N | No | 1000Genomes | |
| ENSVATH01192555 | 268 | K>Q | No | 1000Genomes | |
| ENSVATH14092777 | 296 | L>S | No | 1000Genomes | |
| ENSVATH12966282 | 298 | M>L | No | 1000Genomes | |
| tmp_1_12983440_C_T | 300 | M>I | No | 1000Genomes | |
| tmp_1_12983442_T_G | 300 | M>L | No | 1000Genomes | |
| ENSVATH01192549 | 305 | Y>F | No | 1000Genomes | |
| tmp_1_12983302_C_G | 316 | M>I | No | 1000Genomes | |
| ENSVATH00066920 | 325 | E>D | No | 1000Genomes | |
| tmp_1_12983274_G_T | 326 | H>N | No | 1000Genomes | |
| ENSVATH12966264 | 332 | R>* | No | 1000Genomes | |
| tmp_1_12982966_A_G | 362 | V>A | No | 1000Genomes | |
| tmp_1_12982916_C_A | 379 | G>C | No | 1000Genomes | |
| ENSVATH04742549 | 380 | A>E | No | 1000Genomes | |
| ENSVATH12966204 | 380 | A>S | No | 1000Genomes | |
| ENSVATH14092726 | 382 | G>R | No | 1000Genomes | |
| tmp_1_12982889_C_G | 388 | E>Q | No | 1000Genomes | |
| ENSVATH12966200 | 400 | V>A | No | 1000Genomes | |
| ENSVATH12966200 | 400 | V>G | No | 1000Genomes | |
| tmp_1_12982665_C_T | 432 | E>K | No | 1000Genomes | |
| tmp_1_12982644_G_T | 439 | L>M | No | 1000Genomes | |
| ENSVATH04742547 | 449 | A>S | No | 1000Genomes | |
| ENSVATH04742546 | 451 | C>S | No | 1000Genomes | |
| tmp_1_12982414_T_G | 486 | I>L | No | 1000Genomes | |
| tmp_1_12982394_G_C | 492 | N>K | No | 1000Genomes | |
| tmp_1_12982386_T_G | 495 | Y>S | No | 1000Genomes | |
| ENSVATH01192532 | 504 | M>I | No | 1000Genomes | |
| ENSVATH04742538 | 565 | T>S | No | 1000Genomes | |
| ENSVATH14092650 | 572 | V>A | No | 1000Genomes | |
| tmp_1_12981916_T_A | 586 | L>F | No | 1000Genomes | |
| ENSVATH12966098 | 590 | K>Q | No | 1000Genomes | |
| ENSVATH00066911 | 592 | V>L | No | 1000Genomes | |
| ENSVATH01192511 | 599 | L>I | No | 1000Genomes | |
| ENSVATH04742536 | 606 | V>L | No | 1000Genomes | |
| tmp_1_12981837_C_T | 613 | A>T | No | 1000Genomes | |
| tmp_1_12981818_C_T | 619 | G>E | No | 1000Genomes | |
| tmp_1_12981792_C_T | 628 | V>I | No | 1000Genomes | |
| ENSVATH14092649 | 644 | Y>F | No | 1000Genomes | |
| tmp_1_12981722_C_T | 651 | R>K | No | 1000Genomes | |
| ENSVATH01192503 | 654 | K>I | No | 1000Genomes | |
| ENSVATH04742534 | 654 | K>Q | No | 1000Genomes | |
| tmp_1_12981686_A_G | 663 | V>A | No | 1000Genomes | |
| ENSVATH12966014 | 665 | H>Q | No | 1000Genomes | |
| ENSVATH00066909 | 666 | K>R | No | 1000Genomes | |
| tmp_1_12981535_A_C | 687 | V>G | No | 1000Genomes | |
| ENSVATH14092648 | 701 | V>I | No | 1000Genomes | |
| tmp_1_12981491_C_A | 702 | A>S | No | 1000Genomes | |
| tmp_1_12981458_C_T | 713 | G>S | No | 1000Genomes | |
| ENSVATH04742531 | 730 | K>N | No | 1000Genomes | |
| tmp_1_12981267_T_C | 747 | E>G | No | 1000Genomes | |
| tmp_1_12981258_T_G | 750 | D>A | No | 1000Genomes | |
| tmp_1_12981254_A_T | 751 | S>R | No | 1000Genomes |
No associated diseases with Q6R8G2
5 regional properties for Q6R8G2
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Zinc finger, LIM-type | 226 - 285 | IPR001781-1 |
| domain | Zinc finger, LIM-type | 286 - 343 | IPR001781-2 |
| domain | Zinc finger, LIM-type | 344 - 403 | IPR001781-3 |
| domain | Zinc finger, LIM-type | 404 - 461 | IPR001781-4 |
| domain | Paxillin/TGFB1I1, LIM domain 1 | 228 - 280 | IPR047075 |
5 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| Golgi apparatus | A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
| trans-Golgi network | The network of interconnected tubular and cisternal structures located within the Golgi apparatus on the side distal to the endoplasmic reticulum, from which secretory vesicles emerge. The trans-Golgi network is important in the later stages of protein secretion where it is thought to play a key role in the sorting and targeting of secreted proteins to the correct destination. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| inositol hexakisphosphate binding | Binding to inositol hexakisphosphate. |
| phosphate ion transmembrane transporter activity | Enables the transfer of phosphate (PO4 3-) ions from one side of a membrane to the other. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| cellular response to phosphate starvation | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of phosphate. |
| phosphate ion transport | The directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MKFGKEYVAQ | MIPEWQQAYM | DYTCLKTILR | EIKTSQKRSE | SQGVLKRKLS | GRRNFSGLTK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| RYSRTFSSRD | LENHDIMVHA | TTGDDGFEKY | ETTILKVSEV | GRESELVFFK | TLDLEFDKVN |
| 130 | 140 | 150 | 160 | 170 | 180 |
| RFYRSNVEEL | VKEAVVLNRQ | MDALIAYRIK | LDQPSTSWSC | SETVSVDINA | LDSKEQKGKT |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LAEEMGIKVE | ENVSNGGDST | KETAPEALSV | LDRIRLNKNQ | ENPLSTIRNV | LKLSNKEDIK |
| 250 | 260 | 270 | 280 | 290 | 300 |
| FTKENLKKIE | ERLKNVFIEF | YRKLRHLKNY | SFLNTLAISK | IMKKYDKIAL | RNAAKLYMEM |
| 310 | 320 | 330 | 340 | 350 | 360 |
| VDKSYLTSSD | EINKLMLRVE | SIFVEHFAGS | NRSKGMNLLR | PKVTKEKHRI | TFSTGFFVGC |
| 370 | 380 | 390 | 400 | 410 | 420 |
| TVSLVIALGL | FIHARNIMGA | VGHKLYMETM | FPLYSLFAFV | VLHMIMYASN | IYFWKRYRVN |
| 430 | 440 | 450 | 460 | 470 | 480 |
| YPFIFGFKEG | TELGYGHVLL | LSFGLGTLAL | CAVLVNMDME | MDPNTNDYKT | ITELVPLFVV |
| 490 | 500 | 510 | 520 | 530 | 540 |
| ALVIAISVCP | FNIFYRSSRF | FFLMVLFRCI | AAPLYKVNLP | DFFLADQLTS | QVQALRSLEF |
| 550 | 560 | 570 | 580 | 590 | 600 |
| YICYYGWGDF | KQRQSTCKSS | DVYSTFYFIV | AVIPYWSRFL | QCVRRLIEEK | DVSQGFNALK |
| 610 | 620 | 630 | 640 | 650 | 660 |
| YLLTIVAVCL | RTAFSINRGN | DWKIAAWVFS | GLATFYGTYW | DIVYDWGLLH | RPSKSWLREK |
| 670 | 680 | 690 | 700 | 710 | 720 |
| LLVPHKSVYY | VAMVVNVVLR | LAWLQTVLDF | NISFLHRETM | VALIAILEII | RRGIWNFFRL |
| 730 | 740 | 750 | |||
| ENEHLNNVGK | FRAFKSVPLP | FNYDEEEDRD | S |