Q6PC55
Gene name |
gid8a (twa1) |
Protein name |
Glucose-induced degradation protein 8-A homolog |
Names |
Two hybrid-associated protein 1 with RanBPM, Twa1 |
Species |
Danio rerio (Zebrafish) (Brachydanio rerio) |
KEGG Pathway |
dre:393685 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6PC55
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6PC55-F1 | Predicted | AlphaFoldDB |
No variants for Q6PC55
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q6PC55 | |||||
No associated diseases with Q6PC55
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| determination of dorsal identity | Determination of the identity of part of an organism or organ where those parts are of the type that occur in the dorsal region. Identity is considered to be the aggregate of characteristics by which a structure is recognized. |
| positive regulation of canonical Wnt signaling pathway | Any process that increases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. |
| proteasome-mediated ubiquitin-dependent protein catabolic process | The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome. |
| Wnt signaling pathway | The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in cell state. |
4 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q32L52 | GID8 | Glucose-induced degradation protein 8 homolog | Bos taurus (Bovine) | PR |
| Q5ZKQ7 | GID8 | Glucose-induced degradation protein 8 homolog | Gallus gallus (Chicken) | PR |
| Q9NWU2 | GID8 | Glucose-induced degradation protein 8 homolog | Homo sapiens (Human) | PR |
| Q9D7M1 | Gid8 | Glucose-induced degradation protein 8 homolog | Mus musculus (Mouse) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSYSEKPEDI | TKEEWMDKLN | NVHIQRADMN | RLIMNYLVTE | GFKEAAEKFR | MESGIEPNVD |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LDSLDERIKI | REMVLKGQIQ | EAIALINSLH | PELLDTNRYL | YFHLQQQHLI | ELIRLRETEA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ALEFAQSQLA | EQGEESRECL | TEMERTLALL | AFDNPEESPF | GDLLNMMQRQ | KVWSEVNQAV |
| 190 | 200 | 210 | 220 | ||
| LDYENRESTP | KLAKLLKLLL | WAQNELDQKK | VKYSRMTDLS | KGTIEDPK |