Q6P1U7
Gene name |
anp32b (TGas062k23.1) |
Protein name |
Acidic leucine-rich nuclear phosphoprotein 32 family member B |
Names |
|
Species |
Oryza sativa subsp japonica (Rice) |
KEGG Pathway |
xtr:395041 |
EC number |
2.7.12.2: Dual-specificity kinases (those acting on Ser/Thr and Tyr residues) |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
1-165 (Leucine-rich region) |
Relief mechanism |
PTM, Others |
Assay |
|
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6P1U7
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6P1U7-F1 | Predicted | AlphaFoldDB |
No variants for Q6P1U7
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q6P1U7 | |||||
No associated diseases with Q6P1U7
9 regional properties for Q6P1U7
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Protein kinase domain | 134 - 392 | IPR000719 |
| domain | EF-hand domain | 435 - 506 | IPR002048-1 |
| domain | EF-hand domain | 507 - 576 | IPR002048-2 |
| active_site | Serine/threonine-protein kinase, active site | 254 - 266 | IPR008271 |
| binding_site | Protein kinase, ATP binding site | 140 - 167 | IPR017441 |
| binding_site | EF-Hand 1, calcium-binding site | 448 - 460 | IPR018247-1 |
| binding_site | EF-Hand 1, calcium-binding site | 484 - 496 | IPR018247-2 |
| binding_site | EF-Hand 1, calcium-binding site | 520 - 532 | IPR018247-3 |
| binding_site | EF-Hand 1, calcium-binding site | 554 - 566 | IPR018247-4 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.7.12.2 | Dual-specificity kinases (those acting on Ser/Thr and Tyr residues) |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| histone binding | Binding to a histone, any of a group of water-soluble proteins found in association with the DNA of eukaryotic or archaeal chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in gene regulation and DNA replication. They may be chemically modified (methylated, acetlyated and others) to regulate gene transcription. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| regulation of apoptotic process | Any process that modulates the occurrence or rate of cell death by apoptotic process. |
18 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P51122 | ANP32A | Acidic leucine-rich nuclear phosphoprotein 32 family member A | Bos taurus (Bovine) | SS |
| Q3SZC6 | ANP32B | Acidic leucine-rich nuclear phosphoprotein 32 family member B | Bos taurus (Bovine) | SS |
| Q5F4A3 | ANP32E | Acidic leucine-rich nuclear phosphoprotein 32 family member E | Gallus gallus (Chicken) | SS |
| Q5ZMN0 | ANP32B | Acidic leucine-rich nuclear phosphoprotein 32 family member B | Gallus gallus (Chicken) | SS |
| Q9V895 | Anp32a | Acidic leucine-rich nuclear phosphoprotein 32 family member A | Drosophila melanogaster (Fruit fly) | SS |
| Q9BTT0 | ANP32E | Acidic leucine-rich nuclear phosphoprotein 32 family member E | Homo sapiens (Human) | SS |
| P39687 | ANP32A | Acidic leucine-rich nuclear phosphoprotein 32 family member A | Homo sapiens (Human) | EV |
| Q92688 | ANP32B | Acidic leucine-rich nuclear phosphoprotein 32 family member B | Homo sapiens (Human) | SS |
| P97822 | Anp32e | Acidic leucine-rich nuclear phosphoprotein 32 family member E | Mus musculus (Mouse) | SS |
| O35381 | Anp32a | Acidic leucine-rich nuclear phosphoprotein 32 family member A | Mus musculus (Mouse) | SS |
| Q9EST5 | Anp32b | Acidic leucine-rich nuclear phosphoprotein 32 family member B | Mus musculus (Mouse) | SS |
| Q5XIE0 | Anp32e | Acidic leucine-rich nuclear phosphoprotein 32 family member E | Rattus norvegicus (Rat) | SS |
| P49911 | Anp32a | Acidic leucine-rich nuclear phosphoprotein 32 family member A | Rattus norvegicus (Rat) | SS |
| Q9EST6 | Anp32b | Acidic leucine-rich nuclear phosphoprotein 32 family member B | Rattus norvegicus (Rat) | SS |
| Q7Y180 | Os03g0668900 | Acidic leucine-rich nuclear phosphoprotein 32-related protein 2 | Oryza sativa subsp. japonica (Rice) | SS |
| Q9SCQ7 | At3g50690 | Acidic leucine-rich nuclear phosphoprotein 32-related protein | Arabidopsis thaliana (Mouse-ear cress) | SS |
| Q6NUW5 | anp32e | Acidic leucine-rich nuclear phosphoprotein 32 family member E | Danio rerio (Zebrafish) (Brachydanio rerio) | SS |
| Q7ZUP0 | anp32a | Acidic leucine-rich nuclear phosphoprotein 32 family member A | Danio rerio (Zebrafish) (Brachydanio rerio) | SS |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MRGKKPHKEL | KLSVPAQETP | VDKFLTASGT | FKDGELRLNQ | RGLQLISEET | ADEPQSTNLK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VEDVQLSMDD | LEMIQVIGKG | SGGIVQLVRH | KWVGTLYALK | GIQMNIQEAV | RKQIVQELKI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| NQATQNAHIV | LCHQSFYHNG | VIYLVLEYMD | RGSLADIIKQ | VKTILEPYLA | VLCKQVLEGL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LYLHHERHVI | HRDIKPSNLL | VNRKGEVKIT | DFGVSAVLAS | SMGQRDTFVG | TYNYMAPERI |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SGSSYDYKSD | IWSLGLVILE | CAIGRFPYIP | SEGEGWLSFY | ELLEAIVDQP | PPSAPADQFS |
| 310 | 320 | 330 | 340 | 350 | |
| PEFCAFISSC | IQKDPAERMS | ASELLNHPFI | KKFEDKDLDL | RILVESLEPP | MNISE |