Q6NSI4
PR
Gene name |
RADX |
Protein name |
RPA-related protein RADX |
Names |
RPA-related and RAD51-antagonist, X-chromosome |
Species |
Homo sapiens (Human) |
KEGG Pathway |
hsa:55086 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
3 structures for Q6NSI4
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 8U5Y | EM | 301 A | A/B/C | 1-855 | PDB |
| 8U61 | EM | 400 A | A/B/C/D | 1-855 | PDB |
| AF-Q6NSI4-F1 | Predicted | AlphaFoldDB |
378 variants for Q6NSI4
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
|
CA10482095 rs199854559 |
2 | S>C | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA10482096 rs771275007 |
3 | G>A | No |
ClinGen ExAC gnomAD |
|
|
CA10482097 rs376438253 |
5 | S>P | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1336202093 CA413877610 |
6 | G>E | No |
ClinGen gnomAD |
|
|
CA413877628 rs1464522656 |
9 | E>A | No |
ClinGen TOPMed gnomAD |
|
|
rs774119956 CA10482100 |
12 | P>S | No |
ClinGen ExAC gnomAD |
|
|
CA413877653 rs1440891234 |
13 | S>L | No |
ClinGen gnomAD |
|
|
rs1603030980 CA413877657 |
14 | H>Y | No |
ClinGen Ensembl |
|
|
rs1569421620 CA413877687 |
18 | D>E | No |
ClinGen Ensembl |
|
|
CA413877703 rs1239099445 |
20 | P>R | No |
ClinGen TOPMed |
|
|
rs767410173 CA10482102 |
21 | N>Y | No |
ClinGen ExAC |
|
|
CA10482103 rs749942009 |
24 | R>K | No |
ClinGen ExAC gnomAD |
|
|
rs1167035780 CA413877740 |
26 | R>W | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs765991272 CA10482106 |
30 | P>A | No |
ClinGen ExAC gnomAD |
|
|
COSM1464656 CA10482107 rs370255784 |
30 | P>L | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ESP ExAC NCI-TCGA gnomAD |
|
CA10482105 rs765991272 |
30 | P>S | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 31 | G>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA413877772 rs1301170224 |
32 | G>R | No |
ClinGen TOPMed |
|
|
rs1393926876 CA413877794 |
35 | R>Q | No |
ClinGen gnomAD |
|
|
rs909164266 CA333408955 |
41 | G>E | No |
ClinGen TOPMed |
|
|
rs1303992225 CA413877835 |
42 | P>A | No |
ClinGen TOPMed |
|
|
rs758933008 CA10482110 |
44 | S>P | No |
ClinGen ExAC gnomAD |
|
|
CA10482112 rs747057484 |
47 | Q>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs771186847 CA10482113 |
49 | V>A | No |
ClinGen ExAC |
|
| TCGA novel | 50 | L>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs201142543 CA10482115 |
51 | E>G | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs781519814 COSM122435 CA10482114 |
51 | E>Q | upper_aerodigestive_tract [Cosmic] | No |
ClinGen cosmic curated ExAC gnomAD |
|
CA10482116 rs768275039 |
52 | Q>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs927179757 CA333408965 |
53 | I>T | No |
ClinGen Ensembl |
|
|
rs774178715 CA10482117 |
55 | D>V | No |
ClinGen ExAC gnomAD |
|
|
CA413877936 rs1258425090 |
57 | P>S | No |
ClinGen TOPMed gnomAD |
|
|
CA333408969 rs969190349 |
58 | R>C | No |
ClinGen TOPMed gnomAD |
|
|
CA413877940 rs969190349 |
58 | R>S | No |
ClinGen TOPMed gnomAD |
|
|
CA10482119 rs772012236 |
60 | C>S | No |
ClinGen ExAC gnomAD |
|
|
rs773071044 CA10482120 |
61 | V>I | No |
ClinGen ExAC gnomAD |
|
|
CA413877969 rs1434692724 |
62 | T>I | No |
ClinGen TOPMed |
|
|
rs1159282722 CA413877967 |
62 | T>S | No |
ClinGen gnomAD |
|
|
rs760128227 CA10482121 |
63 | P>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1487127109 CA413877979 |
64 | S>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
| TCGA novel | 64 | S>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA10482122 rs765905243 |
74 | V>I | No |
ClinGen ExAC TOPMed |
|
|
rs1603031164 CA413878046 |
75 | Q>R | No |
ClinGen Ensembl |
|
|
CA413878129 rs1437813592 |
87 | V>L | No |
ClinGen gnomAD |
|
|
CA333408983 rs756257741 |
90 | P>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
|
CA333408985 rs199638136 |
92 | L>R | No |
ClinGen 1000Genomes TOPMed gnomAD |
|
|
CA413878273 rs1310535411 |
108 | C>R | No |
ClinGen gnomAD |
|
|
rs1233601738 CA413878284 |
109 | Y>C | No |
ClinGen gnomAD |
|
|
rs1350296819 CA413878303 |
112 | P>H | No |
ClinGen gnomAD |
|
|
rs758731712 CA10482127 |
112 | P>S | No |
ClinGen ExAC gnomAD |
|
|
CA413878312 rs1272203739 CA413878313 |
113 | S>R | No |
ClinGen TOPMed gnomAD |
|
|
CA10482128 rs764643180 |
115 | N>S | No |
ClinGen ExAC gnomAD |
|
|
CA333408997 rs909876612 |
118 | V>I | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 124 | K>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1042733649 CA333409000 |
125 | V>A | No |
ClinGen TOPMed |
|
|
CA413878398 rs1429776081 |
126 | G>D | No |
ClinGen TOPMed |
|
|
rs757375834 CA10482130 |
131 | I>M | No |
ClinGen ExAC gnomAD |
|
|
CA413878446 rs1166253084 |
133 | R>K | No |
ClinGen gnomAD |
|
|
rs1354325399 CA413878455 |
134 | V>A | No |
ClinGen gnomAD |
|
|
rs745999698 CA10482132 |
137 | L>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1304234866 CA413878507 |
141 | K>N | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 144 | G>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA413878528 rs1373547947 |
145 | Q>K | No |
ClinGen gnomAD |
|
|
rs142271331 CA10482135 RCV000901862 |
153 | V>A | No |
ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
rs1163731893 CA413878592 |
154 | H>Y | No |
ClinGen gnomAD |
|
|
CA10482137 rs773092644 |
157 | E>K | No |
ClinGen ExAC gnomAD |
|
|
rs1212589230 CA413878620 |
158 | T>A | No |
ClinGen gnomAD |
|
|
rs746952336 CA10482138 |
159 | S>A | No |
ClinGen ExAC gnomAD |
|
|
rs1316445875 CA413878634 |
160 | D>G | No |
ClinGen TOPMed |
|
|
CA413878635 rs1316445875 |
160 | D>V | No |
ClinGen TOPMed |
|
|
CA333409010 rs774739815 |
161 | S>T | No |
ClinGen TOPMed |
|
|
rs1603031395 CA413878674 |
166 | T>S | No |
ClinGen Ensembl |
|
|
rs770370082 CA10482139 |
166 | T>S | No |
ClinGen ExAC gnomAD |
|
|
CA333409013 rs934131433 |
169 | R>G | No |
ClinGen TOPMed |
|
|
rs148686737 CA10482140 |
170 | N>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 171 | R>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA10482141 rs759114712 |
174 | Q>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA10482142 rs764913469 |
177 | P>L | No |
ClinGen ExAC gnomAD |
|
|
CA413878754 rs1348705148 |
178 | E>K | No |
ClinGen gnomAD |
|
|
CA333409020 rs900747612 |
181 | L>* | No |
ClinGen gnomAD |
|
|
rs900747612 CA413878778 |
181 | L>S | No |
ClinGen gnomAD |
|
|
CA413878814 rs1432927475 COSM1464657 |
186 | S>R | large_intestine [Cosmic] | No |
ClinGen cosmic curated gnomAD |
|
rs866332926 CA333409025 |
194 | N>S | No |
ClinGen Ensembl |
|
|
CA413878877 rs1168156657 |
195 | E>A | No |
ClinGen TOPMed |
|
| TCGA novel | 199 | G>E | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1603031483 CA413878919 |
201 | I>N | No |
ClinGen Ensembl |
|
| TCGA novel | 206 | K>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1273679011 CA413878963 |
207 | Q>* | No |
ClinGen gnomAD |
|
|
CA413878970 rs1184958100 |
208 | P>T | No |
ClinGen TOPMed |
|
|
CA413878980 rs1469440817 |
209 | E>V | No |
ClinGen gnomAD |
|
|
rs757810847 CA10482146 |
212 | N>D | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA10482147 rs757821858 |
213 | F>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs768200842 CA10482148 |
214 | S>N | No |
ClinGen ExAC gnomAD |
|
|
CA10482164 rs774847325 |
221 | L>F | No |
ClinGen ExAC gnomAD |
|
|
CA413879572 rs1257636188 |
228 | W>R | No |
ClinGen TOPMed |
|
|
rs151247663 CA10482167 |
229 | T>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 232 | R>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA413879637 rs1158137958 |
233 | N>H | No |
ClinGen TOPMed gnomAD |
|
|
rs139827001 CA333410318 |
233 | N>S | No |
ClinGen ESP TOPMed |
|
| TCGA novel | 234 | F>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 235 | P>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 235 | P>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1603036701 CA413879676 |
235 | P>T | No |
ClinGen Ensembl |
|
| TCGA novel | 247 | L>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
COSM1112545 CA333410325 rs975208319 |
248 | R>* | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA TOPMed gnomAD |
|
CA413879867 rs1413989206 |
248 | R>Q | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA333410327 rs866036200 |
253 | P>H | No |
ClinGen Ensembl |
|
|
rs896739956 CA333410329 |
257 | M>V | No |
ClinGen Ensembl |
|
|
rs754033371 CA10482171 |
259 | E>G | No |
ClinGen ExAC gnomAD |
|
|
CA413880082 rs1439938887 |
262 | Q>* | No |
ClinGen TOPMed gnomAD |
|
|
rs1439938887 CA413880080 |
262 | Q>K | No |
ClinGen TOPMed gnomAD |
|
|
CA10482184 rs772593826 |
266 | E>K | No |
ClinGen ExAC gnomAD |
|
|
CA413880178 rs772593826 |
266 | E>Q | No |
ClinGen ExAC gnomAD |
|
|
rs1328136951 CA413880210 |
270 | S>I | No |
ClinGen gnomAD |
|
| TCGA novel | 274 | V>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA333410664 rs368227453 |
275 | S>L | No |
ClinGen ESP TOPMed |
|
| TCGA novel | 276 | V>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA413880275 rs1250154668 |
280 | N>H | No |
ClinGen TOPMed |
|
| TCGA novel | 282 | L>missing | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1355006563 CA413880293 |
283 | C>R | No |
ClinGen gnomAD |
|
|
CA10482185 rs773699747 |
284 | P>S | No |
ClinGen ExAC gnomAD |
|
|
CA10482186 rs747290932 |
289 | S>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ExAC NCI-TCGA gnomAD |
|
rs766967950 CA10482187 |
291 | R>Q | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA333410668 rs866642080 COSM1112549 |
291 | R>W | Variant assessed as Somatic; 0.0 impact. large_intestine endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA gnomAD |
|
CA413880356 rs1195556996 |
292 | V>I | No |
ClinGen gnomAD |
|
| TCGA novel | 293 | G>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA333410674 rs903045587 |
301 | Y>C | No |
ClinGen TOPMed |
|
| TCGA novel | 302 | S>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA10482190 rs765424032 |
304 | K>E | No |
ClinGen ExAC gnomAD |
|
|
rs1211972970 CA413880435 |
304 | K>R | No |
ClinGen gnomAD |
|
|
rs1454721453 CA413880493 |
312 | Q>* | No |
ClinGen gnomAD |
|
|
CA10482192 rs757007958 |
316 | V>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs780973470 CA10482193 |
325 | T>A | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
| TCGA novel | 325 | T>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs750320331 CA10482194 |
326 | M>T | No |
ClinGen ExAC gnomAD |
|
|
COSM1643912 CA413880583 rs1167086272 |
326 | M>V | stomach [Cosmic] | No |
ClinGen cosmic curated gnomAD |
|
rs771312533 CA10482204 |
333 | R>* | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
rs768026639 CA10482205 |
333 | R>Q | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs1259974271 CA413879090 |
335 | P>L | No |
ClinGen gnomAD |
|
| TCGA novel | 340 | I>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA10482208 rs775626783 |
342 | I>V | No |
ClinGen ExAC gnomAD |
|
|
CA413879138 rs1373438640 |
343 | P>T | No |
ClinGen gnomAD |
|
|
CA413879159 rs1160561707 |
345 | K>N | No |
ClinGen TOPMed |
|
|
CA10482210 COSM3694263 rs764438772 |
351 | W>C | large_intestine [Cosmic] | No |
ClinGen cosmic curated ExAC gnomAD |
| TCGA novel | 353 | L>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA413879221 rs1440323427 |
354 | P>L | No |
ClinGen TOPMed |
|
|
CA413879252 rs1461549702 |
359 | R>* | No |
ClinGen TOPMed gnomAD |
|
|
CA10482211 rs746611349 |
359 | R>Q | No |
ClinGen ExAC gnomAD |
|
|
CA413879296 rs1171726861 |
364 | S>P | No |
ClinGen TOPMed |
|
|
CA10482224 rs776966238 |
367 | D>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1489168647 CA413879321 |
368 | D>N | No |
ClinGen gnomAD |
|
|
rs746381872 CA10482225 |
369 | M>T | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 372 | N>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs769809960 CA10482226 |
377 | V>I | No |
ClinGen ExAC TOPMed |
|
| TCGA novel | 379 | G>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1256787638 CA413879457 |
380 | L>P | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 383 | F>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
COSM302020 rs570540571 CA10482228 |
389 | R>Q | Variant assessed as Somatic; 0.0 impact. large_intestine central_nervous_system [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA gnomAD |
|
rs1216884286 CA413879555 |
389 | R>W | No |
ClinGen TOPMed |
|
| TCGA novel | 391 | K>Q | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1296994994 CA413879675 |
396 | R>C | No |
ClinGen gnomAD |
|
|
rs1296994994 CA413879674 |
396 | R>G | No |
ClinGen gnomAD |
|
|
CA333411846 rs1049736992 |
396 | R>H | No |
ClinGen TOPMed gnomAD |
|
|
rs1396371882 CA413879697 |
398 | D>H | No |
ClinGen gnomAD |
|
|
CA413879795 rs749313972 |
405 | I>F | No |
ClinGen ExAC gnomAD |
|
|
CA10482245 rs749313972 |
405 | I>V | No |
ClinGen ExAC gnomAD |
|
|
rs1474689821 CA413879835 |
408 | A>T | No |
ClinGen TOPMed |
|
|
CA10482246 rs768810037 |
408 | A>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs774367478 CA10482247 |
409 | D>N | No |
ClinGen ExAC gnomAD |
|
|
rs1312587366 CA413879855 |
410 | G>S | No |
ClinGen gnomAD |
|
|
CA333411851 rs147686087 |
420 | L>P | No |
ClinGen ESP gnomAD |
|
| TCGA novel | 421 | F>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA413880040 rs1480260983 |
425 | Q>* | No |
ClinGen gnomAD |
|
|
CA413880074 rs1239473371 |
427 | E>D | No |
ClinGen gnomAD |
|
|
CA413880134 rs1192645136 |
433 | Y>C | No |
ClinGen gnomAD |
|
|
CA10482251 COSM1464663 rs759470874 |
434 | P>L | large_intestine [Cosmic] | No |
ClinGen cosmic curated ExAC gnomAD |
|
CA10482258 CA413880608 rs780859177 |
435 | M>I | No |
ClinGen ExAC gnomAD |
|
|
rs1008261733 CA333411855 |
435 | M>V | No |
ClinGen TOPMed |
|
|
rs771267893 CA333412332 |
451 | Q>K | No |
ClinGen 1000Genomes |
|
| TCGA novel | 453 | P>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs150241144 CA333412337 |
458 | L>H | No |
ClinGen ESP |
|
|
CA413880784 rs1339817943 |
461 | T>K | No |
ClinGen TOPMed |
|
|
CA10482262 rs749829513 |
464 | S>N | No |
ClinGen ExAC gnomAD |
|
|
rs373154363 CA10482263 |
465 | G>* | No |
ClinGen ESP ExAC gnomAD |
|
| TCGA novel | 465 | G>E | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1196268633 CA413882074 |
476 | Y>C | No |
ClinGen gnomAD |
|
|
COSM25486 CA10482281 rs755480947 |
477 | T>M | Variant assessed as Somatic; 0.0 impact. endometrium breast [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA |
|
rs369412417 CA333412485 |
478 | Y>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs369412417 CA413882105 |
478 | Y>S | No |
ClinGen gnomAD |
|
|
rs1398975091 CA413882130 |
480 | A>T | No |
ClinGen gnomAD |
|
|
CA10482285 rs758566020 |
481 | K>T | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 484 | N>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA413882220 rs1420133704 |
486 | I>V | No |
ClinGen TOPMed gnomAD |
|
|
rs747264055 CA10482287 |
487 | Q>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA10482289 rs202230345 |
496 | G>R | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD |
|
CA413882364 rs1283178322 |
500 | N>S | No |
ClinGen gnomAD |
|
|
rs749074460 CA10482290 |
501 | M>T | No |
ClinGen ExAC gnomAD |
|
|
CA413882398 rs1384610432 |
505 | G>A | No |
ClinGen gnomAD |
|
|
rs1239685787 CA413882485 |
518 | K>T | No |
ClinGen gnomAD |
|
|
rs774209799 CA10482292 |
520 | S>G | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 520 | S>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA413882527 rs1380728742 |
524 | K>E | No |
ClinGen gnomAD |
|
|
rs1234528810 CA413882640 |
525 | V>A | No |
ClinGen gnomAD |
|
|
CA10482310 rs774308946 |
527 | S>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA413882692 rs1214332024 |
529 | L>S | No |
ClinGen gnomAD |
|
|
rs1281951595 CA413882739 |
532 | I>M | No |
ClinGen gnomAD |
|
|
CA10482312 rs772048182 |
532 | I>T | No |
ClinGen ExAC gnomAD |
|
|
CA333412725 rs1021729178 |
532 | I>V | No |
ClinGen TOPMed |
|
|
rs772680443 CA413882755 |
533 | S>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA10482314 rs760246775 |
539 | I>T | No |
ClinGen ExAC gnomAD |
|
|
CA333412731 rs865959217 |
541 | D>E | No |
ClinGen Ensembl |
|
|
CA413882890 rs1252390916 |
541 | D>N | No |
ClinGen gnomAD |
|
|
CA10482315 rs766003380 |
543 | Q>* | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 551 | A>G | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA413883033 rs1201178458 |
552 | I>V | No |
ClinGen gnomAD |
|
|
CA413883058 rs1248371100 |
555 | I>R | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs759877652 CA10482317 |
558 | A>V | No |
ClinGen ExAC gnomAD |
|
|
CA333412736 rs143793727 |
560 | K>E | No |
ClinGen ESP gnomAD |
|
|
CA10482318 rs777544059 |
561 | Y>D | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA413883165 rs1296540761 |
571 | A>P | No |
ClinGen TOPMed |
|
|
CA10482322 rs751682107 |
571 | A>V | No |
ClinGen ExAC gnomAD |
|
|
CA333412747 rs199703952 |
573 | A>V | No |
ClinGen Ensembl |
|
|
CA333412749 rs749257018 |
574 | S>L | No |
ClinGen Ensembl |
|
|
rs1224511266 CA413883209 |
578 | R>Q | No |
ClinGen gnomAD |
|
|
CA413883206 rs1325170958 |
578 | R>W | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs148169764 CA10482352 |
584 | S>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA413883263 rs1376522964 |
585 | T>A | No |
ClinGen gnomAD |
|
|
CA10482356 rs745421533 |
589 | A>V | No |
ClinGen ExAC gnomAD |
|
|
CA413883293 rs1340641709 |
590 | R>G | No |
ClinGen TOPMed |
|
|
CA10482357 rs769323802 |
591 | V>I | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 592 | E>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
VAR_028816 rs5962707 CA10482358 |
593 | I>M | No |
ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
CA333412886 rs867127195 |
593 | I>V | No |
ClinGen Ensembl |
|
|
CA333412890 rs1039038876 |
597 | N>S | No |
ClinGen TOPMed gnomAD |
|
|
CA413883363 rs1457081415 COSM1464667 |
600 | R>W | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA TOPMed gnomAD |
|
CA413883371 rs1178680976 |
601 | H>R | No |
ClinGen gnomAD |
|
|
CA413883392 rs1310362627 |
604 | D>H | No |
ClinGen TOPMed |
|
|
rs763348053 CA10482359 |
605 | E>D | No |
ClinGen ExAC gnomAD |
|
|
rs1381658400 CA413883399 |
605 | E>K | No |
ClinGen gnomAD |
|
|
rs765603048 CA333412893 |
606 | P>L | No |
ClinGen Ensembl |
|
|
rs1365373760 CA413883437 |
610 | Q>H | No |
ClinGen TOPMed |
|
|
CA10482360 rs769142651 |
610 | Q>R | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 615 | T>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA413883485 rs1296863647 |
617 | T>I | No |
ClinGen gnomAD |
|
|
rs768111415 CA10482363 |
618 | N>Y | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs750467468 CA10482364 |
620 | S>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA413883546 rs1471635813 |
624 | K>* | No |
ClinGen TOPMed |
|
|
rs1049961194 CA333412901 |
631 | P>L | No |
ClinGen TOPMed gnomAD |
|
|
CA413883720 rs1009095037 |
633 | A>S | No |
ClinGen TOPMed gnomAD |
|
|
rs1009095037 CA333412903 |
633 | A>T | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
rs1235115625 CA413883737 |
635 | P>L | No |
ClinGen gnomAD |
|
|
rs1218789175 CA413884593 |
638 | V>I | No |
ClinGen gnomAD |
|
|
rs1218789175 CA413884597 |
638 | V>L | No |
ClinGen gnomAD |
|
|
CA10482381 rs748615705 |
639 | P>T | No |
ClinGen ExAC gnomAD |
|
|
CA413884687 rs137926336 |
641 | P>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs137926336 CA10482382 |
641 | P>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs773785255 CA10482383 |
642 | G>E | No |
ClinGen ExAC gnomAD |
|
|
rs760605992 CA10482384 |
643 | A>V | No |
ClinGen ExAC gnomAD |
|
|
CA333414041 rs868360080 |
644 | S>Y | No |
ClinGen Ensembl |
|
|
CA413884764 rs1391876184 |
646 | Q>K | No |
ClinGen TOPMed |
|
|
rs375574266 CA333414045 |
647 | T>A | No |
ClinGen ESP TOPMed gnomAD |
|
|
rs142495888 CA10482386 |
649 | G>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA10482387 COSM301171 rs759731966 |
652 | P>L | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA |
|
CA413884981 rs1415929783 |
653 | G>V | No |
ClinGen gnomAD |
|
|
rs757129526 CA10482390 |
655 | P>L | No |
ClinGen ExAC |
|
|
rs1424254872 CA413885051 |
656 | S>G | No |
ClinGen gnomAD |
|
|
rs1161808565 CA413885139 |
659 | N>S | No |
ClinGen gnomAD |
|
|
rs767297602 CA10482391 |
660 | R>C | No |
ClinGen ExAC gnomAD |
|
|
rs765429808 CA10482405 |
661 | R>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA10482406 rs150560497 |
661 | R>Q | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA413887021 rs1357231261 |
667 | N>D | No |
ClinGen gnomAD |
|
|
CA413887053 rs1446753780 |
669 | Q>R | No |
ClinGen gnomAD |
|
|
rs1262535557 CA413887071 |
670 | G>E | No |
ClinGen TOPMed |
|
|
rs1303063712 CA413887098 |
672 | A>T | No |
ClinGen gnomAD |
|
| TCGA novel | 674 | K>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs761443853 CA10482407 |
675 | T>A | No |
ClinGen ExAC gnomAD |
|
|
rs1242980968 CA413887172 |
676 | I>T | No |
ClinGen gnomAD |
|
|
rs767372773 CA10482408 |
676 | I>V | Variant assessed as Somatic; 0.0003762 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA413887187 rs1276876566 |
677 | S>N | No |
ClinGen gnomAD |
|
|
CA413887214 rs1442211915 |
678 | D>E | No |
ClinGen gnomAD |
|
| TCGA novel | 678 | D>G | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA413887255 rs1325556777 |
680 | W>* | No |
ClinGen TOPMed |
|
|
CA333416023 rs1000366615 |
681 | E>K | No |
ClinGen Ensembl |
|
|
rs182010941 CA10482409 |
682 | S>N | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs1033181298 CA413887384 CA333416029 COSM1112576 |
687 | E>D | Variant assessed as Somatic; impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA TOPMed gnomAD |
|
rs766494208 CA10482411 |
687 | E>V | No |
ClinGen ExAC gnomAD |
|
|
rs753387931 CA10482412 |
688 | K>R | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 691 | G>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 691 | G>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs778643864 CA10482414 |
693 | I>M | No |
ClinGen ExAC gnomAD |
|
|
rs1160233770 CA413887499 |
693 | I>T | No |
ClinGen gnomAD |
|
|
CA413887505 rs1359519271 |
694 | D>N | No |
ClinGen TOPMed |
|
|
rs1413691167 CA413887515 |
695 | H>Y | No |
ClinGen TOPMed gnomAD |
|
|
rs566763673 CA333416035 |
697 | H>R | No |
ClinGen TOPMed |
|
| TCGA novel | 697 | H>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs752426407 CA10482415 |
698 | Y>C | No |
ClinGen ExAC gnomAD |
|
|
CA413887552 rs1404746663 |
700 | R>C | No |
ClinGen TOPMed |
|
|
COSM1169177 CA10482416 rs139595497 |
700 | R>H | pancreas [Cosmic] | No |
ClinGen cosmic curated ESP ExAC TOPMed gnomAD |
|
CA10482419 rs747373668 |
702 | Y>H | No |
ClinGen ExAC gnomAD |
|
|
CA10482418 rs747373668 |
702 | Y>N | No |
ClinGen ExAC gnomAD |
|
|
rs144581178 CA10482421 |
703 | P>H | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs144581178 CA10482420 |
703 | P>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 704 | E>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs769865919 CA10482422 |
706 | I>L | No |
ClinGen ExAC gnomAD |
|
|
rs763255993 COSM3843120 CA10482424 |
708 | R>Q | Variant assessed as Somatic; 0.0 impact. breast [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA gnomAD |
|
CA10482423 rs775530156 COSM1661343 |
708 | R>W | kidney Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated ExAC NCI-TCGA gnomAD |
|
CA10482425 rs139787193 |
709 | K>E | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 712 | F>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs773059352 CA10482426 |
715 | R>S | No |
ClinGen ExAC gnomAD |
|
|
rs145336776 CA10482427 |
719 | S>G | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA10482428 rs766364629 |
722 | Y>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs969939256 CA333416053 |
722 | Y>H | No |
ClinGen TOPMed |
|
|
CA333416056 rs1027038132 |
727 | A>S | No |
ClinGen Ensembl |
|
|
rs147676341 CA10482429 |
727 | A>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 728 | K>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1196926191 CA413887759 |
730 | V>A | No |
ClinGen TOPMed gnomAD |
|
|
CA10482431 rs764825632 |
734 | G>* | No |
ClinGen ExAC gnomAD |
|
|
CA413887784 rs1177634348 |
734 | G>A | No |
ClinGen gnomAD |
|
| TCGA novel | 738 | K>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs952432802 CA333416065 |
740 | D>Y | No |
ClinGen Ensembl |
|
|
CA333416068 rs980017985 |
741 | D>E | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 741 | D>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 743 | K>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1256515568 CA413887850 |
744 | S>C | No |
ClinGen TOPMed |
|
|
CA10482435 rs751905627 |
745 | A>D | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA333416073 rs751905627 |
745 | A>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA10482434 rs777354939 |
745 | A>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA333416075 rs369836821 |
746 | R>* | No |
ClinGen ESP TOPMed |
|
|
CA10482436 COSM1112586 rs757628984 |
746 | R>Q | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
rs781610685 CA10482437 |
751 | F>C | No |
ClinGen ExAC gnomAD |
|
|
CA10482438 rs373355432 |
755 | I>M | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA333417060 rs866793735 |
760 | H>N | No |
ClinGen Ensembl |
|
|
CA10482453 rs201227251 |
760 | H>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs763743766 CA10482454 |
761 | E>A | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 763 | A>E | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA413888493 rs751214007 |
765 | D>N | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA10482455 rs751214007 |
765 | D>Y | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA10482458 rs767889232 |
770 | P>L | No |
ClinGen ExAC |
|
|
rs750833100 CA10482459 |
771 | M>V | No |
ClinGen ExAC gnomAD |
|
|
rs756643724 CA10482460 |
773 | C>F | No |
ClinGen ExAC gnomAD |
|
|
rs1342566837 CA413888610 |
774 | P>T | No |
ClinGen gnomAD |
|
|
rs749335623 CA10482462 |
777 | I>T | No |
ClinGen ExAC gnomAD |
|
|
CA10482461 rs201720137 |
777 | I>V | No |
ClinGen ExAC gnomAD |
|
|
rs1357148175 CA413888672 |
778 | R>* | No |
ClinGen gnomAD |
|
|
rs755021752 CA10482463 |
778 | R>Q | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA413888829 rs1448318633 |
789 | M>T | No |
ClinGen gnomAD |
|
|
CA10482465 rs748404348 |
789 | M>V | No |
ClinGen ExAC gnomAD |
|
|
rs1184976978 CA413888880 |
791 | Y>* | No |
ClinGen gnomAD |
|
|
CA333417081 rs373429502 |
794 | A>V | No |
ClinGen ESP gnomAD |
|
| TCGA novel | 795 | Y>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs200280161 CA10482467 |
798 | D>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA10482466 rs200280161 |
798 | D>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA413889045 rs1316743747 |
798 | D>Y | No |
ClinGen gnomAD |
|
|
rs1280451655 CA413889102 |
800 | T>I | No |
ClinGen TOPMed |
|
|
rs1413350929 CA413889124 |
801 | G>V | No |
ClinGen TOPMed |
|
|
CA10482468 rs377553613 |
803 | D>N | No |
ClinGen ESP ExAC gnomAD |
|
|
CA10482469 rs146117325 |
803 | D>V | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs1419661345 CA413889188 |
804 | R>* | No |
ClinGen gnomAD |
|
|
CA10482470 rs151274803 |
804 | R>Q | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs761429928 CA10482474 COSM1112590 |
810 | A>V | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA gnomAD |
|
CA413889352 rs1307225446 |
811 | V>A | No |
ClinGen TOPMed gnomAD |
|
|
CA413889359 rs1351358970 |
812 | A>T | No |
ClinGen gnomAD |
|
|
rs775455585 CA10482497 |
814 | D>N | No |
ClinGen ExAC gnomAD |
|
|
rs749201135 CA10482498 |
815 | I>V | No |
ClinGen ExAC gnomAD |
|
|
rs768685513 CA10482499 |
820 | T>A | No |
ClinGen ExAC gnomAD |
|
|
CA413889572 rs1230756093 |
824 | R>G | No |
ClinGen gnomAD |
|
|
rs759930057 CA333418477 |
825 | V>M | No |
ClinGen gnomAD |
|
|
rs199864873 CA10482500 |
828 | V>I | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA10482501 rs184295976 |
829 | G>S | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA10482502 rs188839866 |
833 | I>M | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs772860329 CA10482503 |
834 | C>S | No |
ClinGen ExAC gnomAD |
|
|
rs1233150837 CA413889659 |
837 | G>S | No |
ClinGen TOPMed |
|
| TCGA novel | 838 | N>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1431986748 CA413889674 |
839 | N>D | No |
ClinGen TOPMed gnomAD |
|
|
CA10482504 rs760344396 |
844 | Y>C | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs766677315 CA10482505 |
846 | H>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA10482506 rs754278508 |
850 | S>N | No |
ClinGen ExAC gnomAD |
|
|
rs759931639 COSM1112596 CA10482507 |
852 | E>D | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA gnomAD |
|
rs1466189752 CA413889786 |
854 | T>I | No |
ClinGen gnomAD |
No associated diseases with Q6NSI4
No regional properties for Q6NSI4
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q6NSI4 | |||
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| nuclear speck | A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy. |
| replication fork | The Y-shaped region of a replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| RNA binding | Binding to an RNA molecule or a portion thereof. |
| single-stranded DNA binding | Binding to single-stranded DNA. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| negative regulation of double-strand break repair via homologous recombination | Any process that stops, prevents, or reduces the frequency, rate or extent of double-strand break repair via homologous recombination. |
| regulation of DNA repair | Any process that modulates the frequency, rate or extent of DNA repair. |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSGESGQPEA | GPSHAGLDWP | NPERNRAGVP | GGVIRRAGSQ | GPRSWIQKVL | EQIMDSPRQC |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VTPSEVVPVT | VLAVQRYLLE | DEPRDTVPKP | PLYCYDVTIS | DGVYQEKCYL | DPSLNSLVYQ |
| 130 | 140 | 150 | 160 | 170 | 180 |
| NILKVGIQMR | ISRVSCLYNE | KRIGQGILCI | DNVHCGETSD | SISLETPFRN | RAHQEKPERP |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LRGGKSHYLA | LWNNEDPYGD | IWLTDKQPEE | HNFSDTKIIS | LSHLEMTWTN | RRNFPALLVR |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ILHKSKLRYY | GKPDKKMIEP | YQTFLEVADS | SGTVSVIMWN | ALCPEWYKSL | RVGLVLLLQD |
| 310 | 320 | 330 | 340 | 350 | 360 |
| YSVKKSYPFR | IQPVPVDPQI | KLISTMEICL | NLRDPPTNII | IIPEKQVKPE | WRLPKLNHRF |
| 370 | 380 | 390 | 400 | 410 | 420 |
| TTRSELDDMP | ENCICDVIGL | LVFVGRVQRS | KKKENREDFW | SYRWIHIADG | TSEQPFIVEL |
| 430 | 440 | 450 | 460 | 470 | 480 |
| FSTSQPEIFE | NIYPMAYFVC | TQLKVVRNDN | QVPKLLYLTT | TNESGVFITG | HRGQPYTYDA |
| 490 | 500 | 510 | 520 | 530 | 540 |
| KVKNFIQWIR | TKSDSGEQKN | MVIGGYYPYP | PVPETFSKYS | SSIKVESLLT | AISEVRKEIE |
| 550 | 560 | 570 | 580 | 590 | 600 |
| DLQYREQKRI | AIQGIITAIK | YIPHSSATES | ASASETLRNA | NRPSTSQAAR | VEIQERNGKR |
| 610 | 620 | 630 | 640 | 650 | 660 |
| HQDDEPVNSQ | YFQTTSTNLS | LSNKIRILQG | PHANPVAVPQ | PGASVQTKGI | KPGMPSIFNR |
| 670 | 680 | 690 | 700 | 710 | 720 |
| RANINANLQG | KARKTISDRW | ESQLWREKKF | GLIDHLHYSR | VYPESIPRKF | MFEHRKFLSD |
| 730 | 740 | 750 | 760 | 770 | 780 |
| QYNSQPAKYV | PPEGRPPKLD | DFKSARSLGH | FEVTILGLNH | EIAIDVAFLP | MYCPEDIRTS |
| 790 | 800 | 810 | 820 | 830 | 840 |
| QIDTLLTSMN | YSCAYPQDTT | GNDRLPGPRA | VAGDIIKAAT | ELDRVHIVGI | LDICNLGNNK |
| 850 | |||||
| VEVYLHKIYS | PENTS |