B2GV47

PR
Gene name
Radx
Protein name
RPA-related protein RADX
Names
Species
Rattus norvegicus (Rat)
KEGG Pathway
rno:680663
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-59 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B2GV47

Entry ID Method Resolution Chain Position Source
AF-B2GV47-F1 Predicted AlphaFoldDB

No variants for B2GV47

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B2GV47

No associated diseases with B2GV47

No regional properties for B2GV47

Type Name Position InterPro Accession
No domain, repeats, and functional sites for B2GV47

Functions

Description
EC Number
Subcellular Localization
  • Chromosome
  • Recruited to replication forks
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
nuclear speck A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.
replication fork The Y-shaped region of a replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes.

1 GO annotations of molecular function

Name Definition
single-stranded DNA binding Binding to single-stranded DNA.

2 GO annotations of biological process

Name Definition
negative regulation of double-strand break repair via homologous recombination Any process that stops, prevents, or reduces the frequency, rate or extent of double-strand break repair via homologous recombination.
regulation of DNA repair Any process that modulates the frequency, rate or extent of DNA repair.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q6NSI4 RADX RPA-related protein RADX Homo sapiens (Human) PR
Q8C779 Radx RPA-related protein RADX Mus musculus (Mouse) PR
10 20 30 40 50 60
MSGESDQPQP GPSHAGLYLE HRERDQAGVP GGVIRRAGSQ RHRSWIQTVI EQITGSPRQC
70 80 90 100 110 120
VTLSEVVPVS VLAVQRYLLE DEPRDTVPKP PLYCYDVTIS DGVYQEKCYL DPSLNFLVYQ
130 140 150 160 170 180
NILKVGIEMR ISRVSCLYNE KRLGQGILCI DKVHCGEPLD VISVETPFRN RAHEEKPERP
190 200 210 220 230 240
LRGSKSHYLA LWNNEDPYGD IWKTNKQPEE FNFNNTKIIS LSHLEMTWHN RKNFPALLVR
250 260 270 280 290 300
ILHKSKLRYY GKPNKKMIEP YQTYLEVADS SGMVSVIMWN ALCPEWYKSL RVGLILLLQD
310 320 330 340 350 360
YSVKKSYPLR IQPDPVDPQM KLISTMEICL NLRDPPTNIV IIPEKQLKSE WKLPKLINRF
370 380 390 400 410 420
ITRSELDDMP ENSICDVIGM LSFVGRVQRS KKKENSEDFW SYRWIHITDG TSEQPFIVQL
430 440 450 460 470 480
FSTSQPEVFE NIYPMTYFVC TQLKVVRNNS QVPKLLYLTT TNESRVLITG HRGQPYTYDT
490 500 510 520 530 540
KAKKIIQWIK TKTNLEAKNT VIGGYYPYPP VPETFSKYSR FIKAESLLTT ISEVRKVIED
550 560 570 580 590 600
LQYREQKRIA IQGIITAIKY IPYNHSAKSA PASETLQNAS PPSTSQAAAK EGHYHERGSK
610 620 630 640 650 660
RSQDDRPMDS LPMVLSLCAK RKILQGPTAN PVPVPQPHSS AQMKGNKPNI PSRENSTANA
670 680 690 700 710 720
TGKSKRIIND RWESQLWRDK KFSLRDHLHY GHVDPESIPR KFILGHEKFL TQQFNSQPAK
730 740 750 760 770 780
YVPPEGKPPK LDEFQSARSL GHFEVTILGL NHEIAIDVAF LPMYSPEDVE TSQIDTFLTC
790 800 810 820 830 840
MNYSCVYPPA APVSGRVPDP KAVAGDIVKA AADLDRVHII GILDICNLGN NKVEVCLQKI
YTPE