Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q6NKX3

Entry ID Method Resolution Chain Position Source
AF-Q6NKX3-F1 Predicted AlphaFoldDB

83 variants for Q6NKX3

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH05244977 4 K>N No 1000Genomes
ENSVATH01639643 5 F>L No 1000Genomes
ENSVATH11001052 7 T>I No 1000Genomes
ENSVATH05244973 7 T>S No 1000Genomes
ENSVATH00205814 9 S>A No 1000Genomes
ENSVATH11001050 16 S>I No 1000Genomes
ENSVATH01639631 21 A>V No 1000Genomes
ENSVATH01639628 25 Q>H No 1000Genomes
ENSVATH01639629 25 Q>L No 1000Genomes
tmp_2_1448490_G_A 30 L>F No 1000Genomes
ENSVATH11001049 34 N>I No 1000Genomes
tmp_2_1448474_G_A 35 A>V No 1000Genomes
tmp_2_1448460_C_T 40 V>I No 1000Genomes
ENSVATH01639626 43 K>R No 1000Genomes
ENSVATH05244971 51 M>T No 1000Genomes
ENSVATH05244970 52 L>F No 1000Genomes
ENSVATH01639625 64 V>L No 1000Genomes
ENSVATH01639624 73 T>S No 1000Genomes
ENSVATH01639623 74 M>V No 1000Genomes
tmp_2_1448346_T_A 78 N>Y No 1000Genomes
ENSVATH01639622 82 T>S No 1000Genomes
ENSVATH13947857 100 G>C No 1000Genomes
ENSVATH05244969 101 R>T No 1000Genomes
ENSVATH00205813 104 C>F No 1000Genomes
ENSVATH00205813 104 C>S No 1000Genomes
tmp_2_1448258_A_G 107 V>A No 1000Genomes
ENSVATH13947856 108 G>E No 1000Genomes
ENSVATH05244968 112 A>V No 1000Genomes
ENSVATH00205812 115 F>C No 1000Genomes
ENSVATH05244967 116 A>S No 1000Genomes
ENSVATH13947784 118 G>D No 1000Genomes
ENSVATH05244966 124 L>V No 1000Genomes
ENSVATH00205811 131 D>E No 1000Genomes
ENSVATH05244965 133 T>I No 1000Genomes
ENSVATH11001046 145 D>V No 1000Genomes
tmp_2_1448114_G_A 155 A>V No 1000Genomes
ENSVATH01639617 180 K>Q No 1000Genomes
tmp_2_1448037_C_T 181 D>N No 1000Genomes
tmp_2_1448021_C_A 186 C>F No 1000Genomes
tmp_2_1448012_A_T 189 L>* No 1000Genomes
tmp_2_1447979_A_G 200 V>A No 1000Genomes
tmp_2_1447962_C_G 206 A>P No 1000Genomes
ENSVATH01639615 207 D>N No 1000Genomes
tmp_2_1447952_G_A 209 A>V No 1000Genomes
ENSVATH00205808 214 A>T No 1000Genomes
tmp_2_1447935_A_T 215 S>T No 1000Genomes
ENSVATH11000854 227 R>K No 1000Genomes
tmp_2_1447886_C_A 231 G>V No 1000Genomes
ENSVATH11000853 238 V>A No 1000Genomes
ENSVATH01639614 243 G>A No 1000Genomes
ENSVATH01639613 247 L>F No 1000Genomes
tmp_2_1447816_A_C 254 D>E No 1000Genomes
ENSVATH05244964 256 E>D No 1000Genomes
ENSVATH00205806 267 E>V No 1000Genomes
tmp_2_1447762_A_C 272 S>R No 1000Genomes
ENSVATH01639612 283 L>M No 1000Genomes
ENSVATH00205805 286 L>V No 1000Genomes
tmp_2_1447718_G_A 287 T>I No 1000Genomes
ENSVATH01639609 303 V>F No 1000Genomes
ENSVATH05244956 304 P>S No 1000Genomes
ENSVATH05244956 304 P>T No 1000Genomes
tmp_2_1447540_T_G 307 K>Q No 1000Genomes
ENSVATH01639607 313 G>V No 1000Genomes
ENSVATH11000850 316 E>* No 1000Genomes
ENSVATH00205804 320 H>Y No 1000Genomes
tmp_2_1447440_A_G 340 I>T No 1000Genomes
ENSVATH01639604 341 L>I No 1000Genomes
ENSVATH05244955 343 L>V No 1000Genomes
ENSVATH11000845 355 P>L No 1000Genomes
ENSVATH13947783 358 R>Q No 1000Genomes
ENSVATH05244946 366 A>G No 1000Genomes
ENSVATH01639602 378 L>V No 1000Genomes
tmp_2_1447152_G_A 407 T>I No 1000Genomes
ENSVATH05244945 412 R>L No 1000Genomes
ENSVATH05244942 414 G>E No 1000Genomes
ENSVATH11000674 414 G>R No 1000Genomes
ENSVATH05244941 420 D>E No 1000Genomes
ENSVATH05244940 422 E>K No 1000Genomes
ENSVATH11000673 427 M>I No 1000Genomes
ENSVATH05244939 431 L>* No 1000Genomes
ENSVATH01639598 433 I>N No 1000Genomes
ENSVATH05244938 436 W>C No 1000Genomes
ENSVATH05244936 442 H>Y No 1000Genomes

No associated diseases with Q6NKX3

3 regional properties for Q6NKX3

Type Name Position InterPro Accession
domain F-box domain 12 - 64 IPR001810
domain FBD domain 363 - 446 IPR006566
repeat Leucine-rich repeat 2 168 - 193 IPR013101

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

23 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q8LF09 At4g00160 F-box/FBD/LRR-repeat protein At4g00160 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SMT9 At3g49020 FBD-associated F-box protein At3g49020 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FF58 At5g60610 FBD-associated F-box protein At5g60610 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FJV2 At5g56560 Putative FBD-associated F-box protein At5g56560 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LJF9 At3g26920 F-box/FBD/LRR-repeat protein At3g26920 Arabidopsis thaliana (Mouse-ear cress) PR
Q3EAE5 At4g00315 Putative F-box/FBD/LRR-repeat protein At4g00315 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LQM1 At1g32375 Probable FBD-associated F-box protein At1g32375 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FM92 At5g56390 Putative FBD-associated F-box protein At5g56390 Arabidopsis thaliana (Mouse-ear cress) PR
Q9C8Y5 At1g66320 FBD-associated F-box protein At1g66320 Arabidopsis thaliana (Mouse-ear cress) PR
Q9C8Y6 At1g66310 FBD-associated F-box protein At1g66310 Arabidopsis thaliana (Mouse-ear cress) PR
Q9ZV94 At1g78760 Putative F-box/FBD/LRR-repeat protein At1g78760 Arabidopsis thaliana (Mouse-ear cress) PR
Q93ZK9 At5g18770 F-box/FBD/LRR-repeat protein At5g18770 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LZZ2 At3g60710 Putative FBD-associated F-box protein At3g60710 Arabidopsis thaliana (Mouse-ear cress) PR
Q56XS8 At1g13780 F-box/FBD/LRR-repeat protein At1g13780 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FLA3 At5g44940 Putative FBD-associated F-box protein At5g44940 Arabidopsis thaliana (Mouse-ear cress) PR
Q0V7P8 At5g27750 FBD-associated F-box protein At5g27750 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FL99 At5g44980 F-box/FBD/LRR-repeat protein At5g44980 Arabidopsis thaliana (Mouse-ear cress) PR
O80762 At1g60410 FBD-associated F-box protein At1g60410 Arabidopsis thaliana (Mouse-ear cress) PR
Q9M8L5 At1g80470 F-box/FBD/LRR-repeat protein At1g80470 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FJC0 At5g53640 Putative FBD-associated F-box protein At5g53640 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FZ52 At1g16930 F-box/FBD/LRR-repeat protein At1g16930 Arabidopsis thaliana (Mouse-ear cress) PR
Q1PFI4 At1g60400 F-box protein At1g60400 Arabidopsis thaliana (Mouse-ear cress) PR
Q56YH2 At5g18780 FBD-associated F-box protein At5g18780 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MEQKFKTDSM NEDRISDLPD ALLLQILSSL PTENAIATSV LSKRWRSLWT MLPKLKFDSN
70 80 90 100 110 120
FNPVFDDDNI DPTMFSENVY KTLSLHKAPV LESLHLSFEG RTDCLHVGIW IATAFARGVR
130 140 150 160 170 180
KLVLDSFYQE DQTVTLPSVL FSYNDSLEIL KLKCAIDLDF PSRVCLKSLR KLYLDQVHFK
190 200 210 220 230 240
DEESVCNLLC GCPSLQDLVV HRYSNADVAT FTIASPSLQR LTIEDLRQEG GYGNGSYVIN
250 260 270 280 290 300
APGLKYLNIN GVIDIESCLI DKALELEEAK ISNVSGITNE NILESLTSAK RLILHLSPLE
310 320 330 340 350 360
VKVPTGKIFD QLGCLELLTH EREWWNLLSI MLDSSPKLQI LKLTDVYLHD NKTNPDERKW
370 380 390 400 410 420
NPPKCAPECL LFHLETFLWI GYEWQRGDEK EVATYILENA RRLKKATFST KRIGREKLED
430 440
FEKRREMLNE LAIVLWDSNS CHLVFEST