Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q6EPQ3

Entry ID Method Resolution Chain Position Source
AF-Q6EPQ3-F1 Predicted AlphaFoldDB

No variants for Q6EPQ3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6EPQ3

No associated diseases with Q6EPQ3

4 regional properties for Q6EPQ3

Type Name Position InterPro Accession
domain GPCR, family 2, extracellular hormone receptor domain 130 - 222 IPR001879
domain GPCR, family 2-like, transmembrane domain 240 - 502 IPR017981
conserved_site GPCR, family 2, secretin-like, conserved site 147 - 171 IPR017983-1
conserved_site GPCR, family 2, secretin-like, conserved site 490 - 505 IPR017983-2

Functions

Description
EC Number
Subcellular Localization
  • Membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

1 GO annotations of molecular function

Name Definition
transmembrane transporter activity Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

4 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q8BH31 Mfsd8 Major facilitator superfamily domain-containing protein 8 Mus musculus (Mouse) PR
Q8H398 SPX6 SPX domain-containing protein 6 Oryza sativa subsp japonica (Rice) PR
Q0JAW2 Os04g0573000 SPX domain-containing membrane protein Os04g0573000 Oryza sativa subsp japonica (Rice) PR
Q2V4F9 At1g63010 SPX domain-containing membrane protein At1g63010 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MVNFGKRLMA DQLEEWKEYY INYKMMKKKV KQYVQQTQNG GRNREQVLKE FSRMLDDQIE
70 80 90 100 110 120
KIVLFLLQQQ GHLASRIEKL GEERALLMEQ ADASQISELR EAYREVGIDL MKLLRFVDMN
130 140 150 160 170 180
ATGIRKILKK FDKRFGYKFT DYYVSTRANH PCSQLQQIFK QVGIVAVVGA LSRNLAFLQD
190 200 210 220 230 240
HQGNFPSIYD HPSITLKDPI IEQINHSVQK LTHATNLLQF IGQHALIIPE DMHSGSEDLV
250 260 270 280 290 300
DDQSYHFMSL LLNLANTFLY MVNTYIIVPT ADDYSVSLGA AATVCGVIIG SMAVAQVFSS
310 320 330 340 350 360
VYFSAWSNKS YFRPLVFSSI MLFLGNLLYA LAYDVNSLTV LIVGRLLCGL GSARAVNRRY
370 380 390 400 410 420
ISDCVPLKTR LQASAGFVSA SALGMACGPA LAGLLQTNFK IYGFTFDQNT LPGWIMCLAW
430 440 450 460 470 480
ITYLFWLWIS FKEPDHIVRE NSVNTPSSDS GHRRNSNLED GLAQPFLIDA KESLDENGED
490 500 510 520 530 540
NDENEEDPED SHKPATSLAA AYRLLTPSVK VQLLIYFMLK FAMEILLSES SVVTTFYFNW
550 560 570 580 590 600
STSTVAMFLA VLGLTVLPVN VIVGSYVTNL FQDRQILVAS EIMVLIGIAM SFRFTSHYSV
610 620 630 640 650 660
PQYVSSALIT FVFAEVLEGV NLSLLSRVMS SRLSRGTYNG GLLSTEAGTL ARVAADMTIT
670 680 690
AAGYLGQNSL LNVTLLPSFV ICVASIVATF CTYNSLY