Q2V4F9
Gene name |
At1g63010 (F16M19.18, F16P17.18) |
Protein name |
SPX domain-containing membrane protein At1g63010 |
Names |
|
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT1G63010 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q2V4F9
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q2V4F9-F1 | Predicted | AlphaFoldDB |
22 variants for Q2V4F9
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_1_23350773_C_A | 54 | M>I | No | 1000Genomes | |
| tmp_1_23350406_A_T | 99 | L>Q | No | 1000Genomes | |
| tmp_1_23350403_C_T | 100 | R>H | No | 1000Genomes | |
| tmp_1_23350254_G_C | 150 | H>D | No | 1000Genomes | |
| ENSVATH05042762 | 164 | V>L | No | 1000Genomes | |
| tmp_1_23350033_C_T | 193 | V>I | No | 1000Genomes | |
| tmp_1_23349814_G_A | 239 | T>I | No | 1000Genomes | |
| ENSVATH05042752 | 339 | A>V | No | 1000Genomes | |
| tmp_1_23349123_A_T | 440 | D>E | No | 1000Genomes | |
| ENSVATH05042744 | 441 | G>E | No | 1000Genomes | |
| ENSVATH05042743 | 442 | E>A | No | 1000Genomes | |
| ENSVATH00115427 | 444 | N>I | No | 1000Genomes | |
| ENSVATH00115427 | 444 | N>T | No | 1000Genomes | |
| ENSVATH05042742 | 446 | R>P | No | 1000Genomes | |
| ENSVATH13705146 | 450 | T>I | No | 1000Genomes | |
| ENSVATH00115425 | 470 | T>N | No | 1000Genomes | |
| ENSVATH14395663 | 477 | D>N | No | 1000Genomes | |
| tmp_1_23348909_C_T | 482 | D>N | No | 1000Genomes | |
| ENSVATH13705135 | 600 | V>I | No | 1000Genomes | |
| tmp_1_23348317_T_A | 609 | I>L | No | 1000Genomes | |
| ENSVATH05042711 | 613 | A>S | No | 1000Genomes | |
| ENSVATH01446334 | 677 | P>S | No | 1000Genomes |
No associated diseases with Q2V4F9
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| membrane | A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
| plant-type vacuole membrane | The lipid bilayer surrounding a vacuole that retains the same shape regardless of cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this component is found in Arabidopsis thaliana. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| transmembrane transporter activity | Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| transmembrane phosphate ion transport from cytosol to vacuole | The directed movement of phosphate ions from the cytosol across the vacuolar membrane and into the vacuolar lumen. |
4 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q8BH31 | Mfsd8 | Major facilitator superfamily domain-containing protein 8 | Mus musculus (Mouse) | PR |
| Q8H398 | SPX6 | SPX domain-containing protein 6 | Oryza sativa subsp japonica (Rice) | PR |
| Q0JAW2 | Os04g0573000 | SPX domain-containing membrane protein Os04g0573000 | Oryza sativa subsp japonica (Rice) | PR |
| Q6EPQ3 | Os02g0678200 | SPX domain-containing membrane protein Os02g45520 | Oryza sativa subsp japonica (Rice) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MVAFGKYLQR | KQIEEWSGYY | INYKLMKKKV | KQYAEQIQGG | SQHPRHVLKD | FSRMLDTQIE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| TTVLFMLEQQ | GLLSGRLAKL | RESHDAILEQ | PDISRIFELR | EAYRDVGRDL | LQLLKFVELN |
| 130 | 140 | 150 | 160 | 170 | 180 |
| AIGLRKILKK | FDKRFGYRFA | DYYVKTRANH | PYSQLQQVFK | HVGVGAVVGA | ISRNLHELQE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| NEGSFYSIYD | QPVLPAQDPV | VEAINNAVDK | LTFSTNFLNF | LAQHALIMQD | DLVTPSEDTI |
| 250 | 260 | 270 | 280 | 290 | 300 |
| DERSYHFNSL | LLNLGNTFLY | MVNTYIIVPT | ADDYSMSLGA | AATVCGVVIG | SMAVAQVFSS |
| 310 | 320 | 330 | 340 | 350 | 360 |
| VYFSAWSNKS | YFKPLVFSSI | ALFIGNLMYA | LAYDANSIAL | LLLGRVCCGL | GSARAVNRRY |
| 370 | 380 | 390 | 400 | 410 | 420 |
| ISDCVPLRIR | MQASAGFVSA | SALGMACGPA | LAGLLQIKFK | FYKFTFNQST | LPGWVMAVAW |
| 430 | 440 | 450 | 460 | 470 | 480 |
| LFYLVWLCIS | FREPLRDTED | GEKNNRNETT | SDRVESSRVE | EGLRLPLLIT | SGIKPEDEEE |
| 490 | 500 | 510 | 520 | 530 | 540 |
| CDESEESPED | SHKPANSFIE | AYRLLTPSVK | VQLLIYFMLK | YSMEILLSES | SVITSYYFSW |
| 550 | 560 | 570 | 580 | 590 | 600 |
| TTSSVAIFLA | CLGLTVLPIN | ILVGSYISNM | FEDRQILLTS | EIIVFLGILF | SFNLFVPYTV |
| 610 | 620 | 630 | 640 | 650 | 660 |
| PQYVISGLIM | FVAAEVLEGV | NLSLLSRVMS | SRLSKGTYNG | GLLSTEAGTL | ARVVADATIT |
| 670 | 680 | 690 | |||
| LGGYLGRGHL | LNATLLPSLV | ICIGSIVATC | CTYNSLY |