Q6DIQ3
Gene name |
ppp1r7 (sds22) |
Protein name |
Protein phosphatase 1 regulatory subunit 7 |
Names |
Protein phosphatase 1 regulatory subunit 22 |
Species |
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) |
KEGG Pathway |
xtr:448394 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6DIQ3
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6DIQ3-F1 | Predicted | AlphaFoldDB |
No variants for Q6DIQ3
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q6DIQ3 | |||||
No associated diseases with Q6DIQ3
18 regional properties for Q6DIQ3
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| repeat | Leucine-rich repeat | 107 - 128 | IPR001611-1 |
| repeat | Leucine-rich repeat | 129 - 150 | IPR001611-2 |
| repeat | Leucine-rich repeat | 151 - 172 | IPR001611-3 |
| repeat | Leucine-rich repeat | 173 - 194 | IPR001611-4 |
| repeat | Leucine-rich repeat | 195 - 216 | IPR001611-5 |
| repeat | Leucine-rich repeat | 217 - 238 | IPR001611-6 |
| repeat | Leucine-rich repeat | 239 - 260 | IPR001611-7 |
| repeat | Leucine-rich repeat | 261 - 282 | IPR001611-8 |
| repeat | Leucine-rich repeat, typical subtype | 105 - 126 | IPR003591-1 |
| repeat | Leucine-rich repeat, typical subtype | 127 - 148 | IPR003591-2 |
| repeat | Leucine-rich repeat, typical subtype | 149 - 170 | IPR003591-3 |
| repeat | Leucine-rich repeat, typical subtype | 171 - 193 | IPR003591-4 |
| repeat | Leucine-rich repeat, typical subtype | 215 - 236 | IPR003591-5 |
| repeat | Leucine-rich repeat, typical subtype | 237 - 259 | IPR003591-6 |
| domain | U2A'/phosphoprotein 32 family A, C-terminal | 183 - 197 | IPR003603-1 |
| domain | U2A'/phosphoprotein 32 family A, C-terminal | 322 - 340 | IPR003603-2 |
| repeat | Leucine rich repeat 4 | 107 - 147 | IPR025875-1 |
| repeat | Leucine rich repeat 4 | 196 - 236 | IPR025875-2 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
| protein phosphatase type 1 complex | A protein complex that possesses magnesium-dependent protein serine/threonine phosphatase (AMD phosphatase) activity, and consists of a catalytic subunit and one or more regulatory subunits that dictates the phosphatase's substrate specificity, function, and activity. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| protein serine/threonine phosphatase inhibitor activity | Binds to and stops, prevents or reduces the activity of a serine/threonine protein phosphatase, an enzyme that catalyzes the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| positive regulation of protein dephosphorylation | Any process that activates or increases the frequency, rate or extent of removal of phosphate groups from a protein. |
7 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q8IYG6 | LRRC56 | Leucine-rich repeat-containing protein 56 | Homo sapiens (Human) | PR |
| Q96M69 | LRGUK | Leucine-rich repeat and guanylate kinase domain-containing protein | Homo sapiens (Human) | PR |
| Q9H069 | DRC3 | Dynein regulatory complex subunit 3 | Homo sapiens (Human) | PR |
| Q4LDG9 | DNAL1 | Dynein axonemal light chain 1 | Homo sapiens (Human) | PR |
| Q6ZRR7 | LRRC9 | Leucine-rich repeat-containing protein 9 | Homo sapiens (Human) | PR |
| Q9DAP0 | Lrrc46 | Leucine-rich repeat-containing protein 46 | Mus musculus (Mouse) | PR |
| Q9D5S7 | Lrguk | Leucine-rich repeat and guanylate kinase domain-containing protein | Mus musculus (Mouse) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MADEEGETEV | QEMEVDRRES | DESADDEAKE | KPDRVDGGVK | NGEVPLGEAD | APVDIETINL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| DPEAEDVDLN | HFKIGKIQGF | EVLKKVKTLC | LRQNLIKLIE | NLEQLVTLTE | LDLYDNQIRK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| IGNLETLRDL | QILDLSFNLL | RRIEGLESLS | HLQRLYLVNN | KISRIENFGT | LTQLRLLELG |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SNRLRVIENL | DSLRELDSLF | LGKNKITKLQ | NLETLTNLTV | LSVQSNRLTK | IEGLQNLVNL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| RELYLSDNGI | QVIEGLENNN | KLTTLDLASN | RIKRIENIKH | LSELQEFWMN | DNLVENWSDL |
| 310 | 320 | 330 | 340 | ||
| EELSGAPGLQ | TVYLERNPLQ | KDAQYRRKIM | LALPSVRQID | ATFVRF |