Q6AYH0

PR
Gene name
Miip (Iip45)
Protein name
Migration and invasion-inhibitory protein
Names
Invasion-inhibitory protein 45, IIp45
Species
Rattus norvegicus (Rat)
KEGG Pathway
rno:298643
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

15-95 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6AYH0

Entry ID Method Resolution Chain Position Source
AF-Q6AYH0-F1 Predicted AlphaFoldDB

No variants for Q6AYH0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6AYH0

No associated diseases with Q6AYH0

No regional properties for Q6AYH0

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q6AYH0

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

2 GO annotations of biological process

Name Definition
negative regulation of cell migration Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration.
negative regulation of G2/M transition of mitotic cell cycle Any signalling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
A2A7Y5 Miip Migration and invasion-inhibitory protein Mus musculus (Mouse) PR
Q6AYH0 Miip Migration and invasion-inhibitory protein Rattus norvegicus (Rat) PR
10 20 30 40 50 60
MTNMAETKDT VQLRLLSLEL LKQLWAGHEA MCQSVTRAAS ESNLDYSSSS NNLEMPLSQE
70 80 90 100 110 120
TSASSVAPNS QDKRHVWDPL DSHRGDTYDV AWYGKVNSRV DSLPPATCQH QEPQEGLRPS
130 140 150 160 170 180
SVPLLATEGL KRPVSLGGPK GLGPDKAQVP RSLPLRLGKL SKPKVTFSQE SSVPESSWYS
190 200 210 220 230 240
RPCLDYDWTA GSLDSSSPVS SESEAYFSML QRFREDNRED CVCNSPEAVF PELQESSGVE
250 260 270 280 290 300
EDHECVYCYR INRRLFPEPL DPGAPCCLCG IPRDEQGPQT LVEPVQVRVS IPLSIMDPPH
310 320 330 340 350 360
QYRIHRRKSF DASDTFALPR HCLLGWDILP PKSEKTSVPK SLDLWSSVSH GAAQRRNLSA
370 380
TNPSYQALRS RVPPPFWSEP QVARLCPSH