A2A7Y5
Gene name |
Miip (D4Wsu114e, Iip45) |
Protein name |
Migration and invasion-inhibitory protein |
Names |
CLM-6, CD300 antigen-like family member C, Invasion-inhibitory protein 45, IIp45 |
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:28010 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A2A7Y5
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A2A7Y5-F1 | Predicted | AlphaFoldDB |
33 variants for A2A7Y5
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs3388717681 | 9 | D>N | No | EVA | |
| rs3394961463 | 18 | L>Q | No | EVA | |
| rs3394508626 | 27 | G>E | No | EVA | |
| rs3395115686 | 31 | M>V | No | EVA | |
| rs3388706326 | 37 | R>S | No | EVA | |
| rs3388733463 | 38 | A>V | No | EVA | |
| rs3388732921 | 39 | A>V | No | EVA | |
| rs3395204370 | 81 | S>I | No | EVA | |
| rs3394898010 | 84 | D>G | No | EVA | |
| rs3394961505 | 93 | V>G | No | EVA | |
| rs3388733399 | 97 | S>F | No | EVA | |
| rs3388732932 | 111 | E>* | No | EVA | |
| rs3388732966 | 114 | E>G | No | EVA | |
| rs3395123562 | 119 | P>L | No | EVA | |
| rs3395060183 | 123 | L>* | No | EVA | |
| rs3388732945 | 154 | S>T | No | EVA | |
| rs3388728187 | 157 | S>R | No | EVA | |
| rs3388731810 | 160 | S>T | No | EVA | |
| rs3388726098 | 186 | W>* | No | EVA | |
| rs3388728175 | 193 | N>S | No | EVA | |
| rs3388728229 | 195 | S>F | No | EVA | |
| rs3395204359 | 225 | E>A | No | EVA | |
| rs3388720005 | 241 | H>L | No | EVA | |
| rs3395123594 | 242 | E>D | No | EVA | |
| rs3388717668 | 262 | A>P | No | EVA | |
| rs3388733412 | 297 | P>L | No | EVA | |
| rs3388732967 | 299 | Q>K | No | EVA | |
| rs3395204397 | 299 | Q>R | No | EVA | |
| rs3388730129 | 310 | A>V | No | EVA | |
| rs3388733244 | 326 | I>N | No | EVA | |
| rs3388735519 | 330 | K>N | No | EVA | |
| rs3388737550 | 355 | D>Y | No | EVA | |
| rs3388731838 | 380 | V>I | No | EVA |
No associated diseases with A2A7Y5
No regional properties for A2A7Y5
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for A2A7Y5 | |||
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| negative regulation of cell migration | Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration. |
| negative regulation of G2/M transition of mitotic cell cycle | Any signalling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q6AYH0 | Miip | Migration and invasion-inhibitory protein | Rattus norvegicus (Rat) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MPNMAETKDP | VRLRLLSLEL | LKQLWAGHEA | MCRSVVRAAS | GSNLDCSSNN | LEMPLSQETS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SASSVAPSSQ | DKRHMLDPLD | SRRDDTFDVA | WYVKFNSRMD | SFLPATGQHQ | EPQEELRPPS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VPLLATQGLK | GPVSLGGPKG | LGPDKTQVPR | SILSRLSKPS | KPRVTSQESA | VPESSWHSRP |
| 190 | 200 | 210 | 220 | 230 | 240 |
| YLGYDWIAGS | LDNSSPVTSE | PEAFFSMLQR | FRENNKEDCV | CNSPEAVFPG | LQESSGVEED |
| 250 | 260 | 270 | 280 | 290 | 300 |
| HECMYCYRIN | RRLFPEPVDP | GAPCRLCGIP | RDEKGPGTLV | EPVQVRVSIP | LSIMDPPHQY |
| 310 | 320 | 330 | 340 | 350 | 360 |
| RIHRRKSFDA | SDTLALPRHC | LLGWDILPPK | SEKTSVPKSL | DLWSSVSYGA | GQRRDLSATS |
| 370 | 380 | ||||
| PPCQALPAQV | TPPLWSEPQV | AQLCPSH |