Q6AY52

PR
Gene name
Spacdr
Protein name
Sperm acrosome developmental regulator
Names
Species
Rattus norvegicus (Rat)
KEGG Pathway
rno:100362783
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

142-200 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6AY52

Entry ID Method Resolution Chain Position Source
AF-Q6AY52-F1 Predicted AlphaFoldDB

No variants for Q6AY52

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6AY52

No associated diseases with Q6AY52

No regional properties for Q6AY52

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q6AY52

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasmic vesicle, secretory vesicle, acrosome
  • Detected in acrosome of round spermatids and spermatozoa
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
acrosomal vesicle A structure in the head of a spermatozoon that contains acid hydrolases, and is concerned with the breakdown of the outer membrane of the ovum during fertilization. It lies just beneath the plasma membrane and is derived from the lysosome.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
spermatid development The process whose specific outcome is the progression of a spermatid over time, from its formation to the mature structure.

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q2T9X5 SPACDR Sperm acrosome developmental regulator Bos taurus (Bovine) PR
Q8IZ16 SPACDR Sperm acrosome developmental regulator Homo sapiens (Human) PR
Q6AY52 Spacdr Sperm acrosome developmental regulator Rattus norvegicus (Rat) PR
10 20 30 40 50 60
MRFLRWIRQI WRKVPNWVLF WKHLAKPGLS DQREKHLLKG PEKTSKDFDT VKLANAQKED
70 80 90 100 110 120
MVSDLDVCPG VLRSVKERSP LHDRESRSSR DSRSLMTVVN SVSTFMFSVL QSGWRLCRWK
130 140 150 160 170 180
SSMSTGKVSS HTRTGSALGT PEAEMLREVY LVLWVIRKQL RELARRQERR RRRRMRSHAS
190
HTSRHSESVQ GLKHDARSPL