Q5ZLD2

PR
Gene name
DEPDC1B (RCJMB04_6k16)
Protein name
DEP domain-containing protein 1B
Names
Species
Gallus gallus (Chicken)
KEGG Pathway
gga:427152
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

74-171 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5ZLD2

Entry ID Method Resolution Chain Position Source
AF-Q5ZLD2-F1 Predicted AlphaFoldDB

No variants for Q5ZLD2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5ZLD2

No associated diseases with Q5ZLD2

2 regional properties for Q5ZLD2

Type Name Position InterPro Accession
domain Rho GTPase-activating protein domain 192 - 393 IPR000198
domain DEP domain 24 - 108 IPR000591

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
GTPase activator activity Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.

2 GO annotations of biological process

Name Definition
intracellular signal transduction The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
positive regulation of Wnt signaling pathway Any process that activates or increases the frequency, rate or extent of Wnt signal transduction.

4 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q5TB30 DEPDC1 DEP domain-containing protein 1A Homo sapiens (Human) PR
Q8WUY9 DEPDC1B DEP domain-containing protein 1B Homo sapiens (Human) PR
Q8BH88 Depdc1b DEP domain-containing protein 1B Mus musculus (Mouse) PR
Q21341 let-99 Protein let-99 Caenorhabditis elegans PR
10 20 30 40 50 60
MEPGLVGPGP YRATRLWNEI IELFRAGMPL RKHRCRFKSY ERCFKASEAV DCLHELLGSN
70 80 90 100 110 120
QNFGPEVTRS QTVKLLKKFL KNHVIEDIKG RWGKEDFQDD GHLYRFPPSS PLKPYPKKPS
130 140 150 160 170 180
FGKEVIKFPD WDDPKAGTSQ EHIPVKSIMM NSETWYKRHS IAIGEVPACK LVFRRELTQE
190 200 210 220 230 240
NIEEIWKSMT LARLQKVLGL DCLDEVIDTK LVNSKHIVQN AYNVNKQGIV TLEDKSKDLP
250 260 270 280 290 300
HWILSAMKCL ANWPICSDLK QPTYSGFERD VFKTIVDYFG QMKEPLLTFN FFDVFVSVLG
310 320 330 340 350 360
LLQKHNEAIE ALQISCLLLP PESRRKLQLL VRMMARISFN KDLPPLSESV RTRVLMVQAF
370 380 390 400 410 420
SRCILCSKDE MDLDELLAAK LVSFLMDNYQ EILSVPSSLK SSIEEHVVHV QRVQIKYAGA
430 440 450 460 470 480
DTDAAFPAPS FCHQISTDEF EYQRATGSQE PLAALLEEIA TNKEISVKDK KKKLKQFQKS
490 500 510 520
YPEVYRVRFP TPETEAVLFP EKSKQKPPLL MWALRKPFQP FHRTRSFRM