Q5U2R5
Gene name |
Ppp1r3c |
Protein name |
Protein phosphatase 1 regulatory subunit 3C |
Names |
Protein phosphatase 1 regulatory subunit 5, PP1 subunit R5, Protein targeting to glycogen, PTG |
Species |
Rattus norvegicus (Rat) |
KEGG Pathway |
rno:309513 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q5U2R5
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q5U2R5-F1 | Predicted | AlphaFoldDB |
No variants for Q5U2R5
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q5U2R5 | |||||
No associated diseases with Q5U2R5
No regional properties for Q5U2R5
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q5U2R5 | |||
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| glycogen granule | Cytoplasmic bead-like structures of animal cells, visible by electron microscope. Each granule is a functional unit with the biosynthesis and catabolism of glycogen being catalyzed by enzymes bound to the granule surface. |
| intracellular membrane-bounded organelle | Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. |
| protein phosphatase type 1 complex | A protein complex that possesses magnesium-dependent protein serine/threonine phosphatase (AMD phosphatase) activity, and consists of a catalytic subunit and one or more regulatory subunits that dictates the phosphatase's substrate specificity, function, and activity. |
6 GO annotations of molecular function
| Name | Definition |
|---|---|
| [phosphorylase] phosphatase activity | Catalysis of the reaction: |
| enzyme binding | Binding to an enzyme, a protein with catalytic activity. |
| glycogen binding | Binding to glycogen. |
| molecular adaptor activity | The binding activity of a molecule that brings together two or more molecules through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way. |
| protein phosphatase 1 binding | Binding to a protein phosphatase 1. |
| protein phosphatase binding | Binding to a protein phosphatase. |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| glycogen biosynthetic process | The chemical reactions and pathways resulting in the formation of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues. |
| glycogen metabolic process | The chemical reactions and pathways involving glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues in alpha-(1->4) glycosidic linkage, joined together by alpha-(1->6) glycosidic linkages. |
| regulation of glycogen biosynthetic process | Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen. |
| regulation of glycogen catabolic process | Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen. |
3 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q80W88 | Homez | Homeobox and leucine zipper protein Homez | Mus musculus (Mouse) | PR |
| Q8K3E9 | Homez | Homeobox and leucine zipper protein Homez | Rattus norvegicus (Rat) | PR |
| Q6P950 | ppp1r3cb | Protein phosphatase 1 regulatory subunit 3C-B | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSCTRMIHVL | DPRPLTSSVM | PVDMAMRICL | AHSPPLKSFL | GPYNGLQRRH | FVNKPKPLKP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| CLSVKQEAKS | QKEWKSPHSQ | AKKRVVFADS | KGLSLTAIHV | FSDLPEEPAW | DLQFDLLDLN |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DISSSLKLHE | EKNLVFDFPQ | PSSDYLSFRD | RFQKNFVCLE | NCSLQDRTVT | GTVKVKNVSF |
| 190 | 200 | 210 | 220 | 230 | 240 |
| EKKVQVRITF | DTWKTYTDVD | CVYLKNVYGS | SDSDTFSFAI | DLPRVIPTEE | KIEFCISYHA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| NGRVFWDNNE | AQNYRIVHVQ | WKPDGVQTQV | APKDCAFQQV | PLKTELEPTV | FGSPRLASGL |
| 310 | |||||
| FPEWQSWGRV | ENLASYR |