Q5SPP5

PR
Gene name
efr3b (si:ch211-203k16.1, si:ch211-215m21.18)
Protein name
Protein EFR3 homolog B
Names
Species
Danio rerio (Zebrafish) (Brachydanio rerio)
KEGG Pathway
dre:561353
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

177-258 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5SPP5

Entry ID Method Resolution Chain Position Source
AF-Q5SPP5-F1 Predicted AlphaFoldDB

No variants for Q5SPP5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5SPP5

No associated diseases with Q5SPP5

No regional properties for Q5SPP5

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q5SPP5

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Lipid-anchor
  • Palmitoylation anchors the protein to the plasma membrane
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

2 GO annotations of biological process

Name Definition
phosphatidylinositol phosphate biosynthetic process The chemical reactions and pathways resulting in the formation of phosphatidylinositol phosphate.
protein localization to plasma membrane A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane.

4 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q14156 EFR3A Protein EFR3 homolog A Homo sapiens (Human) PR
Q9Y2G0 EFR3B Protein EFR3 homolog B Homo sapiens (Human) PR
Q8BG67 Efr3a Protein EFR3 homolog A Mus musculus (Mouse) PR
Q6ZQ18 Efr3b Protein EFR3 homolog B Mus musculus (Mouse) PR
10 20 30 40 50 60
MTGVCGCCGA LRPRYKRLVD NIFPEDPEDG LVKANMEKLT FYALSAPEKL DRIGAYLSER
70 80 90 100 110 120
LSRDVARHRY GYVCIAMEAL DQLLMACHCQ SINLFVESFL KMVRKLLEAD KPNLQILGTN
130 140 150 160 170 180
SFVKFANIEE DTPSYHRSYD FFVSRFSEMC HSGYEDPDIR TKIRMAGIKG LQGVVRKTVN
190 200 210 220 230 240
DELQANIWDP QHMDKIVPSL LFNLQSGEGT ESRSPSPLQA SEKEKESPAE LTERCFRELL
250 260 270 280 290 300
GRAAYGNIKN AVTPVLMHLD NHSLWEGKTF AVRCFKIIMY SIQSQHSHLV IQQLLGHLDA
310 320 330 340 350 360
NSKSSATVRA GIVEVLLEVA AIAASGSVGP TVLEVFNTLL RHLRLSVDYE LTGSYDCTNI
370 380 390 400 410 420
GTKIIKEHEE RQLQEAVIRT IGSFANTLPT YQRSEVMLFI MGKVPIPGLH PTLPSIGSGP
430 440 450 460 470 480
EGNRMIQVML LKSLRQVTCG FQTTNMLTAL PNSFLDPMLS FALLEDAEIR LLVLEILVSL
490 500 510 520 530 540
IDRHDNLPKF SNISIISDIS VLKLKVDKCS RQDNLFMKKH AQHLYRHIYL CSKEQSSVQP
550 560 570 580 590 600
HFEKLYSLLA LISMELANEE VVVDLIRVAL ALQDLALSSE EMLPVYNRCA IHALSSAYLN
610 620 630 640 650 660
LISQLTTVPA FCQHVHEVIE MRQKEIPYLL PEDVFIENPK IPKTLEKLEG DVLFQQAKIT
670 680 690 700 710 720
EVLGGSGYNT ERLATPYVPQ FTDEDRLSKR KSIGETISLQ VEVDSRNSPE KEERTPAEEI
730 740 750 760 770 780
TFETLKNAIV DSVGVEEQEK ERRRQVVEKF QKAPFEEIAA HCGARATMLQ SKLNQIFEIT
790 800 810
IRPPPSPSGT ITSSYGQTQS RSVPVYEMKF PDLCVY