Q5H9J9

PR
Gene name
TCP11X2
Protein name
T-complex protein 11 X-linked protein 2
Names
Species
Homo sapiens (Human)
KEGG Pathway
hsa:100996648
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

258-342 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5H9J9

Entry ID Method Resolution Chain Position Source
AF-Q5H9J9-F1 Predicted AlphaFoldDB

No variants for Q5H9J9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5H9J9

No associated diseases with Q5H9J9

No regional properties for Q5H9J9

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q5H9J9

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
acrosomal vesicle A structure in the head of a spermatozoon that contains acid hydrolases, and is concerned with the breakdown of the outer membrane of the ovum during fertilization. It lies just beneath the plasma membrane and is derived from the lysosome.
sperm flagellum A microtubule-based flagellum (or cilium) that is part of a sperm, a mature male germ cell that develops from a spermatid.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

3 GO annotations of biological process

Name Definition
protein kinase A signaling A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase A, which occurs as a result of a single trigger reaction or compound.
regulation of sperm capacitation Any process that modulates the frequency, rate or extent of sperm capacitation.
signal transduction The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q8N4U5 TCP11L2 T-complex protein 11-like protein 2 Homo sapiens (Human) PR
Q8WWU5 TCP11 T-complex protein 11 homolog Homo sapiens (Human) PR
Q5H9J9 TCP11X2 T-complex protein 11 X-linked protein 2 Homo sapiens (Human) PR
10 20 30 40 50 60
MYNAFWNHLK EQLLSTPPDF TCALELLKDV KENRLRNEIE EALDTDLLKQ EAEHGALDVP
70 80 90 100 110 120
HLSNYILNLM ALLCAPVRDE AIQKLETIRD PVQLLRGILR VLGLMKMDMV NYTIQSFRPY
130 140 150 160 170 180
LQEHSIQYEQ AKFQELLDKQ PSLLDYTTKW LTKAATDITT LCPSSPDSPS SSCSMACSLP
190 200 210 220 230 240
SGAGNNSEPP SPTMVLYQGY LNLLLWDLEN VEFPETLLMD RIRLQELAFQ LHQLTVLASV
250 260 270 280 290 300
LLVARSFSGE VLFRSPEFVD RLKCTTKALT EEFISRPEET MLSVSEQVSQ EVHQGLKDMG
310 320 330 340 350 360
LTTLSSENTA SLLGQLQNIT KKENCIRSIV DQWIRFFLKC CLLHGMQESL LHFPGGLILI
370 380 390 400
EKELAELGWK FLNLMHHNQQ VFGPYYAEIL KHIIHPAQAQ ETDVEPN