Q5F3A1

PR
Gene name
SEC62 (TLOC1, RCJMB04_25p9)
Protein name
Translocation protein SEC62
Names
Translocation protein 1, TP-1
Species
Gallus gallus (Chicken)
KEGG Pathway
gga:424993
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

76-181 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5F3A1

Entry ID Method Resolution Chain Position Source
AF-Q5F3A1-F1 Predicted AlphaFoldDB

6 variants for Q5F3A1

Variant ID(s) Position Change Description Diseaes Association Provenance
rs733038921 14 V>G No Ensembl
rs738677737 115 A>S No Ensembl
rs734523831 281 L>P No Ensembl
rs732482611 282 Y>D No Ensembl
rs737216225 286 Y>N No Ensembl
rs740063263 396 E>K No Ensembl

No associated diseases with Q5F3A1

No regional properties for Q5F3A1

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q5F3A1

Functions

Description
EC Number
Subcellular Localization
  • Endoplasmic reticulum membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
endoplasmic reticulum The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
integral component of endoplasmic reticulum membrane The component of the endoplasmic reticulum membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
post-translational protein targeting to membrane, translocation The process in which a protein translocates through the ER membrane posttranslationally.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q99442 SEC62 Translocation protein SEC62 Homo sapiens (Human) PR
Q8BU14 Sec62 Translocation protein SEC62 Mus musculus (Mouse) PR
10 20 30 40 50 60
MAERRRHRKR IQEVGEPFKE EKAVAKYLRF NCPTKSTNMM GHRVDYFIAS KAVDCLLDSK
70 80 90 100 110 120
WAKAKKGEEA LFTTRESVVD YCNRLLKKQF FHRALKVMKM KPDKDTKKEK EKGKAESGKE
130 140 150 160 170 180
EEKKSKKESS KDEKTKKEKE KKKDGEKEEC KKDETPGTPK KKETKRKFKL EPHEDQVFLD
190 200 210 220 230 240
GNEVYVWIYD PVHFKTFAMG LVLVIAVIAA TLFPLWPAEM RVGVYYLSVG AGCFVASILL
250 260 270 280 290 300
LAVARCILFL IIWLITGGRH HFWFLPNLTA DVGFIDSFRP LYTHEYKGPK ADLKKEEKSE
310 320 330 340 350 360
SKKQQKYDSE EKSDSEKKEE EDGKTEATRN SGTEGSGGER HSDTDSDRRE DDRSQHSSGN
370 380 390
GNDFEMITKE ELEQQTDEGD CEEDEDEDTE SRPSHEKS