Q5BL81

PR
Gene name
slc5a8
Protein name
Sodium-coupled monocarboxylate transporter 1
Names
Electrogenic sodium monocarboxylate cotransporter, Solute carrier family 5 member 8
Species
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

542-620 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5BL81

Entry ID Method Resolution Chain Position Source
AF-Q5BL81-F1 Predicted AlphaFoldDB

No variants for Q5BL81

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5BL81

No associated diseases with Q5BL81

1 regional properties for Q5BL81

Type Name Position InterPro Accession
domain Exocyst complex component Sec8, N-terminal 45 - 143 IPR007191

Functions

Description
EC Number
Subcellular Localization
  • Apical cell membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

1 GO annotations of molecular function

Name Definition
symporter activity Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.

1 GO annotations of biological process

Name Definition
sodium ion transport The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q2M3M2 SLC5A9 Sodium/glucose cotransporter 4 Homo sapiens (Human) PR
Q49B93 Slc5a12 Sodium-coupled monocarboxylate transporter 2 Mus musculus (Mouse) PR
Q63008 Slc5a5 Sodium/iodide cotransporter Rattus norvegicus (Rat) PR
10 20 30 40 50 60
MVTPGNIGSF TVWDYVVFAL MLLISAVIGI YYAFAGGGQK TSKDFLMGGR SMTAVPVALS
70 80 90 100 110 120
LTASFMSAVT VLGTPAEVYR FGSMFSIFAF TYAIVVVISS EVFLPVFYRL GITSTYEYLE
130 140 150 160 170 180
LRFNKFVRLL GTILFIIQTV LYTGIVIYAP ALALNQVTGF DLWGAVVATG VVCTFYCTMG
190 200 210 220 230 240
GLKAVVWTDV FQVGIMVAGF SSVIIRAVVV QGGIGPILND SYYGDRLNFW DFTPNPLQRH
250 260 270 280 290 300
SFWTIVVGGT FTWTGIYGVN QSQVQRYIAC KTRFQAKLSL YINLLGLWAI LACAVLSGLA
310 320 330 340 350 360
MYSIYKDCDP WTAQFVSAPD QLMPYLSLDI LRDYPGLPGL FVSCAYSGTL STVSSSINAL
370 380 390 400 410 420
AAVTVEDLIK PYFRSLSETK MSWISKGTSL IYGAICIAMA GLASLMGGLL QAALSIFGMV
430 440 450 460 470 480
GGPLLGLFAL GIIFPFVNSL GAVIGLLSGF AISLWVGIGS QIYPPTASSS LPKPLSLEGC
490 500 510 520 530 540
NFTSFESNWT TTVMPMMTTL IPEVSSRPEL ADSWYSLSYL YFSTLGTIVA VVVGVIASLL
550 560 570 580 590 600
SGGLKQNVNR DFLLTSQDFS YLNVLFSNCK KKGQEEKVEV LNWKMRSTDT DMDQGTDNPA
610
FNHMEMSSTE KKEKMNGIIA