Q42064

PR
Gene name
RPL8C (At4g36130, F23E13.20, T19K4.260)
Protein name
60S ribosomal protein L8-3
Names
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT4G36130
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-56 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q42064

Entry ID Method Resolution Chain Position Source
AF-Q42064-F1 Predicted AlphaFoldDB

1 variants for Q42064

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_4_17098555_C_T 226 R>C No 1000Genomes

No associated diseases with Q42064

3 regional properties for Q42064

Type Name Position InterPro Accession
domain Ribosomal Proteins L2, RNA binding domain 13 - 89 IPR022666
domain Ribosomal protein L2, C-terminal 96 - 231 IPR022669
conserved_site Ribosomal protein L2, conserved site 197 - 208 IPR022671

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

5 GO annotations of cellular component

Name Definition
cytosolic large ribosomal subunit The large subunit of a ribosome located in the cytosol.
cytosolic ribosome A ribosome located in the cytosol.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
polysomal ribosome A ribosome bound to mRNA that forms part of a polysome.
vacuole A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.

3 GO annotations of molecular function

Name Definition
mRNA binding Binding to messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
RNA binding Binding to an RNA molecule or a portion thereof.
structural constituent of ribosome The action of a molecule that contributes to the structural integrity of the ribosome.

1 GO annotations of biological process

Name Definition
cytoplasmic translation The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein.

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9XVF7 rpl-2 60S ribosomal protein L8 Caenorhabditis elegans PR
P0DKI4 PUX14 Putative plant UBX domain-containing protein 14 Arabidopsis thaliana (Mouse-ear cress) PR
P46286 RPL8A 60S ribosomal protein L8-1 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MGRVIRAQRK GAGSVFKSHT HHRKGPAKFR SLDFGERNGY LKGVVTEIIH DPGRGAPLAR
70 80 90 100 110 120
VAFRHPFRFK KQKELFVAAE GMYTGQFLYC GKKATLVVGN VLPLRSIPEG AVICNVEHHV
130 140 150 160 170 180
GDRGVFARAS GDYAIVIAHN PDNDTSRIKL PSGSKKIVPS GCRAMIGQVA GGGRTEKPML
190 200 210 220 230 240
KAGNAYHKYR VKRNCWPKVR GVAMNPVEHP HGGGNHQHIG HASTVRRDAP PGKKVGLIAA
250
RRTGRLRGQA AALASKAD