Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P0DKI4
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P0DKI4-F1 | Predicted | AlphaFoldDB |
No variants for P0DKI4
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P0DKI4 | |||||
No associated diseases with P0DKI4
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| ubiquitin binding | Binding to ubiquitin, a protein that when covalently bound to other cellular proteins marks them for proteolytic degradation. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| proteasome-mediated ubiquitin-dependent protein catabolic process | The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome. |
4 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q06682 | UBX5 | UBX domain-containing protein 5 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| Q9XVF7 | rpl-2 | 60S ribosomal protein L8 | Caenorhabditis elegans | PR |
| P46286 | RPL8A | 60S ribosomal protein L8-1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q42064 | RPL8C | 60S ribosomal protein L8-3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| METATRTHQQ | RKLISSFLDI | TVNQTVEIAT | QFLEATTWNL | EDAINLFLIA | RRNPHHHHGE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ELVPLPLPSK | KNTLYDYDPF | MSHNTSVAVC | PEEIWDDEST | SEESDSRLSS | LYRPPPSLFF |
| 130 | 140 | 150 | 160 | 170 | 180 |
| HGSFEDAKAT | SSREDLWLLV | NLQSTTEFAS | HLLNRDLWPH | DAVFQAIKSS | FILLQVYDDT |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SEGQKISTFY | KIDSVPPVVL | LIDPITGQKM | RMWSGVIEPQ | GFLEDLMKYM | DSGPHEHVAS |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LTSNKRMKTE | KISCSSNNAD | DQDMATFWGN | AIEEEKTVIK | SGKEETFTSD | RVVAPSWGPE |
| 310 | 320 | 330 | 340 | 350 | 360 |
| FEDIMTLSEH | EEETCLSCDL | LEFPVLTEEP | KADCDRSVVC | SICVRFPDGR | RKQRKFLKSE |
| 370 | 380 | 390 | 400 | 410 | |
| PIQLLWSFCY | SHMEESEKKE | FKLVQAIPGA | SKTLDYGAKA | TFDQSGIANS | MISVTWE |