Q3ZRW6

PR
Gene name
Clul1
Protein name
Clusterin-like protein 1
Names
Species
Mus musculus (Mouse)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-129 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q3ZRW6

Entry ID Method Resolution Chain Position Source
AF-Q3ZRW6-F1 Predicted AlphaFoldDB

No variants for Q3ZRW6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q3ZRW6

No associated diseases with Q3ZRW6

2 regional properties for Q3ZRW6

Type Name Position InterPro Accession
domain Clusterin, N-terminal 26 - 235 IPR016014
domain Clusterin, C-terminal 236 - 458 IPR016015

Functions

Description
EC Number
Subcellular Localization
  • Secreted
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
extracellular space That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

1 GO annotations of molecular function

Name Definition
misfolded protein binding Binding to a misfolded protein.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q95KN1 CLUL1 Clusterin-like protein 1 Canis lupus familiaris (Dog) (Canis familiaris) PR
Q06890 Clu Clusterin Mus musculus (Mouse) PR
Q3ZRW7 Clul1 Clusterin-like protein 1 Rattus norvegicus (Rat) PR
10 20 30 40 50 60
MQPPLLVLSV YLLWLKYCDS APTWKETDAT DGNLKSLPEV GEADVEGEVK KALIGIKQMK
70 80 90 100 110 120
IMMERREEEH AKLMKALKKC KEEKQEAQKL MNEVQERLEE EEKLCQASSI GSWDGCRPCL
130 140 150 160 170 180
ESNCIRFYTA CQPGWSSVKS MMKQFLKKIY RFLSSQSEDV KDPPAIEQLT KEDLQVVHIE
190 200 210 220 230 240
NLFSQLAVDA KSLFNMSFYI FKQMQHEFDQ AFQLYFMSDV DLMEPYPPAL SKEITKKEEL
250 260 270 280 290 300
GQRWGIPNVF QLFHNFSLSV YGRVQQIIMK TLNAIEDSWE PHKELDQRGM TSEMLPEQNG
310 320 330 340 350 360
EMCEEFVKNL SGCLKFRKRC QKCHNYLSEE CPDVPELHIE FLEALKLVNV SNQQYDQIVQ
370 380 390 400 410 420
MTQYHLEDTI YLMEKMQEQF GWVSQLASHN PVTEDIFNST KAVPKIHGGD SSKQDEIMVD
430 440 450 460
SSSILPSSNF TVQNPPEEGA ESSSTIYYIV AKVLQHFKGH FKTW