Q95KN1

PR
Gene name
CLUL1
Protein name
Clusterin-like protein 1
Names
Retinal-specific clusterin-like protein
Species
Canis lupus familiaris (Dog) (Canis familiaris)
KEGG Pathway
cfa:403747
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-129 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q95KN1

Entry ID Method Resolution Chain Position Source
AF-Q95KN1-F1 Predicted AlphaFoldDB

No variants for Q95KN1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q95KN1

No associated diseases with Q95KN1

2 regional properties for Q95KN1

Type Name Position InterPro Accession
domain Clusterin, N-terminal 26 - 237 IPR016014
domain Clusterin, C-terminal 238 - 459 IPR016015

Functions

Description
EC Number
Subcellular Localization
  • Secreted
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
extracellular space That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

1 GO annotations of molecular function

Name Definition
misfolded protein binding Binding to a misfolded protein.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P25473 CLU Clusterin Canis lupus familiaris (Dog) (Canis familiaris) PR
Q3ZRW6 Clul1 Clusterin-like protein 1 Mus musculus (Mouse) PR
Q3ZRW7 Clul1 Clusterin-like protein 1 Rattus norvegicus (Rat) PR
10 20 30 40 50 60
MKPSLLVFTV YLLWLKDCHC APTWKDKTDM HGNLKGFSEA GDIDVDEEVK KALIGMKQMK
70 80 90 100 110 120
IMMERREEEH TNLMKTLKKC KEEKQEALKL MNEVQEHLEE EESLCQVSLT DSWDECKSCL
130 140 150 160 170 180
ESNCMRFHTT CQPSWSSMKN TVEQFFRNIY QYLFPFDEDN EKDLPVGEKF IEEDAQVAQI
190 200 210 220 230 240
ENVFNQLTVD VRFLFNRSLN VFKQMQQEFD QTFQSYFMSD TDLMQPNFLP ALSKEPRKKA
250 260 270 280 290 300
DPVQSWDIPS FFQLFYNFSL SIYHSISTTI TKTLNAIEDL PKQDNDSNHG SLSSKTLPVQ
310 320 330 340 350 360
HRGPYGEFGQ NLSECFQFHA RCQKCQDYLW EDCPDVPELH TKVDEALELV NISHQQYAQV
370 380 390 400 410 420
LQMTQHHLED TTYLMEKMRE EFGWVADLAN QAPGAENIFD STKMVPNIHE GNFSKQDETM
430 440 450 460
IDLSILSSPN FTLKIPLEES AETSNFISYM LEKAVQHFKK HFKTW