Q3SYV3
Gene name |
OXA1L |
Protein name |
Mitochondrial inner membrane protein OXA1L |
Names |
Oxidase assembly 1-like protein, OXA1-like protein |
Species |
Bos taurus (Bovine) |
KEGG Pathway |
bta:520335 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q3SYV3
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q3SYV3-F1 | Predicted | AlphaFoldDB |
88 variants for Q3SYV3
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs208886389 | 4 | A>V | No | EVA | |
| rs210081490 | 14 | C>R | No | EVA | |
| rs433051573 | 18 | P>L | No | EVA | |
| rs434426433 | 37 | T>R | No | EVA | |
| rs472015677 | 42 | F>L | No | EVA | |
| rs433502161 | 45 | D>E | No | EVA | |
| rs464675458 | 48 | L>F | No | EVA | |
| rs451113823 | 49 | G>W | No | EVA | |
| rs437400037 | 50 | H>L | No | EVA | |
| rs468771579 | 50 | H>Q | No | EVA | |
| rs437400037 | 50 | H>R | No | EVA | |
| rs479900496 | 52 | R>L | No | EVA | |
| rs448488295 | 52 | R>S | No | EVA | |
| rs466212220 | 53 | Y>S | No | EVA | |
| rs477332205 | 54 | V>A | No | EVA | |
| rs463666267 | 58 | A>G | No | EVA | |
| rs481278346 | 60 | G>V | No | EVA | |
| rs723958843 | 66 | T>I | No | EVA | |
| rs440936736 | 66 | T>P | No | EVA | |
| rs472103645 | 70 | S>A | No | EVA | |
| rs452020959 | 74 | A>G | No | EVA | |
| rs434139559 | 76 | V>G | No | EVA | |
| rs468617509 | 77 | P>L | No | EVA | |
| rs463555749 | 81 | V>G | No | EVA | |
| rs477252849 | 81 | V>I | No | EVA | |
| rs454408818 | 84 | A>T | No | EVA | |
| rs440780398 | 84 | A>V | No | EVA | |
| rs453488383 | 85 | T>S | No | EVA | |
| rs433431003 | 86 | P>T | No | EVA | |
| rs457535135 | 88 | P>S | No | EVA | |
| rs437309964 | 90 | A>P | No | EVA | |
| rs437309964 | 90 | A>S | No | EVA | |
| rs448563439 | 91 | V>A | No | EVA | |
| rs448563439 | 91 | V>E | No | EVA | |
| rs468656171 | 91 | V>L | No | EVA | |
| rs479810636 | 93 | E>K | No | EVA | |
| rs477335295 | 94 | V>G | No | EVA | |
| rs445934531 | 94 | V>L | No | EVA | |
| rs449848077 | 97 | G>E | No | EVA | |
| rs460900859 | 98 | E>G | No | EVA | |
| rs440822999 | 101 | D>E | No | EVA | |
| rs458369733 | 102 | V>A | No | EVA | |
| rs472015521 | 102 | V>F | No | EVA | |
| rs472015521 | 102 | V>I | No | EVA | |
| rs472015521 | 102 | V>L | No | EVA | |
| rs471282599 | 103 | I>N | No | EVA | |
| rs437407839 | 105 | A>P | No | EVA | |
| rs475173225 | 108 | E>A | No | EVA | |
| rs455036182 | 109 | Q>E | No | EVA | |
| rs434863707 | 109 | Q>P | No | EVA | |
| rs466212187 | 112 | A>T | No | EVA | |
| rs446004568 | 114 | L>H | No | EVA | |
| rs432305142 | 115 | G>W | No | EVA | |
| rs470110385 | 116 | L>M | No | EVA | |
| rs481021791 | 117 | G>A | No | EVA | |
| rs481021791 | 117 | G>E | No | EVA | |
| rs481021791 | 117 | G>V | No | EVA | |
| rs460941886 | 118 | S>A | No | EVA | |
| rs447342687 | 119 | Y>H | No | EVA | |
| rs478511200 | 127 | N>K | No | EVA | |
| rs458506709 | 128 | L>F | No | EVA | |
| rs438369388 | 129 | L>F | No | EVA | |
| rs438369388 | 129 | L>I | No | EVA | |
| rs476170794 | 130 | E>K | No | EVA | |
| rs464086051 | 131 | F>L | No | EVA | |
| rs455123228 | 132 | M>I | No | EVA | |
| rs443851492 | 132 | M>L | No | EVA | |
| rs475238737 | 132 | M>R | No | EVA | |
| rs434902556 | 133 | H>N | No | EVA | |
| rs472667963 | 134 | V>F | No | EVA | |
| rs452483654 | 135 | N>T | No | EVA | |
| rs432377406 | 138 | L>R | No | EVA | |
| rs449978843 | 146 | A>E | No | EVA | |
| rs211399206 | 183 | I>V | No | EVA | |
| rs876281222 | 252 | W>G | No | EVA | |
| rs438324428 | 269 | V>I | No | EVA | |
| rs439334685 | 293 | M>R | No | EVA | |
| rs470690070 | 295 | N>T | No | EVA | |
| rs453456687 | 323 | N>D | No | EVA | |
| rs433308617 | 335 | I>S | No | EVA | |
| rs468533260 | 371 | N>I | No | EVA | |
| rs1115412792 | 381 | R>Q | No | EVA | |
| rs448433976 | 384 | R>P | No | EVA | |
| rs463465726 | 398 | R>G | No | EVA | |
| rs714141343 | 400 | T>M | No | EVA | |
| rs474449981 | 408 | Q>P | No | EVA | |
| rs442303814 | 421 | S>R | No | EVA | |
| rs473710781 | 432 | S>P | No | EVA |
No associated diseases with Q3SYV3
1 regional properties for Q3SYV3
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Membrane insertase YidC/Oxa/ALB, C-terminal | 140 - 332 | IPR028055 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of mitochondrial inner membrane | The component of the mitochondrial inner membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| mitochondrial membrane | Either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| membrane insertase activity | Binds transmembrane domain-containing proteins and mediates their integration into a membrane. |
| mitochondrial ribosome binding | Binding to a mitochondrial ribosome. |
| protein homodimerization activity | Binding to an identical protein to form a homodimer. |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| mitochondrial respiratory chain complex I assembly | The aggregation, arrangement and bonding together of a set of components to form mitochondrial respiratory chain complex I. |
| protein insertion into membrane | The process that results in the incorporation of a protein into a biological membrane. Incorporation in this context means having some part or covalently attached group that is inserted into the the hydrophobic region of one or both bilayers. |
| protein insertion into mitochondrial inner membrane from matrix | The process in which a protein is incorporated into the mitochondrial inner membrane from the matrix side. This includes membrane insertion of newly synthesized mitochondrially-encoded proteins, and insertion of nuclear-encoded proteins after their import into the mitochondrial matrix. |
| protein tetramerization | The formation of a protein tetramer, a macromolecular structure consisting of four noncovalently associated identical or nonidentical subunits. |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MALALMCGRR | QLLCLLRPQR | QFHSVAGPCQ | WPRKPLTAGL | GFPADRCLGH | PRYVLLMAPG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| PRGLSTSAVS | FGEAQVPAPP | VIPATPPPTA | VPEVASGEAA | DVIQAAAEQS | FAELGLGSYT |
| 130 | 140 | 150 | 160 | 170 | 180 |
| PVGLIQNLLE | FMHVNLGLPW | WGAIAACTVL | ARCLVFPLIV | KGQREAAKIH | NHLPEIQKFS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| ARIREAKLTG | NHTEFYRASS | EMTFYQKKHD | IKLFRPLILP | LTQAPIFISF | FIALREMANL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| PVPSLQTGGL | WWFQDLTLSD | PIYVLPLVVT | ATMWGVLELG | AETGMQSSDL | QWMRNFIRLM |
| 310 | 320 | 330 | 340 | 350 | 360 |
| PLAVLPITIH | FPTAVFMYWL | SSNMFSLGQV | ACLRIPAVRT | VLKIPQRVVH | DPDKLAPREG |
| 370 | 380 | 390 | 400 | 410 | 420 |
| FLKSFKQGWK | NAEMAHQLQE | RERRMQNHLE | LAARGPLRQT | FAHNPLLQHG | KNDPPNTPNS |
| 430 | 440 | ||||
| SSSSSSSNKA | KSKQPWRDTL | G |