Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q32TG3
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q32TG3-F1 | Predicted | AlphaFoldDB |
No variants for Q32TG3
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q32TG3 | |||||
No associated diseases with Q32TG3
No regional properties for Q32TG3
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q32TG3 | |||
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| axonemal microtubule | A microtubule in the axoneme of a eukaryotic cilium or flagellum; an axoneme contains nine modified doublet microtubules, which may or may not surround a pair of single microtubules. |
| axoneme | The bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements. |
| mitotic spindle | A spindle that forms as part of mitosis. Mitotic and meiotic spindles contain distinctive complements of proteins associated with microtubules. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| alpha-tubulin binding | Binding to the microtubule constituent protein alpha-tubulin. |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| cilium-dependent cell motility | Cell motility due to the motion of one or more eukaryotic cilia. A eukaryotic cilium is a specialized organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole. |
| mitotic cytokinesis | A cell cycle process that results in the division of the cytoplasm of a cell after mitosis, resulting in the separation of the original cell into two daughter cells. |
| mitotic spindle organization | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle. |
| regulation of neuron projection development | Any process that modulates the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites). |
3 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q5JST6 | EFHC2 | EF-hand domain-containing family member C2 | Homo sapiens (Human) | PR |
| Q9D485 | Efhc2 | EF-hand domain-containing family member C2 | Mus musculus (Mouse) | PR |
| Q32TF8 | efhc2 | EF-hand domain-containing family member C2 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MALPLLPGFS | LGRNVGKEKF | HKSQHWGYCN | NVAMLLAEDK | PGIGGEPLPG | QKLIPKSSVF |
| 70 | 80 | 90 | 100 | 110 | 120 |
| PAELGCGAPA | WLAFDKQVLS | FDAYFEEEVP | DKNQEPYRIR | HCKIYFYLED | DTIQVLEPQV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KNSGIIQGTI | VRRHRIPLPS | PNEDQFYTID | HFNINAEVIF | YARRYKIIDC | DQFTKHFLRK |
| 190 | 200 | 210 | 220 | 230 | 240 |
| MGFKLNPPGN | RPDDPYTKER | QKILDSMNPL | RPYERIDTLK | QFLEHDGHVL | RFYCVWDDPE |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SLFHDPRELV | LHYYLSDDTI | DIKEVIPVNS | GRDVVPLFLR | RDKLPKYAPT | GLYQPGTITS |
| 310 | 320 | 330 | 340 | 350 | 360 |
| RTVLNVFGNL | VGNRGRYILD | NRKTGAVHQE | FYRDSDLKIG | AVINVWGRQI | MLCDCDEFTK |
| 370 | 380 | 390 | 400 | 410 | 420 |
| DYYRTKYGIE | DFTPVPYKAP | PPPKAEKPIP | PYTGFGSEED | SLCSCMSLLP | KPPQKDFKKF |
| 430 | 440 | 450 | 460 | 470 | 480 |
| MEKDRCGLES | NTLRFLAKLV | TDSPIDKDRK | FIICYFLMMP | LYSVFEHSQR | NTGIIGGKFL |
| 490 | 500 | 510 | 520 | 530 | 540 |
| EKGRIKKPGQ | ELFKSEPSEY | FKAQDLFIGA | RVCFHGHNFL | LVDADEYTIN | YMEKHANEFA |
| 550 | 560 | 570 | 580 | 590 | 600 |
| VADTGFIFKK | LKDIAEPRSR | EIRQVFAAAD | PQHTKVIEYD | PFRNLIVSIT | DGAFSEHEIM |
| 610 | 620 | 630 | 640 | 650 | 660 |
| TLGRHYGEKE | EYEIDHHFLL | AKAQEQLKKN | SFENFEQLST | ILVYNDREKC | GALPYETCRT |
| 670 | 680 | 690 | 700 | 710 | 720 |
| ICKSFKLPLS | DDLLQTILTM | FEDDHKQVNY | KKFVDAVNWR | EHQIPSFHTI | KLPPKNEDDW |
| 730 | 740 | ||||
| NGQPPFLPVK | RIKYLPLLDD | LFGKEE |