Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q32TF8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q32TF8-F1 | Predicted | AlphaFoldDB |
No variants for Q32TF8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q32TF8 | |||||
No associated diseases with Q32TF8
3 regional properties for Q32TF8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | DM10 domain | 69 - 182 | IPR006602-1 |
| domain | DM10 domain | 219 - 366 | IPR006602-2 |
| domain | DM10 domain | 416 - 535 | IPR006602-3 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| axonemal microtubule | A microtubule in the axoneme of a eukaryotic cilium or flagellum; an axoneme contains nine modified doublet microtubules, which may or may not surround a pair of single microtubules. |
| axoneme | The bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements. |
| mitotic spindle | A spindle that forms as part of mitosis. Mitotic and meiotic spindles contain distinctive complements of proteins associated with microtubules. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| alpha-tubulin binding | Binding to the microtubule constituent protein alpha-tubulin. |
6 GO annotations of biological process
| Name | Definition |
|---|---|
| cilium-dependent cell motility | Cell motility due to the motion of one or more eukaryotic cilia. A eukaryotic cilium is a specialized organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole. |
| mitotic cytokinesis | A cell cycle process that results in the division of the cytoplasm of a cell after mitosis, resulting in the separation of the original cell into two daughter cells. |
| mitotic spindle organization | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle. |
| multi-ciliated epithelial cell differentiation | The process in which a relatively unspecialized cell acquires the specialized features of a multi-ciliated epithelial cell. |
| regulation of neuron projection development | Any process that modulates the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites). |
| specification of pronephric distal tubule identity | The process in which the distal tubule of the pronephric nephron acquires its identity. |
3 homologous proteins in AiPD
| 10 | 20 | 30 | 40 | 50 | 60 |
| MALPMLPGNS | VNRNLGKDKF | HKSQHFDYSN | GVAMMVGTEK | PGIGGDLLLG | QSARAKYSRF |
| 70 | 80 | 90 | 100 | 110 | 120 |
| PKGEGSGAPA | WLAFDKQVLC | FDAYFNEAVP | QRREEKYRVR | KCKIYFYLED | DTIQVVEPEF |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KNSGIPQGTL | IRRHRIPLPA | PKDDCFYNVH | HFNINQEVLF | YSRNFMITDC | DPFTRNFLVK |
| 190 | 200 | 210 | 220 | 230 | 240 |
| MGVRLNPPAS | TPADPYTTLR | QELEENMKPL | RPYERLDTLK | QFLEHDRQVL | RFYCYWDDSE |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SMFGDPRELI | LHYFLADDTM | EMYEVVPPNS | GRDTVPKFLH | RGKLPKHAPI | PKRQPGEITD |
| 310 | 320 | 330 | 340 | 350 | 360 |
| RTVLNVFGPV | GQGGPYILDS | LKTGALEEEF | YKDSDLTIGA | VINVWGRRVL | ICDCDYFTKE |
| 370 | 380 | 390 | 400 | 410 | 420 |
| YYRSKYGIED | FPSISYKASP | PPKPAKQVPP | YTGFGSEEDS | LCSCQGLLPK | PPQKDFKKLM |
| 430 | 440 | 450 | 460 | 470 | 480 |
| EKDRRGLVSN | VLRFVGKMLT | DSPVDKERVF | IICFYLTDDT | IAVFEPPQRN | SGVIGGKFLE |
| 490 | 500 | 510 | 520 | 530 | 540 |
| RGRVKKPGQE | LFKSEMSEYF | TAQDLYVGAH | LLLNSQPFQL | VDADDFTFSY | MEQHADEFPK |
| 550 | 560 | 570 | 580 | 590 | 600 |
| ANIGTIISKV | KSISEEQQKT | VKQFFTMSDP | SSTGSLPYES | FRTLLADLDV | ELSEHEIMTL |
| 610 | 620 | 630 | 640 | 650 | 660 |
| GRVYSVRQQP | EVNVGLMLAV | AQDHLKKKNF | EKFSEMIQAF | THEDRDRCGQ | LSSKEARIIC |
| 670 | 680 | 690 | 700 | 710 | 720 |
| KAFRLPLSDD | LLRALLEKFA | GESEKIDYHA | FLSGINWREN | PVPAVLPEDT | VKFDADWRGE |
| 730 | 740 | ||||
| APEPAVKTIN | YSLLLEDVFG | SATNINDS |