Q32PJ3

PR
Gene name
ORC3 (ORC3L)
Protein name
Origin recognition complex subunit 3
Names
Species
Bos taurus (Bovine)
KEGG Pathway
bta:523714
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

478-565 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q32PJ3

Entry ID Method Resolution Chain Position Source
AF-Q32PJ3-F1 Predicted AlphaFoldDB

No variants for Q32PJ3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q32PJ3

No associated diseases with Q32PJ3

3 regional properties for Q32PJ3

Type Name Position InterPro Accession
domain Origin recognition complex subunit 3, winged helix C-terminal 597 - 709 IPR040855
domain Origin recognition complex subunit 3, insertion domain 355 - 586 IPR045663
domain Origin recognition complex subunit 3, N-terminal 18 - 344 IPR045667

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
  • Chromosome
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
chromatin The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome.
nuclear origin of replication recognition complex A multisubunit complex that is located at the replication origins of a chromosome in the nucleus.

1 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).

2 GO annotations of biological process

Name Definition
DNA replication The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA.
regulation of DNA replication Any process that modulates the frequency, rate or extent of DNA replication.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9UBD5 ORC3 Origin recognition complex subunit 3 Homo sapiens (Human) PR
Q9JK30 Orc3 Origin recognition complex subunit 3 Mus musculus (Mouse) PR
10 20 30 40 50 60
MATSSVSKGC FVFKPNFKKR KISVPIEDYF NKGKNASEDS KLRFETYQLI WQQMKSETER
70 80 90 100 110 120
LQEELNKNLF DSLVEFLQTS HSGLWKNSKD WSCEIKLREI PTAALVLGVN VTDHDLTLRS
130 140 150 160 170 180
LTEVLQNNVT PYVVSLQAKD CPDMKHFLQK LVSQLMDCKV DVQSKEKESV QVIQKNVHYS
190 200 210 220 230 240
MDSLSAWYMS VTQKTDPKMP RKKRTSSSQW QSPPVVLILK DMESFTTKVL QDFIIISSQH
250 260 270 280 290 300
LHEFPLILIF GIATSPVVIH RLLPHAVSSL LCIELFQSLS CKEHLTTVLD KLLLTTQFPF
310 320 330 340 350 360
KLSEKVLQIL TNIFLYHDFS IQNFIKGLQL SLLEHFYSQP LSVLCCNLPE AKRRIRFLSA
370 380 390 400 410 420
NQCENIRRLP SFRRYVEKQS SEKQVALLTS DKFLKEETQS LLENLHVYHK NYFLVLRCLH
430 440 450 460 470 480
QFTSSLPKYP LGRQIRELYC MCLEKSIWDS EEYASVLQLL RLLAKDELMA MLQNCFKLFQ
490 500 510 520 530 540
SSSGKELGNT AKRIEEFLAQ FQSLDETKEE EDTSQSQSKG LQKTDLYHLQ KSLLEMKELR
550 560 570 580 590 600
STSKRQTKFE VLREQVVSFV DSLVREYLLP PDTQPLHETL YFSSAHTLRQ HLNAAPRIAL
610 620 630 640 650 660
HTALNNPYYY LKNEALRSEE GCIPNVAPDI CIAYKLHLEC SRLINLVDWS EAFATVVTAA
670 680 690 700 710
EKMDANSVTS GERNEIIHAR FIRAVSELEL LGFIKPTKQK TDHVARLTWG GC