Q2T9V2
Gene name |
IQCG (DRC9) |
Protein name |
Dynein regulatory complex protein 9 |
Names |
IQ domain-containing protein G |
Species |
Bos taurus (Bovine) |
KEGG Pathway |
bta:613455 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q2T9V2
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q2T9V2-F1 | Predicted | AlphaFoldDB |
No variants for Q2T9V2
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q2T9V2 | |||||
No associated diseases with Q2T9V2
1 regional properties for Q2T9V2
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| binding_site | IQ motif, EF-hand binding site | 388 - 417 | IPR000048 |
Functions
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| manchette | A tubular array of microtubules that extends from the perinuclear ring surrounding the spermatid nucleus to the flagellar axoneme. The manchette may also contain F-actin filaments. |
| motile cilium | A cilium which may have a variable arrangement of axonemal microtubules and also contains molecular motors. It may beat with a whip-like pattern that promotes cell motility or transport of fluids and other cells across a cell surface, such as on epithelial cells that line the lumenal ducts of various tissues; or they may display a distinct twirling motion that directs fluid flow asymmetrically across the cellular surface to affect asymmetric body plan organization. Motile cilia can be found in single as well as multiple copies per cell. |
| sperm flagellum | A microtubule-based flagellum (or cilium) that is part of a sperm, a mature male germ cell that develops from a spermatid. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| calmodulin binding | Binding to calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| sperm axoneme assembly | The assembly and organization of the sperm flagellar axoneme, the bundle of microtubules and associated proteins that forms the core of the eukaryotic sperm flagellum, and is responsible for movement. |
| spermatid development | The process whose specific outcome is the progression of a spermatid over time, from its formation to the mature structure. |
3 homologous proteins in AiPD
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEEGLEASNL | PPEAWPSEVT | VSVTGEPPNT | SVEEKEETAK | EAVIETSPEI | MKPLSILDVL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| RISAVLEDTT | DQLSILNYIM | PVQYEKRQSI | SMKDNKEMHL | EGRSSEKVPL | ASNPSKISSP |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LVHKEEPKLP | EIRQGGQFNK | VQDLIFKKPT | RQTIMNTETL | KKIQIDRQFL | SDVITETLEE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LQEEGTFTNL | LKALGKERES | KMHFYDTIAR | EENGRKKIKS | LQKQLLNVKK | ERQAEVQNRN |
| 250 | 260 | 270 | 280 | 290 | 300 |
| EYIAHLKDQL | QEMKAKTNME | NRYMKRNTEL | QISQTQKKCS | KTEELLLEEI | EKLRLKTEEE |
| 310 | 320 | 330 | 340 | 350 | 360 |
| NRIHAEIELF | LRKEQQKLEE | KLEFWMEKFD | KDTEMKQNEL | NALKSAKASD | LAHLQELAKT |
| 370 | 380 | 390 | 400 | 410 | 420 |
| IREYEQVIIE | DRIEKEKTRK | KREQDDLEMR | SIIKLQAWWR | GTVVRREIGG | FKMPKDKDDS |
| 430 | |||||
| KDVKGKGKEK | DKRRGKK |