Q28ET8
Gene name |
eif4e3 (TGas108j06.1) |
Protein name |
Eukaryotic translation initiation factor 4E type 3 |
Names |
eIF-4E type 3, eIF-4E3, eIF4E type 3, eIF4E-3 |
Species |
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) |
KEGG Pathway |
xtr:548803 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q28ET8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q28ET8-F1 | Predicted | AlphaFoldDB |
No variants for Q28ET8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q28ET8 | |||||
No associated diseases with Q28ET8
No regional properties for Q28ET8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q28ET8 | |||
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| eukaryotic translation initiation factor 4F complex | The eukaryotic translation initiation factor 4F complex is composed of eIF4E, eIF4A and eIF4G; it is involved in the recognition of the mRNA cap, ATP-dependent unwinding of the 5'-terminal secondary structure and recruitment of the mRNA to the ribosome. |
| mRNA cap binding complex | Any protein complex that binds to an mRNA cap at any time in the lifetime of the mRNA. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| RNA 7-methylguanosine cap binding | Binding to a 7-methylguanosine group added cotranscriptionally to the 5' end of RNA molecules transcribed by polymerase II. |
| translation initiation factor activity | Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
4 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| A3RCV9 | NCBP | Eukaryotic translation initiation factor NCBP | Triticum aestivum (Wheat) | PR |
| Q8N5X7 | EIF4E3 | Eukaryotic translation initiation factor 4E type 3 | Homo sapiens (Human) | PR |
| Q10NQ9 | NCBP | Eukaryotic translation initiation factor NCBP | Oryza sativa subsp japonica (Rice) | PR |
| Q66HY7 | eif4e3 | Eukaryotic translation initiation factor 4E type 3 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MALPAAPADR | RLQPEPDEQL | HLNHRELGEL | ALPQEPDTEG | IPLHSPWTFW | LDRSLPGTTA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| AECESNLKKI | YTVHTIQSFW | SVYNNIPQVT | NLPLRWSYHL | MRGERKPLWE | EESNAKGGVW |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KMKVPKEASS | LVWKELLLAT | IGEQFTDRCA | PEDEVIGVSV | SVRDREDVVQ | VWNGNASVVG |
| 190 | 200 | 210 | |||
| EATVLEKIYE | LLPNTSFKAV | FYKPHEEHHA | FEGGRSRH |