Q14BA6

PR
Gene name
Medag (Awms3, Meda4)
Protein name
Mesenteric estrogen-dependent adipogenesis protein
Names
Activated in W/Wv mouse stomach 3, mAWMS3, Mesenteric estrogen-dependent adipose 4, MEDA-4
Species
Mus musculus (Mouse)
KEGG Pathway
mmu:70717
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

232-303 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q14BA6

Entry ID Method Resolution Chain Position Source
AF-Q14BA6-F1 Predicted AlphaFoldDB

14 variants for Q14BA6

Variant ID(s) Position Change Description Diseaes Association Provenance
rs3388812883 10 A>T No EVA
rs3396368237 11 R>I No EVA
rs3396365857 12 P>L No EVA
rs3396346678 13 S>R No EVA
rs36515629 47 A>V No EVA
rs3388818988 62 E>K No EVA
rs29567946 66 A>E No EVA
rs33457502 81 E>D No EVA
rs3388807823 150 Q>H No EVA
rs3388796457 191 S>N No EVA
rs3388796467 242 M>K No EVA
rs3388813108 244 E>K No EVA
rs3388812905 245 P>H No EVA
rs3388801031 259 V>L No EVA

No associated diseases with Q14BA6

No regional properties for Q14BA6

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q14BA6

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
positive regulation of fat cell differentiation Any process that activates or increases the frequency, rate or extent of adipocyte differentiation.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
A4IFN2 MEDAG Mesenteric estrogen-dependent adipogenesis protein Bos taurus (Bovine) PR
Q5VYS4 MEDAG Mesenteric estrogen-dependent adipogenesis protein Homo sapiens (Human) PR
10 20 30 40 50 60
MATAACEPVA RPSLTSISSG ELRSLWTCDC ELALLPLSQL LRLQPGAFQL RGEQLLVPGP
70 80 90 100 110 120
GEPAAARGGF NVFGDGLVRL EGQLYRLSSY IKRYVELTNY CDYKDYRETI LSKPMVFFIN
130 140 150 160 170 180
VQTKKDISKE RTYAFLVNTR HPKIRRQIEQ GMDMVISSVI GESYRLQFDF QEVVKNFFPP
190 200 210 220 230 240
GTIVLNGENL SFTYEFKADA LFDFFYWFGL SNSTVKVHGK VLNLTSTNPE KKETIKLFLE
250 260 270 280 290 300
KMSEPLIRRS SFSDRKFSVT SRGSIDDVFN CNLSPRSSVT EPLLAEFSFP SLLECEETSS
QLI