A4IFN2

PR
Gene name
MEDAG
Protein name
Mesenteric estrogen-dependent adipogenesis protein
Names
Species
Bos taurus (Bovine)
KEGG Pathway
bta:510187
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

199-301 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A4IFN2

Entry ID Method Resolution Chain Position Source
AF-A4IFN2-F1 Predicted AlphaFoldDB

15 variants for A4IFN2

Variant ID(s) Position Change Description Diseaes Association Provenance
rs462702999 3 G>W No EVA
rs480488453 26 W>G No EVA
rs461799777 41 L>R No EVA
rs523419766 52 G>A No EVA
rs383646846 56 V>L No EVA
rs136609127 83 Q>R No EVA
rs137586654 128 L>S No EVA
rs451792097 155 V>I No EVA
rs469445625 156 I>S No EVA
rs433414525 156 I>V No EVA
rs478029592 185 V>G No EVA
rs462770018 195 E>V No EVA
rs447498633 234 T>S No EVA
rs135544431 247 I>V No EVA
rs381540982 259 V>I No EVA

No associated diseases with A4IFN2

No regional properties for A4IFN2

Type Name Position InterPro Accession
No domain, repeats, and functional sites for A4IFN2

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
positive regulation of fat cell differentiation Any process that activates or increases the frequency, rate or extent of adipocyte differentiation.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q5VYS4 MEDAG Mesenteric estrogen-dependent adipogenesis protein Homo sapiens (Human) PR
Q14BA6 Medag Mesenteric estrogen-dependent adipogenesis protein Mus musculus (Mouse) PR
10 20 30 40 50 60
MAGLESAPAA RPSLTSISSG ELRSLWTCDC ELALLPLGQL LRLQPGAFQL RGDQLVVPAP
70 80 90 100 110 120
AEPASARGGF NVFGDGFVRL DGQLYRLSSY MRRYVELTNY CDYKDYRETI LSKPMLFFVH
130 140 150 160 170 180
VQTKKDSLKE RTYAFLVNTR HPKIRRQIEQ GMDMVISSVI GESYRLQFDF QEVVKNFFPP
190 200 210 220 230 240
GNKVVNGEDL SFAYEFKADA LFDFFYWFGL SNSTVKVNGK VLNLSSTSPE KKETIKLFLE
250 260 270 280 290 300
KMSEPLIRRS SFSDRKFSVT SRGSIDEVFN CNLSPRSSLM EPLVAELPFP CVLESEETPN
PFI