Q12244
Gene name |
YLL054C (L0584) |
Protein name |
Uncharacterized transcriptional regulatory protein YLL054C |
Names |
|
Species |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
KEGG Pathway |
sce:YLL054C |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q12244
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q12244-F1 | Predicted | AlphaFoldDB |
26 variants for Q12244
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| s12-35033 | 57 | I>M | No | SGRP | |
| s12-35023 | 61 | P>S | No | SGRP | |
| s12-34857 | 116 | D>G | No | SGRP | |
| s12-34785 | 140 | E>G | No | SGRP | |
| s12-34089 | 372 | I>T | No | SGRP | |
| s12-34023 | 394 | Y>C | No | SGRP | |
| s12-33534 | 557 | I>T | No | SGRP | |
| s12-33490 | 572 | S>R | No | SGRP | |
| s12-33462 | 581 | C>S | No | SGRP | |
| s12-33424 | 594 | R>C | No | SGRP | |
| s12-33368 | 612 | E>D | No | SGRP | |
| s12-33352 | 618 | L>F | No | SGRP | |
| s12-33348 | 619 | L>R | No | SGRP | |
| s12-33300 | 635 | F>Y | No | SGRP | |
| s12-33277 | 643 | F>L | No | SGRP | |
| s12-33142 | 688 | Y>H | No | SGRP | |
| s12-33111 | 698 | I>T | No | SGRP | |
| s12-33094 | 704 | S>G | No | SGRP | |
| s12-32970 | 745 | Y>C | No | SGRP | |
| s12-32928 | 759 | G>A | No | SGRP | |
| s12-32919 | 762 | K>R | No | SGRP | |
| s12-32861 | 782 | E>K | No | SGRP | |
| s12-32843 | 788 | E>Q | No | SGRP | |
| s12-32827 | 793 | A>G | No | SGRP | |
| s12-32702 | 835 | G>R | No | SGRP | |
| s12-32690 | 839 | N>D | No | SGRP |
No associated diseases with Q12244
1 regional properties for Q12244
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Zn(2)Cys(6) fungal-type DNA-binding domain | 9 - 53 | IPR001138 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA-binding transcription factor activity, RNA polymerase II-specific | A DNA-binding transcription factor activity that modulates the transcription of specific gene sets transcribed by RNA polymerase II. |
| sequence-specific DNA binding | Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding. |
| zinc ion binding | Binding to a zinc ion (Zn). |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| positive regulation of transcription by RNA polymerase II | Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter. |
2 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P36023 | OAF3 | Oleate activated transcription factor 3 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| Q06639 | RSC3 | Chromatin structure-remodeling complex protein RSC3 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSIASQKKVK | PSFVCLRCKQ | RKIKCDKLWP | TCSKCKASSS | ICSYEVEPGR | INKSPTIENA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| PHRDIRNITP | ASMSASGSFT | SILNPSTKDW | EMKNFAMNLS | NAHDKLVVMN | NTTIVDSPFA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| FHSILQHDLY | AKALTTCIHE | RILIDVERHR | ENVSANNKKR | ELNLTIGDIG | PLFFIDKAAL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KFIENTSKTS | KLYPPIDFLY | NTYDYEQAHP | EENNDKISIN | ILLEELSKYF | LNKNEVDGLI |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VDFYKTIYPV | YPLLEISLFE | DNIRELLQLN | EFNGYNIVFA | GKDSRRKLET | ITLLTIILAF |
| 310 | 320 | 330 | 340 | 350 | 360 |
| SYRRLSLSTS | HSFKESFGVK | SNNLTLLAHK | LLALMNVFQY | VNEHTLCCLL | YFFILRYLNP |
| 370 | 380 | 390 | 400 | 410 | 420 |
| DQADMYPTHS | DILNLKFLEN | VAIKLGLNEE | PFQYTRYVSE | SDDYPRLFNL | RRKLWLGVQF |
| 430 | 440 | 450 | 460 | 470 | 480 |
| LKFGILIPEG | DSDILSLEYL | RSFMKTDESL | PELFERNYAS | TNNLDLSLMA | TAENIYHLHL |
| 490 | 500 | 510 | 520 | 530 | 540 |
| SLQVLLTSCF | PINGPSYLKE | VLDNIDKTKD | FLNQKFPLIL | SSLGEPRMKS | LHINVPSSLA |
| 550 | 560 | 570 | 580 | 590 | 600 |
| NEESFDFSTF | EENETFIANV | ISYTCTMNIY | DSLSLHFENQ | CFKNALEYKT | YYHRFTFTAI |
| 610 | 620 | 630 | 640 | 650 | 660 |
| QDYLTLLKLI | SEYFNGSLLH | LREPFGFATQ | KVVRFSIHRL | LIFQATLLVR | LFYKKDTCDR |
| 670 | 680 | 690 | 700 | 710 | 720 |
| SSAAMGMLND | RNGRLSRVIE | KMIKLMSYHM | KLLVEIVISK | LEKSYLGSFI | SVSIFRYIIY |
| 730 | 740 | 750 | 760 | 770 | 780 |
| LVDTDALSAF | ISDYWKSDAV | MDERYSRIHR | IVGLKWGMGR | DKSFSFTSKL | NNPQFLGSLD |
| 790 | 800 | 810 | 820 | 830 | 840 |
| LEILEELEKL | ISAQEFSRNF | TEDVDESLQS | EIDLMNYDNE | ALNQLMAIDL | DKLLGIFPNL |
| SNF |