P36023
Gene name |
OAF3 (YKR064W) |
Protein name |
Oleate activated transcription factor 3 |
Names |
|
Species |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
KEGG Pathway |
sce:YKR064W |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P36023
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P36023-F1 | Predicted | AlphaFoldDB |
21 variants for P36023
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| s11-562263 | 25 | R>S | No | SGRP | |
| s11-562354 | 56 | Q>K | No | SGRP | |
| s11-562381 | 65 | D>N | No | SGRP | |
| s11-562492 | 102 | V>I | No | SGRP | |
| s11-562501 | 105 | L>F | No | SGRP | |
| s11-562508 | 107 | N>S | No | SGRP | |
| s11-562574 | 129 | N>S | No | SGRP | |
| s11-562666 | 160 | A>T | No | SGRP | |
| s11-562823 | 212 | G>D | No | SGRP | |
| s11-562915 | 243 | S>G | No | SGRP | |
| s11-562981 | 265 | A>T | No | SGRP | |
| s11-563032 | 282 | V>I | No | SGRP | |
| s11-563089 | 301 | I>V | No | SGRP | |
| s11-563279 | 364 | N>I | No | SGRP | |
| s11-563283 | 365 | L>F | No | SGRP | |
| s11-563392 | 402 | S>A | No | SGRP | |
| s11-564244 | 686 | N>D | No | SGRP | |
| s11-564262 | 692 | D>N | No | SGRP | |
| s11-564357 | 723 | N>K | No | SGRP | |
| s11-564511 | 775 | E>K | No | SGRP | |
| s11-564656 | 823 | I>T | No | SGRP |
No associated diseases with P36023
1 regional properties for P36023
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Zn(2)Cys(6) fungal-type DNA-binding domain | 13 - 58 | IPR001138 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| mitochondrion | A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
| DNA-binding transcription factor activity, RNA polymerase II-specific | A DNA-binding transcription factor activity that modulates the transcription of specific gene sets transcribed by RNA polymerase II. |
| zinc ion binding | Binding to a zinc ion (Zn). |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| negative regulation of transcription by RNA polymerase II | Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II. |
| positive regulation of transcription by RNA polymerase II | Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter. |
2 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q12244 | YLL054C | Uncharacterized transcriptional regulatory protein YLL054C | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| Q06639 | RSC3 | Chromatin structure-remodeling complex protein RSC3 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGYDSQVRTK | KRHRITVVCT | NCKKRKSKCD | RTKPCGTCVR | LGDVDSCVYL | TDSSGQPESS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| PSLNDADPLR | KQSTPAERIS | PGFIKKRRSS | QTRQDEDHWQ | RVRELENQSS | LYYLPIHEET |
| 130 | 140 | 150 | 160 | 170 | 180 |
| PFFIDLIPNG | FYLETKRSAD | NLFGLFTDRA | IENRDPYLQA | MVTFRSIAIK | KMMDKLGSNG |
| 190 | 200 | 210 | 220 | 230 | 240 |
| NNVKNGSLPK | SFEALSTFDA | DDERHISDDV | VGKGNNFRMH | QTIHKSLFNK | FAQYRENNAK |
| 250 | 260 | 270 | 280 | 290 | 300 |
| KFSSETILAK | DYLPPLKILE | SEVLALFEEK | IYNMIPIFDM | KVLRHEITIF | YQNIVEKGNP |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ISIKHYDHMV | FCIILLIIKI | CRLSVQFSKL | TPYIYPVLQE | IDTSKFLALV | KHYLFETKVL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| RKCNLLQLQC | LILLRFLHWC | APEDGDGPET | QYCQILMGTI | ISSCKEMGIN | WYCFSHPEKY |
| 430 | 440 | 450 | 460 | 470 | 480 |
| SFKINRHTRP | SYDIMKPSDY | ISVFRKIWSY | VLFWDRKMCF | ISGEECQIGK | TLQCHFKEEA |
| 490 | 500 | 510 | 520 | 530 | 540 |
| DTPTWYIRML | TLDNLMKKIN | DTLNDDPGKV | DLNLLHRLIN | DLKRNFHILK | SLSKNEKETM |
| 550 | 560 | 570 | 580 | 590 | 600 |
| RHFDFEMEWI | IDLFSLSLLH | GEMIFYEYDC | NITKFYKSFQ | DLWDMVIHIS | EKCYNYFFNS |
| 610 | 620 | 630 | 640 | 650 | 660 |
| DALEVDSLTK | FYTNRIVEIV | ANKVLVIVPA | FILRGDRFKT | IQYADKKKMI | EFLYGVSSVY |
| 670 | 680 | 690 | 700 | 710 | 720 |
| FNEFGFEYYR | CFRKMFTAKI | AYKILNRSCE | KDAWRIILKF | LLNELKLEDN | GDSYIDYNDM |
| 730 | 740 | 750 | 760 | 770 | 780 |
| RLNDICPIIL | EFQETVQKYD | GYRPDILSIW | NNEFYPIGKY | NDDMTGFKFQ | MRIKEMQEFL |
| 790 | 800 | 810 | 820 | 830 | 840 |
| DMEKYSDRFN | IFSSFYDHAS | SQLAKHTEVD | TNISITNEQV | AEIPQKELLQ | QPLAPALPVN |
| 850 | 860 | ||||
| DLIVSEFDVI | EDIFDPVDFV | SFF |