Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q10T43

Entry ID Method Resolution Chain Position Source
AF-Q10T43-F1 Predicted AlphaFoldDB

No variants for Q10T43

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q10T43

No associated diseases with Q10T43

No regional properties for Q10T43

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q10T43

Functions

Description
EC Number 4.1.1.65 Carboxy-lyases
Subcellular Localization
  • [Phosphatidylserine decarboxylase 1 beta chain]: Mitochondrion inner membrane ; Single-pass membrane protein ; Intermembrane side
  • ;
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of mitochondrial inner membrane The component of the mitochondrial inner membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

1 GO annotations of molecular function

Name Definition
phosphatidylserine decarboxylase activity Catalysis of the reaction: H(+) + phosphatidyl-L-serine = CO(2) + phosphatidylethanolamine.

2 GO annotations of biological process

Name Definition
phosphatidylethanolamine biosynthetic process The chemical reactions and pathways resulting in the formation of phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine.
protein autoprocessing Processing which a protein carries out itself. This involves actions such as the autolytic removal of residues to generate the mature form of the protein.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P39006 PSD1 Phosphatidylserine decarboxylase proenzyme 1, mitochondrial Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PR
Q5JN42 PSD2 Phosphatidylserine decarboxylase proenzyme 2 Oryza sativa subsp japonica (Rice) PR
10 20 30 40 50 60
MRRFRVWPPS PSPWPLLASR PCPHSHHHRS PFHASANSGA RQGNFILPGA TAATLVMFGI
70 80 90 100 110 120
LHARRMYEDQ KVVERKEKGI EPEFSPDFKA SFLRLLPLRS MSRLWGSLME VELPVFMRPA
130 140 150 160 170 180
IYKAWARAFH SNLQEAAMPL EEYPSLQAFF IRSLKEGSRP IDADPNCLVS PVDGKVLRLG
190 200 210 220 230 240
ELRGPGTMIE QVKGFSYSAA SLLGASSSLH GAEEEDFSRE HTEQSNPADS NAKSWWRVSV
250 260 270 280 290 300
AKPKLWDQTL LSPKKGIFYC VIYLHPGDYH RVHSPVDWNI IKRRHFSGHL FPQNERAVRT
310 320 330 340 350 360
IRNLYVENER VVLEGQWKEG FVAIAAIGAT NVGSIKLYIE PELRTNRAGS KILNSQPEPP
370 380 390 400 410 420
DDRVYEPVGT GVMVKKGEEI AGFKMGSTVV MVFEAPVVSK ARWREDGSGT VTSDFDFCIK
430
AGDRIRVGEA IGRWTSRE