Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q0WQM8

Entry ID Method Resolution Chain Position Source
AF-Q0WQM8-F1 Predicted AlphaFoldDB

71 variants for Q0WQM8

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH13561197 2 V>M No 1000Genomes
ENSVATH04956202 4 D>N No 1000Genomes
ENSVATH04956201 6 V>A No 1000Genomes
ENSVATH01367460 15 I>L No 1000Genomes
ENSVATH01367460 15 I>V No 1000Genomes
ENSVATH04956192 30 I>T No 1000Genomes
ENSVATH01367454 30 I>V No 1000Genomes
ENSVATH04956191 42 E>G No 1000Genomes
ENSVATH01367453 46 D>N No 1000Genomes
ENSVATH13561193 52 E>K No 1000Genomes
ENSVATH04956185 54 D>N No 1000Genomes
ENSVATH01367447 54 D>V No 1000Genomes
ENSVATH01367446 56 G>C No 1000Genomes
ENSVATH13561192 59 P>H No 1000Genomes
ENSVATH04956184 83 P>L No 1000Genomes
ENSVATH01367445 89 D>Y No 1000Genomes
tmp_1_20080716_C_T 105 V>I No 1000Genomes
tmp_1_20080710_T_G 107 K>Q No 1000Genomes
tmp_1_20080703_C_A 109 W>L No 1000Genomes
ENSVATH04956182 120 E>V No 1000Genomes
tmp_1_20080665_A_C 122 F>V No 1000Genomes
ENSVATH00096653 125 M>I No 1000Genomes
ENSVATH14311041 142 G>S No 1000Genomes
ENSVATH04956181 145 F>L No 1000Genomes
tmp_1_20080583_G_A 149 S>L No 1000Genomes
ENSVATH01367444 151 H>Q No 1000Genomes
tmp_1_20080562_C_A 156 C>F No 1000Genomes
ENSVATH01367443 174 D>N No 1000Genomes
ENSVATH01367443 174 D>Y No 1000Genomes
ENSVATH04956179 178 E>K No 1000Genomes
ENSVATH01367441 195 L>P No 1000Genomes
ENSVATH04956178 199 V>I No 1000Genomes
ENSVATH13561187 200 I>N No 1000Genomes
ENSVATH13561188 200 I>V No 1000Genomes
ENSVATH04956177 205 T>M No 1000Genomes
tmp_1_20080335_C_T 232 V>I No 1000Genomes
ENSVATH13561186 235 Q>H No 1000Genomes
tmp_1_20080269_G_T 254 Q>K No 1000Genomes
ENSVATH01367438 263 H>N No 1000Genomes
ENSVATH04956174 284 G>D No 1000Genomes
ENSVATH01367436 290 A>T No 1000Genomes
tmp_1_20080157_C_T 291 G>E No 1000Genomes
tmp_1_20080158_C_T 291 G>R No 1000Genomes
ENSVATH04956172 300 M>I No 1000Genomes
tmp_1_20080130_A_G 300 M>T No 1000Genomes
ENSVATH13561185 303 C>S No 1000Genomes
ENSVATH14311040 303 C>Y No 1000Genomes
ENSVATH01367434 308 S>Y No 1000Genomes
tmp_1_20080103_T_A 309 E>V No 1000Genomes
ENSVATH14311039
tmp_1_20080096_A_C
311 F>L No 1000Genomes
tmp_1_20080079_T_A 317 H>L No 1000Genomes
ENSVATH01367432 318 V>E No 1000Genomes
ENSVATH01367433 318 V>I No 1000Genomes
tmp_1_20080063_C_T 322 M>I No 1000Genomes
tmp_1_20080061_T_A 323 N>I No 1000Genomes
ENSVATH13561164 351 W>* No 1000Genomes
ENSVATH01367430 364 C>Y No 1000Genomes
ENSVATH04956171 366 Y>N No 1000Genomes
tmp_1_20079929_G_A 367 A>V No 1000Genomes
ENSVATH13561163 372 W>R No 1000Genomes
tmp_1_20079903_C_A 376 V>F No 1000Genomes
tmp_1_20079897_G_A 378 H>Y No 1000Genomes
tmp_1_20079893_G_A 379 T>M No 1000Genomes
tmp_1_20079879_C_G 384 V>L No 1000Genomes
ENSVATH04956170 389 G>E No 1000Genomes
ENSVATH04956169 390 G>S No 1000Genomes
ENSVATH04956168 396 Q>H No 1000Genomes
ENSVATH04956167 404 Y>F No 1000Genomes
tmp_1_20079748_T_G 427 K>N No 1000Genomes
tmp_1_20079746_C_T 428 R>H No 1000Genomes
ENSVATH01367429 444 M>I No 1000Genomes

No associated diseases with Q0WQM8

3 regional properties for Q0WQM8

Type Name Position InterPro Accession
domain F-box domain 76 - 125 IPR001810
domain F-box associated domain, type 3 279 - 405 IPR013187
domain F-box associated interaction domain 181 - 412 IPR017451

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

16 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q5E9F9 PSMC2 26S proteasome regulatory subunit 7 Bos taurus (Bovine) PR
P35998 PSMC2 26S proteasome regulatory subunit 7 Homo sapiens (Human) PR
P46471 Psmc2 26S proteasome regulatory subunit 7 Mus musculus (Mouse) PR
Q63347 Psmc2 26S proteasome regulatory subunit 7 Rattus norvegicus (Rat) PR
Q9MAP1 At1g33020 Putative F-box protein At1g33020 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SY17 At1g30780 Probable F-box protein At1g30780 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LM89 At1g20657 Putative F-box protein At1g20657 Arabidopsis thaliana (Mouse-ear cress) PR
Q3ECH0 At1g67130 F-box protein At1g67130 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SA02 At1g31080 F-box protein At1g31080 Arabidopsis thaliana (Mouse-ear cress) PR
Q5BPS3 DOR F-box protein DOR Arabidopsis thaliana (Mouse-ear cress) PR
Q9FHP3 At5g65850 F-box protein At5g65850 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SZR7 At4g29970 Putative F-box protein At4g29970 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FT50 At3g52320 Putative F-box protein At3g52320 Arabidopsis thaliana (Mouse-ear cress) PR
Q3ECR3 At1g53360 Putative F-box protein At1g53360 Arabidopsis thaliana (Mouse-ear cress) PR
Q9T0J4 At4g38870 Putative F-box protein At4g38870 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SD70 At3g47030 F-box protein At3g47030 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MVRDIVDDPL DEDDIALVKT YGLVPYSAPI KKVEKEIKEL TEKINDLCGI KESDTGLAPL
70 80 90 100 110 120
SKQMMQEGQP LQVGYVSCFR YIPIDLLMDI FSRVPAKSIA RFRCVSKLWE SILCRPDFKE
130 140 150 160 170 180
LFMTMSSIRP PLLLFTFQDD DGNLFFFSSP HPQIPCNENT SLVPTRYHVQ HTTDSFSEIG
190 200 210 220 230 240
SPLCGFICRR GKRNLDTMVI CNPVTGESVS LPKVELKSIN TETRPYLGYD PVRKQLKVLC
250 260 270 280 290 300
IKSDDIPNTC DEHQVLTLEN GNHLWRTIQC KPHYPKSDGI CIDGILYYTA GFDMRARVSM
310 320 330 340 350 360
VVCFDVRSEK FSFINIHVFM LMNDSCTLIN YKGKLGALQF TCLSPKRLRF WVLVNAEKNI
370 380 390 400 410 420
WTKCIYALPP LWNNLVQHTE LAIVGMTDGG EVVLSQYCLI YAFYIYYFNL ESKSLTRVQI
430 440
QDVEMFKRTR VYTSLGYVEN FKLM