Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q0V9V7

Entry ID Method Resolution Chain Position Source
AF-Q0V9V7-F1 Predicted AlphaFoldDB

No variants for Q0V9V7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q0V9V7

No associated diseases with Q0V9V7

2 regional properties for Q0V9V7

Type Name Position InterPro Accession
domain RUN domain 52 - 184 IPR004012
domain RUN domain-containing protein 3A, RUN domain 30 - 180 IPR047338

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
positive regulation of cGMP-mediated signaling Any process that increases the rate, frequency or extent of cGMP-mediated signaling.

5 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q08E29 RUNDC3B RUN domain-containing protein 3B Bos taurus (Bovine) PR
Q17QK1 RUNDC3A RUN domain-containing protein 3A Bos taurus (Bovine) PR
Q59EK9 RUNDC3A RUN domain-containing protein 3A Homo sapiens (Human) PR
Q6PDC0 Rundc3b RUN domain-containing protein 3B Mus musculus (Mouse) PR
O08576 Rundc3a RUN domain-containing protein 3A Mus musculus (Mouse) PR
10 20 30 40 50 60
MEPSFIQSAM ALGLPSKKAS SRNIAVERKN LLTVCRFSVK TLLEKYTAEP IDDSSEEFVN
70 80 90 100 110 120
FAAILEHILS HRFKGHVSWF STDGQRGFWD YIRIACSKVT NNCISSIENM ENISSARAKG
130 140 150 160 170 180
RAWIRLALME KRLSEYIVTA LRDTRTTRRF YDDGAILLRE ESSVLTGMLI GLSAIDFSFC
190 200 210 220 230 240
LKGEGIDGKT PAVIDYTPYL KFTQSYDYLS EEDDRESVGG SSSEDSSPEH PYLPLLTDEE
250 260 270 280 290 300
SWYSKWRKME QKFRIVYAQK GYLEELVRLR ETQLKNLEAE NKRLTQRISE QAEQSLQEKH
310 320 330 340 350 360
QLEGVILELQ EQLTGLLPSE TAPIKQFTPS LGAPLVNQWP SLSTLNDNEA PVNPSLYRRH
370 380 390 400 410 420
SFLSTEHLSA ELSLSSESQR LDGKQDGEPW GPIGKDPTPS MLGLCGSLAS IPSCKSLPSL
430
KSNECLVSNS SETSPTGSPS