Q0P4Z1

PR
Gene name
retreg3 (fam134c, TNeu105l15.1)
Protein name
Reticulophagy regulator 3
Names
Species
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
KEGG Pathway
xtr:549426
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-58 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q0P4Z1

Entry ID Method Resolution Chain Position Source
AF-Q0P4Z1-F1 Predicted AlphaFoldDB

No variants for Q0P4Z1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q0P4Z1

No associated diseases with Q0P4Z1

No regional properties for Q0P4Z1

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q0P4Z1

Functions

Description
EC Number
Subcellular Localization
  • Endoplasmic reticulum membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

2 GO annotations of biological process

Name Definition
positive regulation of neuron projection development Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
reticulophagy The selective autohagy process in which parts of the endoplasmic reticulum are loaded into autophagosomes, delivered to the vacuole, and degraded in response to changing cellular conditions.

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q86VR2 RETREG3 Reticulophagy regulator 3 Homo sapiens (Human) PR
Q6NS82 Retreg2 Reticulophagy regulator 2 Mus musculus (Mouse) PR
Q9CQV4 Retreg3 Reticulophagy regulator 3 Mus musculus (Mouse) PR
10 20 30 40 50 60
MAQRVGEEEQ GASGLRRRRS GARCVEARER DEQVREVQEM LQRGLSSYEP VLSYVQAVLV
70 80 90 100 110 120
WERPRHSALL HLALNAAFWF FALTSLRIIF LVAFGLMIII CADQWKNKLW PELGAARASE
130 140 150 160 170 180
LENESWGYVH PRLLSVPELC YHAADTWVSV YNFLRNLLLF KTENPGKFCL LACSFLTFLA
190 200 210 220 230 240
VLGGYIPGVV LSYLLLLFLL LWPLAIYHQL GRRIYQKLEP ALQRLDFSVR GYMMSKYKER
250 260 270 280 290 300
QKHNRALPPT DASDSEEELA AFCPSLDDSA VAKELTISDS EHSDAEVSFT ENGTFNLSRG
310 320 330 340 350 360
QTPLTEGSED LDRHSDPEES FARDLPDFPS INPDATGIED DDETSIGIPS TALHPQFSSR
370 380 390 400 410 420
QLYEEQESLD AELSLGGFPS TQNITENIAG FVTRGMIQLA LAGASQQTHA YAESPRAKQY
430 440 450
QRNSSSELDT DAEADDFELL DQSELSQMDP SSSHSHQ