Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q0P4R6

Entry ID Method Resolution Chain Position Source
AF-Q0P4R6-F1 Predicted AlphaFoldDB

No variants for Q0P4R6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q0P4R6

No associated diseases with Q0P4R6

5 regional properties for Q0P4R6

Type Name Position InterPro Accession
domain RNA recognition motif domain 61 - 139 IPR000504-1
domain RNA recognition motif domain 141 - 223 IPR000504-2
domain RNA recognition motif domain 236 - 308 IPR000504-3
domain Probable RNA-binding protein 46, RNA recognition motif 2 139 - 223 IPR034435
domain RBM46, double-stranded RNA binding domain 392 - 469 IPR044462

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

2 GO annotations of molecular function

Name Definition
mRNA binding Binding to messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
RNA binding Binding to an RNA molecule or a portion thereof.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

4 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
A0AV96 RBM47 RNA-binding protein 47 Homo sapiens (Human) PR
Q8TBY0 RBM46 Probable RNA-binding protein 46 Homo sapiens (Human) PR
P86049 Rbm46 Probable RNA-binding protein 46 Mus musculus (Mouse) PR
Q0P4R6 rbm46 Probable RNA-binding protein 46 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) PR
10 20 30 40 50 60
MEDNCTDMFN GCSKFDISIQ TQVALLALID NTGYTMVQVN GQRKFGGPPP GWEGPPPPRG
70 80 90 100 110 120
CEVFVGKIPR DMYEDKLVPL FARAGKIYEF RLMMEFSGEN RGYAFVMYTN KEEALLAIRM
130 140 150 160 170 180
LNNYEICQGK FIGVCVSLDN CRLFIGSIPQ EKRKEEILEE MKKVTEGVMD VIVYPSATDK
190 200 210 220 230 240
TKNRGFAFVM YESHRAAAMA RRKLIPGPFQ LWGHTIKVAW ASPEKEVDEE TMQKVKVLYV
250 260 270 280 290 300
RNLMMSTTEE TIKAEFNRYK PGVVERVKKI RDYAFVHFFR RDYAIAAMSV MNGRLIDGAR
310 320 330 340 350 360
IEVTLAKPVN KEAAWRQNGN GHMNANSECL LNFANKEGSQ KALDMCSNVP AYLNNPNSPT
370 380 390 400 410 420
FLEPETCTYP CIPGTKLTPI NLYSLKIHHF HSAVMHLEYF CYKNNWSFPE YYLYSTTGQD
430 440 450 460 470 480
GKMLLAYKVI LPAITGNTNS YFMPDKLCSF VEDAKELAAQ FTLMHLDYSY HPTSGKNISL
490 500 510 520 530
PSTAATSGTS GVLPYTPKPY SYSSYPSSPN VSLTNGGSVG KQLYVSNQAS YFSG