Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q0DKM0

Entry ID Method Resolution Chain Position Source
AF-Q0DKM0-F1 Predicted AlphaFoldDB

No variants for Q0DKM0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q0DKM0

No associated diseases with Q0DKM0

No regional properties for Q0DKM0

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q0DKM0

Functions

Description
EC Number 2.7.13.3 Protein-histidine kinases
Subcellular Localization
  • Endoplasmic reticulum membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
endoplasmic reticulum The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
endoplasmic reticulum membrane The lipid bilayer surrounding the endoplasmic reticulum.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

5 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ethylene binding Binding to ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator.
ethylene receptor activity Combining with ethylene and transmitting the signal in the cell to initiate a change in cell activity.
metal ion binding Binding to a metal ion.
phosphorelay sensor kinase activity Catalysis of the phosphorylation of a histidine residue in response to detection of an extracellular signal such as a chemical ligand or change in environment, to initiate a change in cell state or activity. The two-component sensor is a histidine kinase that autophosphorylates a histidine residue in its active site. The phosphate is then transferred to an aspartate residue in a downstream response regulator, to trigger a response.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

5 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
A1A696 HK3 Probable histidine kinase 3 Oryza sativa subsp japonica (Rice) PR
Q0DWC7 ETR3 Ethylene receptor 3 Oryza sativa subsp japonica (Rice) PR
Q53RH0 ERS1 Probable ethylene response sensor 1 Oryza sativa subsp japonica (Rice) PR
Q38846 ERS1 Ethylene response sensor 1 Arabidopsis thaliana (Mouse-ear cress) PR
O49187 ETR2 Ethylene receptor 2 Solanum lycopersicum (Tomato) (Lycopersicon esculentum) PR
10 20 30 40 50 60
MDGSCDCIEP LWQADDLLVK YQYISDFFIA LAYFSIPLEL IYFVKKSAFF PYRWVLIQFG
70 80 90 100 110 120
AFIVLCGATH LINLWTFAIY TKTIAVVLTV AKAATAVVSC ITALMLVHII PDLLNVKLRE
130 140 150 160 170 180
RFLKDKADEL DREMGIIRTQ EETGRHVHML THEIRSTLDR HTILRTTLVE LGRTLVLAEC
190 200 210 220 230 240
ALWMPTRSGS ALQLSHTIYN SAAIGSVVPI NLPIVSKVFN SNRVVKIPHT SPLASITADK
250 260 270 280 290 300
SRYVPPEVVA IRVPLLHLTN FQINDWPELS AKSFAVMVLM LPPDSAREWR PHERELVEVV
310 320 330 340 350 360
ADQVAVALSH AAILEESMRA RDLLMEQNIA LDAARREAEM AICARNDFLA VMNHEMRTPM
370 380 390 400 410 420
RAIVSLSSLL LETNLSAEQR LMVETILKSS DLLATLTNDV LDVSKLENGS LELEIAPFNL
430 440 450 460 470 480
HSTFTDVVNL IKPVAACKRL SVMVTLAPEL PLHAIGDQKR LMQIILNVAG NSIKFTKEGH
490 500 510 520 530 540
VSITASMARP DALRGPHEPD YHPVVSDGFF YLAVQVKDTG CGISPQDMPH TFRKFAHPEN
550 560 570 580 590 600
AGKWNSGSGL GLALSRRFVS LMEGNIWLES EGVGKGCTAM FFVKLGMPEK PNANLRRMAP
610 620 630
HPLQPNQGAG GPDALSISIM DSNPRVPRVR YQSSV