O49187
Gene name |
ETR2 |
Protein name |
Ethylene receptor 2 |
Names |
LeETR2 |
Species |
Solanum lycopersicum (Tomato) (Lycopersicon esculentum) |
KEGG Pathway |
sly:606299 |
EC number |
2.7.13.3: Protein-histidine kinases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O49187
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O49187-F1 | Predicted | AlphaFoldDB |
No variants for O49187
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O49187 | |||||
No associated diseases with O49187
Functions
| Description | ||
|---|---|---|
| EC Number | 2.7.13.3 | Protein-histidine kinases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| endoplasmic reticulum | The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached). |
| endoplasmic reticulum membrane | The lipid bilayer surrounding the endoplasmic reticulum. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
5 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ethylene binding | Binding to ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator. |
| ethylene receptor activity | Combining with ethylene and transmitting the signal in the cell to initiate a change in cell activity. |
| metal ion binding | Binding to a metal ion. |
| phosphorelay sensor kinase activity | Catalysis of the phosphorylation of a histidine residue in response to detection of an extracellular signal such as a chemical ligand or change in environment, to initiate a change in cell state or activity. The two-component sensor is a histidine kinase that autophosphorylates a histidine residue in its active site. The phosphate is then transferred to an aspartate residue in a downstream response regulator, to trigger a response. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| anatomical structure development | The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. |
| negative regulation of ethylene-activated signaling pathway | Any process that stops or prevents ethylene (ethene) signal transduction. |
5 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| A1A696 | HK3 | Probable histidine kinase 3 | Oryza sativa subsp japonica (Rice) | PR |
| Q0DWC7 | ETR3 | Ethylene receptor 3 | Oryza sativa subsp japonica (Rice) | PR |
| Q53RH0 | ERS1 | Probable ethylene response sensor 1 | Oryza sativa subsp japonica (Rice) | PR |
| Q0DKM0 | ERS2 | Probable ethylene response sensor 2 | Oryza sativa subsp japonica (Rice) | PR |
| Q38846 | ERS1 | Ethylene response sensor 1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MDCNCFDPLL | PADELLMKYQ | YISDFFIAVA | YFSIPIELVY | FVQKSAVFPY | RWVLVQFGAF |
| 70 | 80 | 90 | 100 | 110 | 120 |
| IVLCGATHLI | NLWTSTPHTR | TVAMVMTTAK | FSTAAVSCAT | AVMLVHIIPD | LLSVKTRELF |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LKNKAAELDR | EMGLIRTQEE | TGRYVRMLTH | EIRSTLDRHT | ILKTTLVELG | RALQLEECAL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| WMPTRTGVEL | QLSYTLHHQN | PVGFTVPIQL | PVINQVFSAN | CAVKISPNSA | VARLRPTRKY |
| 250 | 260 | 270 | 280 | 290 | 300 |
| IPGEVVAVRV | PLLHLSNFQT | NDWPELSPKS | YALMVLMLPS | NSARQWHVHE | LELVDVVADQ |
| 310 | 320 | 330 | 340 | 350 | 360 |
| VAVALSHAAI | LEESMRARDL | LIEQNVALDL | ARREAETAVR | ARNDFLGVMN | HEMRTPMHAV |
| 370 | 380 | 390 | 400 | 410 | 420 |
| VALSSLLQES | ELIPEQRLMV | ETILKSSNLL | ATLINDVLDL | SRLEDGSLQL | DVGTFNLHAL |
| 430 | 440 | 450 | 460 | 470 | 480 |
| FREVLNLIKP | VAAVKKLFVT | LSLSSDFPEV | AIGDEKRLMQ | ILLNVVGNAV | KFSKEGSVSV |
| 490 | 500 | 510 | 520 | 530 | 540 |
| SAVNAKSESL | IDPRAPEFFP | VQSENHFYLR | VQVKDTGSGI | NPQDFPKLFC | KFAQNQEPAT |
| 550 | 560 | 570 | 580 | 590 | 600 |
| KNSAGTGLGL | AICKRFVNLM | EGHIWIESEG | VGKGSTAIFI | VKLGIPGRLN | ESKLPFTAGL |
| 610 | 620 | 630 | 640 | 650 | 660 |
| PANHMQMTFQ | GLKVLVMDDN | GFSRMVTKSL | LVHLGCDVTT | IGSGDECLRI | LTREHKVLIM |
| 670 | 680 | 690 | 700 | 710 | 720 |
| DASITGMNCY | DVAVSVHEKF | GKRLERPLIV | ALTGNTDQVT | KENCLRVGMD | GVILKPVSID |
| 730 | |||||
| KMRSVLSGLL | EHGTVL |