Q01163

PR
Gene name
RSM23 (YGL129C, G2856)
Protein name
37S ribosomal protein S23, mitochondrial
Names
DAP-3, Mitochondrial small ribosomal subunit protein mS29
Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
KEGG Pathway
sce:YGL129C
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-84 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

9 structures for Q01163

Entry ID Method Resolution Chain Position Source
5MRC EM 325 A WW 50-450 PDB
5MRE EM 375 A WW 50-450 PDB
5MRF EM 497 A WW 50-450 PDB
8D8K EM 313 A W 1-450 PDB
8D8L EM 260 A W 1-450 PDB
8OM2 EM 257 A W 1-450 PDB
8OM3 EM 287 A W 1-450 PDB
8OM4 EM 232 A W 1-450 PDB
AF-Q01163-F1 Predicted AlphaFoldDB

3 variants for Q01163

Variant ID(s) Position Change Description Diseaes Association Provenance
s07-268621 154 V>L No SGRP
s07-268284 266 H>R No SGRP
s07-267925 386 V>I No SGRP

No associated diseases with Q01163

No regional properties for Q01163

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q01163

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion
  • Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner membrane protein MBA1
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
mitochondrial inner membrane The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
mitochondrial small ribosomal subunit The smaller of the two subunits of a mitochondrial ribosome.
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

2 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
structural constituent of ribosome The action of a molecule that contributes to the structural integrity of the ribosome.

1 GO annotations of biological process

Name Definition
mitochondrial translation The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P82922 DAP3 28S ribosomal protein S29, mitochondrial Bos taurus (Bovine) PR
P51398 DAP3 28S ribosomal protein S29, mitochondrial Homo sapiens (Human) PR
10 20 30 40 50 60
MLRMSTSRFI GQRLFTTARS LQAAKPAPKG KTQGFSKKSS SVSSYSSAKR VTPGSLYKNW
70 80 90 100 110 120
TNTTHTAQLQ QTAVPLALPI FNFDDISKTL NKVVSYSNKQ YKSLHHLGSF KKSQFNELFQ
130 140 150 160 170 180
KPVCLVREDA TNSFLKKLVS HPVKKFIITG EPGVGKTVLL SQAHAYAVDS KQIIINISYP
190 200 210 220 230 240
ELFLNGRNDF SYDDDLKLFI QPMYLKKLIR KILKANDPAL LKSIELSKDY KFSNANPKNA
250 260 270 280 290 300
SVKPFVTLNK TKNTVLDLLS VMTHPHNRGK LMKAIIDELS VQSKVPIMFT VDNFSKVLTT
310 320 330 340 350 360
AYSAYRNTEN KQIYSLDLQM GKLMMDIISG ETKFANGESS TILAISGVDR TNKTLPVALG
370 380 390 400 410 420
KIPVDPYVTR YHYEPKFVEL LQKGNVTEFE VPKLNKQEVN ELIDYYKQSN VLLDKDITGK
430 440
KWENLIDEKY FLSGNGNPRE LLKSLVLSHR