Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for P52108

Entry ID Method Resolution Chain Position Source
AF-P52108-F1 Predicted AlphaFoldDB

No variants for P52108

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P52108

No associated diseases with P52108

2 regional properties for P52108

Type Name Position InterPro Accession
domain Signal transduction response regulator, receiver domain 2 - 116 IPR001789
domain OmpR/PhoB-type DNA-binding domain 136 - 235 IPR001867

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
protein-DNA complex A macromolecular complex containing both protein and DNA molecules.

3 GO annotations of molecular function

Name Definition
DNA-binding transcription activator activity A DNA-binding transcription factor activity that activates or increases transcription of specific gene sets.
phosphorelay response regulator activity Responds to a phosphorelay sensor to initiate a change in cell state or activity. The activity of the response regulator is regulated by transfer of a phosphate from a histidine residue in the sensor, to an aspartate residue in the response regulator. Many but not all response regulators act as transcriptional regulators to elicit a response.
transcription cis-regulatory region binding Binding to a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P0A9Q1 arcA Aerobic respiration control protein ArcA Escherichia coli (strain K12) PR
P0AE88 cpxR Transcriptional regulatory protein CpxR Escherichia coli (strain K12) PR
10 20 30 40 50 60
MNTIVFVEDD AEVGSLIAAY LAKHDMQVTV EPRGDQAEET ILRENPDLVL LDIMLPGKDG
70 80 90 100 110 120
MTICRDLRAK WSGPIVLLTS LDSDMNHILA LEMGACDYIL KTTPPAVLLA RLRLHLRQNE
130 140 150 160 170 180
QATLTKGLQE TSLTPYKALH FGTLTIDPIN RVVTLANTEI SLSTADFELL WELATHAGQI
190 200 210 220 230
MDRDALLKNL RGVSYDGLDR SVDVAISRLR KKLLDNAAEP YRIKTVRNKG YLFAPHAWE