P48984
Gene name |
TEAD4 (TEF-1, TEF3) |
Protein name |
Transcriptional enhancer factor TEF-3 |
Names |
M-CAT-binding factor, RTEF-1, TEA domain family member 4, TEAD-4, TEF-1 |
Species |
Gallus gallus (Chicken) |
KEGG Pathway |
gga:395542 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P48984
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P48984-F1 | Predicted | AlphaFoldDB |
No variants for P48984
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P48984 | |||||
No associated diseases with P48984
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
| transcription regulator complex | A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA-binding transcription factor activity, RNA polymerase II-specific | A DNA-binding transcription factor activity that modulates the transcription of specific gene sets transcribed by RNA polymerase II. |
| RNA polymerase II cis-regulatory region sequence-specific DNA binding | Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase II. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| embryonic organ development | Development, taking place during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. |
| hippo signaling | The series of molecular signals mediated by the serine/threonine kinase Hippo or one of its orthologs. In Drosophila, Hippo in complex with the scaffold protein Salvador (Sav), phosphorylates and activates Warts (Wts), which in turn phosphorylates and inactivates the Yorkie (Yki) transcriptional activator. The core fly components hippo, sav, wts and mats are conserved in mammals as STK4/3 (MST1/2), SAV1/WW45, LATS1/2 and MOB1. |
| regulation of transcription by RNA polymerase II | Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II. |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTSEWSSPAS | PEGSNDSGGS | EALDKPIDND | AEGVWSPDIE | QSFQEALAIY | PPCGRRKIIL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SDEGKMYGRN | ELIARYIKLR | TGKTRTRKQV | SSHIQVLARR | KAREIQAKLK | KTQVDKYDFS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SEKDQTAKDK | AMQSIATMSS | AQIISATAFH | SKMALPGLPR | SAYPAVSGFW | QGALPGQAGS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SQDVKPFTQQ | PYALQPSLPL | PGFDSPTGLP | PSSSTPAWQG | RRVASSKLWM | LEFSAFLEQQ |
| 250 | 260 | 270 | 280 | 290 | 300 |
| QDQDTYNKHL | FVHIGQSNPS | YSDPYLEAVD | IRQIYDKFPE | KKGGLKELFE | RGPANAFFLV |
| 310 | 320 | 330 | 340 | 350 | 360 |
| KFWADLNTNI | EDESRSFYGV | SSQYESPENM | VITCSTKVCS | FGKQVVEKVE | TEYAHYENGH |
| 370 | 380 | 390 | 400 | 410 | 420 |
| YAYRIHRSPL | CEYMINFIHK | LKHLPEKYMM | NSVLENFTIL | QVVTNRDTQE | TLLCIAYVFE |
| 430 | |||||
| VSASDHGAQH | HIYRLVKD |