P46654
Gene name |
RPS0B |
Protein name |
40S ribosomal protein S0-B |
Names |
Nucleic acid-binding protein NAB1B, Small ribosomal subunit protein uS2-B |
Species |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
KEGG Pathway |
sce:YLR048W |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
2 structures for P46654
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 6WOO | EM | 290 A | AA | 2-207 | PDB |
| AF-P46654-F1 | Predicted | AlphaFoldDB |
1 variants for P46654
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| s12-242788 | 66 | A>G | No | SGRP |
No associated diseases with P46654
2 regional properties for P46654
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Ribosomal protein S2, conserved site | 14 - 25 | IPR018130-1 |
| conserved_site | Ribosomal protein S2, conserved site | 118 - 142 | IPR018130-2 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| cytosolic small ribosomal subunit | The small subunit of a ribosome located in the cytosol. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| structural constituent of ribosome | The action of a molecule that contributes to the structural integrity of the ribosome. |
6 GO annotations of biological process
| Name | Definition |
|---|---|
| cytoplasmic translation | The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein. |
| endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | Endonucleolytic cleavage between the SSU-rRNA and the 5.8S rRNA of an rRNA molecule originally produced as a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript. |
| endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | Endonucleolytic cleavage at the 3'-end of the SSU-rRNA from an originally tricistronic rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript, to produce the mature end of the SSU-rRNA. |
| ribosomal small subunit assembly | The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the small ribosomal subunit. |
| rRNA export from nucleus | The directed movement of rRNA from the nucleus to the cytoplasm; the rRNA is usually in the form of ribonucleoproteins. |
| translation | The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome. |
3 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P32905 | RPS0A | 40S ribosomal protein S0-A | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| P38979 | sta | 40S ribosomal protein SA | Drosophila melanogaster (Fruit fly) | PR |
| P46769 | rps-0 | 40S ribosomal protein SA | Caenorhabditis elegans | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSLPATFDLT | PEDAQLLLAA | NTHLGARNVQ | VHQEPYVFNA | RPDGVHVINV | GKTWEKLVLA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ARIIAAIPNP | EDVVAISSRT | YGQRAVLKFA | AHTGATPIAG | RFTPGSFTNY | ITRSFKEPRL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VIVTDPRLDA | QAIKEASYVN | IPVIALTDLD | SPSEFVDVAI | PCNNRGKHSI | GLIWYLLARE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VLRLRGALVD | RTQPWSIMPD | LYFYRNPEEV | EQVAEEAAAA | EEGEEEEVKE | EVTEGQAEAT |
| 250 | |||||
| EWAEENADNV | EW |